1. Comparison of the axial growth with multifocal and monofocal intraocular lenses in unilateral pediatric cataract surgery.
- Author
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Du Q, Ding Y, Liu X, and Huang Y
- Subjects
- Humans, Female, Male, Child, Child, Preschool, Prospective Studies, Follow-Up Studies, Multifocal Intraocular Lenses, Lens Implantation, Intraocular, Vitrectomy methods, Pseudophakia physiopathology, Lenses, Intraocular, Refraction, Ocular physiology, Prosthesis Design, Retrospective Studies, Axial Length, Eye, Visual Acuity physiology, Cataract Extraction, Cataract congenital, Cataract physiopathology
- Abstract
Purpose: To compare axial growth in pediatric cataract patients who underwent multifocal intraocular lens (IOL) implantation without anterior vitrectomy (AV) with that in pediatric patients who underwent monofocal IOL implantation with or without AV., Methods: Patients who had unilateral pediatric cataracts and underwent surgery at 3-6 years of age from June 6, 2019, to June 30, 2020, at our institution were prospectively analyzed. The patients were categorized into Group A: multifocal IOL implantation with optic capture in Berger's space without AV; Group B: monofocal IOL implantation with optic capture in Berger's space without AV; and Group C: bag-in-the-lens monofocal IOL implantation with AV. Groups A', B' and C' consisted of the fellow eyes from the respective groups. Axial growth and monthly growth rates were compared among the 3 treatment groups, as well as between the treated eyes and the fellow eyes., Results: Thirty-one, 23, and 14 children fulfilling the inclusion criteria, respectively, were included in the final analysis. There were no significant differences in patient age at the time of surgery or preoperative axial length (P > 0.05). After a mean follow-up of 35.57 ± 3.78 months, significant differences in the axial growth and the monthly growth rate were observed (P < 0.05), and Group A had the least axial elongation. Comparing treated eyes with fellow eyes, the amount and rate of axial growth were lower in Group A than in Group A' (P < 0.05), no significant differences were found in Group B (P > 0.05), and Group C had greater growth than did Group C' (P < 0.05)., Conclusions: The implanting multifocal intraocular lenses and maintenance of vitreous body integrity may be protective factors against excessive axial growth in pediatric cataract patients. Clinical trial registration (prospective study): chiCRT1900023155; 2019-05-14., Competing Interests: Declarations. Ethics approval: The study was performed with approval from the Medical Ethics Committee of Qingdao Eye Hospital of Shandong First Medical University, and informed consent was provided by the parents of all the included pediatric patients. Conflict of interest: There are no conflicts of interest. All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2024
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