1. MITOMYCIN-C INDUCED HEMOLYTIC UREMIC SYNDROME: A CASE REPORT.
- Author
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Gundappa, Rajaram K., Sud, Kamal, Kohli, Harbir S., Gupta, Krishan L., Joshi, Kusum, and Sakhuja, Vinay
- Subjects
HEMOLYTIC-uremic syndrome ,MITOMYCIN C ,ACUTE kidney failure ,CANCER - Abstract
Mitomycin-C is used widely in the treatment of malignancies and is associated with serious dose related adverse effects including the occurrence of hemolytic uremic syndrome. We report a patient with a colonic adenocarcinoma who developed hemolytic uremic syndrome after receiving 85 mg/m2 of the drug. The patient was left untreated and died 5 months after this diagnosis was made, of a second malignancy. Differential diagnosis and treatment of this condition are discussed. [ABSTRACT FROM AUTHOR]
- Published
- 2002
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