1. Prevalence of neuropsychiatric symptoms and psychotropic drug use in patients with acquired brain injury in long-term care: a systematic review.
- Author
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Kohnen, Roy F., Gerritsen, Debby L., Smals, Odile M., Lavrijsen, Jan C.M., and Koopmans, Raymond T.C.M.
- Subjects
PSYCHIATRIC diagnosis ,DIAGNOSIS of neurological disorders ,ANTICONVULSANTS ,ANTIDEPRESSANTS ,BRAIN injuries ,CINAHL database ,MENTAL depression ,DRUG utilization ,MEDICAL information storage & retrieval systems ,PSYCHOLOGY information storage & retrieval systems ,LONG-term health care ,MEDICAL care ,MEDLINE ,NURSING care facilities ,ONLINE information services ,PATIENTS ,PSYCHIATRIC drugs ,TRANQUILIZING drugs ,SYSTEMATIC reviews ,SAMPLE size (Statistics) ,DISEASE prevalence ,PSYCHOLOGY - Abstract
Objective: Little is known about the prevalence of neuropsychiatric symptoms (NPS) and psychotropic drug use (PDU) in patients below the age of 65 years with acquired brain injury (ABI) in long-term care. The objective of this study was to review the literature about the prevalence of NPS and PDU. Methods: A systematic literature search of English, Dutch and German articles in Pubmed, EMBASE, PsycINFO and CINAHL was performed with the use of MeSH and free-text terms. Results: Six articles met the inclusion criteria. The place of residence was mainly a nursing home and most studies were conducted in a population of patients with traumatic brain injury. Sample sizes varied from 40 to 26,472 residents and NPS were assessed with different assessment instruments. Depressive symptoms were most common with a prevalence ranging from 13.9% to 39.3%. Two studies reported PDU in which tranquillizers (59%) were the most prevalent psychotropic drugs followed by anticonvulsants (35%) and antidepressants (26-34%). Conclusions: Patients with ABI experience lifelong consequences, regardless the cause of ABI, that have a high impact on them and their surroundings. More insight into the magnitude of NPS and PDU, through prevalence studies, is necessary to achieve suitable provision of care for these patients. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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