1. [Rare occurrence of fulminant acid burn of the esophagus].
- Author
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Knebel C, Bumm R, Becker K, Burian M, and Siewert JR
- Subjects
- Anti-Ulcer Agents administration & dosage, Disease Progression, Duodenal Neoplasms diagnosis, Duodenal Neoplasms pathology, Duodenum pathology, Duodenum surgery, Endoscopy, Digestive System, Esophageal Perforation diagnosis, Esophageal Perforation pathology, Esophagectomy, Esophagitis, Peptic diagnosis, Esophagitis, Peptic pathology, Esophagus pathology, Follow-Up Studies, Gastrectomy, Gastric Mucosa pathology, Gastrinoma diagnosis, Gastrinoma pathology, Gastroesophageal Reflux diagnosis, Gastroesophageal Reflux pathology, Gastroesophageal Reflux surgery, Humans, Lymph Node Excision, Lymphatic Metastasis pathology, Male, Middle Aged, Necrosis, Proton Pump Inhibitors, Reoperation, Treatment Refusal, Zollinger-Ellison Syndrome diagnosis, Zollinger-Ellison Syndrome pathology, Zollinger-Ellison Syndrome surgery, Duodenal Neoplasms complications, Duodenal Neoplasms surgery, Esophageal Perforation surgery, Esophagitis, Peptic surgery, Gastrinoma complications, Gastrinoma surgery
- Abstract
Peptic ulcer due to Zollinger-Ellison syndrome is a rare entity. In this case report a 55-year-old man had a medical history of esophageal reflux, vomiting, and diarrhea for 10 years. Despite continuous medication with a proton pump inhibitor, no complete recovery from symptoms was achieved. A diagnosis of gastrinoma was at first not considered. After discontinuation of the proton pump inhibitor for only a few days, the strong stimulation of the gastrinoma led to fulminant hydrochloric acid burn of the distal esophagus with iatrogenic or spontaneous perforation at the esophagogastral junction. We describe the operative treatment as a two-stage reconstruction with colon interposition and resection of the primary tumor in the duodenum.
- Published
- 2008
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