1. The neural basis of egocentric and allocentric coding of space in humans: a functional magnetic resonance study
- Author
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E. Lobel, Gaspare Galati, Alain Berthoz, Giuseppe Vallar, Luigi Pizzamiglio, Denis Le Bihan, Galati, G, Lobel, E, Vallar, G, Berthoz, A, Pizzamiglio, L, Le Bihan, D, Geometry and Probability for Motion and Action (E-MOTION), Laboratoire d'informatique GRAphique, VIsion et Robotique de Grenoble (GRAVIR - IMAG), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National Polytechnique de Grenoble (INPG)-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National Polytechnique de Grenoble (INPG)-Centre National de la Recherche Scientifique (CNRS)-Inria Grenoble - Rhône-Alpes, Institut National de Recherche en Informatique et en Automatique (Inria), Laboratoire de Physiologie de la Perception et de l'Action (LPPA), Collège de France (CdF (institution))-Centre National de la Recherche Scientifique (CNRS), Service NEUROSPIN (NEUROSPIN), Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), IFR de Neuroimagerie Fonctionnelle (IFR 49), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Service Hospitalier Frédéric Joliot (SHFJ), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique de Grenoble (INPG)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique de Grenoble (INPG)-Inria Grenoble - Rhône-Alpes, Direction de Recherche Fondamentale (CEA) (DRF (CEA)), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay
- Subjects
Male ,genetic structures ,[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging ,MESH: Frontal Lobe ,spatial reference frame ,Functional Laterality ,MESH: Magnetic Resonance Imaging ,0302 clinical medicine ,Oculomotor Nerve ,Parietal Lobe ,MESH: Parietal Lobe ,right hemisphere ,medicine.diagnostic_test ,General Neuroscience ,05 social sciences ,Neuropsychology ,Human brain ,Magnetic Resonance Imaging ,Frontal Lobe ,MESH: Photic Stimulation ,medicine.anatomical_structure ,Female ,Psychology ,object-based ,hemineglect ,mid-sagittal plane ,object based ,spatial ,spatial reference frames ,Reference frame ,Adult ,MESH: Space Perception ,MESH: Psychomotor Performance ,Stimulus (physiology) ,M-PSI/02 - PSICOBIOLOGIA E PSICOLOGIA FISIOLOGICA ,050105 experimental psychology ,Lateralization of brain function ,Perceptual Disorders ,03 medical and health sciences ,medicine ,Humans ,0501 psychology and cognitive sciences ,MESH: Functional Laterality ,MESH: Perceptual Disorders ,MESH: Oculomotor Nerve ,MESH: Humans ,MESH: Adult ,Magnetic resonance imaging ,Neurophysiology ,MESH: Male ,Space Perception ,Functional magnetic resonance imaging ,MESH: Female ,Neuroscience ,Photic Stimulation ,Psychomotor Performance ,030217 neurology & neurosurgery - Abstract
International audience; The spatial location of an object can be represented in the brain with respect to different classes of reference frames, either relative to or independent of the subject's position. We used functional magnetic resonance imaging to identify regions of the healthy human brain subserving mainly egocentric or allocentric (object-based) coordinates by asking subjects to judge the location of a visual stimulus with respect to either their body or an object. A color-judgement task, matched for stimuli, difficulty, motor and oculomotor responses, was used as a control. We identified a bilateral, though mainly right-hemisphere based, fronto-parietal network involved in egocentric processing. A subset of these regions, including a much less extensive unilateral, right fronto-parietal network, was found to be active during object-based processing. The right-hemisphere lateralization and the partial superposition of the egocentric and the object-based networks is discussed in the light of neuropsychological findings in brain-damaged patients with unilateral spatial neglect and of neurophysiological studies in the monkey.
- Published
- 2000
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