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The article presents the discussion on practical fields like bioethics. Topics include addressing cutting-edge challenges like human-brain organoids, artificial intelligence (AI), and interspecies chimeras; and concern arises specifically when individuals lack intellectual capacities that Western views deem necessary for personhood, such as sentience, consciousness, autonomy, and rationality.

The author offers insights on the use and necessity of cardiopulmonary resuscitation (CPR), in response to the article "Irrational Exuberance: Cardiopulmonary Resuscitation as Fetish" by P. M. Rosoff and L. J. Schneiderman, published within the issue. Topics explored include the perception of healthcare providers, patients, and the media on CPR, the need to consider patient outcomes associated with the procedure, and the need to respect wishes and values of the patient before performing CPR.

The author comments on the study "How the Neuroscience of Decision Making Informs Our Conception of Autonomy," by Gidon Felsen and Peter Reiner. The author presents his view on the standard model of Felsen and Reiner that autonomous decision is rational and not affected by undue influence. The conclusion is that the brain performs many functions such as analyzing external influence, emotions and interactions with others in decision making.