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Chemical investigation of the hydnoid fungus Sarcodontia setosa resulted in the isolation of five compounds, including two new sarcodontic acid derivatives - setosic acid ( 1 ) and 7,8-dehydrohomosarcodontic acid ( 2 ) along with three known benzoquinone pigments - sarcodontic acid ( 3 ), 4,5-dehydrosarcodontic acid ( 4 ) and dihydrosarcodontic acid ( 5 ). The structures were elucidated using spectroscopic methods (UV, NMR and HR-ESIMS). The biosynthetic relationship of the isolated compounds is proposed and discussed. Antibacterial activity screening of compounds 1 - 5 against ESKAPE bacterial strains in vitro with zones of inhibition was performed and MIC values were established for the most active compounds ( 3 and 5 ).

Two undescribed ( 1 - 2) and five known cyclic diarylheptanoids ( 3 - 7 ) were isolated from the false heartwood of white birch ( Betula pubescens Ehrh.). All structures were elucidated through extensive 1D and 2D NMR experiments and HR-ESI-MS data, along with comparison of their spectroscopic data with those reported in the literature. The two new cyclic diarylheptanoids are betuladiol ( 1 ) and betulondiol ( 2 ). Extracts from false heartwood were evaluated for their antimicrobial activity against Klebsiella pneumoniae , Escherichia coli , Proteus mirabilis, Staphylococcus aureus and Cutibacterium acnes together with their antifungal activity against Candida albicans and Candida glabrata .

A new dihydrochalcone, 2',4'-dimethoxydihydrochalcone ( 1 ), together with 7 known compounds, 2',4'-dihydroxydihydrochalcone ( 2 ), 2'-hydroxy-4'-methoxydihydrochalcone ( 3 ), 2'-hydroxy-4'-methoxychalcone ( 4 ), 1-(3,5-dihydroxy-4-methoxyphenyl)-2-(3-hydroxyphenyl) ethane ( 5 ), 2,3,4,7-tetramethoxy-9,10-dihydrophenanthrene ( 6 ), 5-hydroxy-2,3,4-trimethoxy-9,10-dihydrophenanthrene ( 7 ) and 5,7-dihydroxy-6,8-dimethyl flavanone ( 8 ) were isolated from the shoots of Empetrum nigrum L. The structures of these compounds were elucidated using 1D and 2D NMR experiments along with HR-ESI-MS. Compound 6 is reported for the genus Empetrum for the first time.[Formula: see text].