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Cancer has been responsible for high morbidity and mortality globally. The treatment of cancer is possible using different kinds of therapies using anticancer drugs if it is diagnosed at the right time. Nevertheless, their appropriate administration for maximum therapeutic effect and their elimination from the patient's body causing environmental problems are two big issues which could be successfully abated using molecular imprinted polymers (MIPs) owing to their unique features. In this review, we have compiled and discussed the works on the determination and controlled release of anticancer drugs based on MIPs. We also highlighted the current challenges and remedies, and the future direction of MIPs in this area. [ABSTRACT FROM AUTHOR]