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Recently, we are witnessing an emerging global public health crisis with the inception and outspread of the 2019 novel Coronavirus Disease (2019-nCoV), causing respiratory illness termed as COVID-19. The COVID-19 virus is transmitted between people when they are in close proximity to each other. Preventive and mitigation measures are critical in the fight against COVID-19 disruptions. Personal Protective Equipment, also known as PPE, is a crucial effective measure against the virus. PPEs are the dedicated equipment or clothing worn by an individual for protection against infectious diseases. However, surging demand, low product quality standards, and disruptions in the global supply chain of PPEs amid the COVID-19 pandemic are putting the lives of public and frontline healthcare workers at risk. Hence it becomes crucial to retrospect the lifecycle of PPEs. This paper attempts to present a discussion of PPEs from the product lifecycle perspective, beginning at its conception, after that traversing through various stages of design and manufacturing, and then finally ending with end-of-life issues such as disposal and recycling. Additionally, we also critically outline things that went wrong recently in PPE supply chain management and propose possible productive measures for future pandemics of this nature. [ABSTRACT FROM AUTHOR]

The novel coronavirus (COVID-19) pandemic is a public health emergency of international concern that caused disaster consequences all over the world. To mitigate and manage the pandemic, geographical information systems (GIS)-based spatial analysis has been used in a key role. To this aim, many GIS-based maps are produced by many national and international institutions. However, the produced maps are prepared by conventional methods and the features in these maps representing by their areal size. This paper proposes the diffusion-based cartograms for visualization of the COVID-19 outbreak. In the study, daily country-level data of the first 150 days of the COVID-19 outbreak were obtained from WHO, and the spread and spatial patterns of the epidemic were presented according to the number of confirmed cases and deaths. As a result of the study, it was observed that the cartogram is a powerful visualization tool and superior to the classical methods. [ABSTRACT FROM AUTHOR]

The Covid-19 pandemic caused many countries to take strict measures in order to control the spread of the virus. Their goal was to protect the vulnerable groups and the health care systems from collapsing. This discussion article relies on opportunistic observations from several countries and Foucault's theory of biopower to discuss that governments attempted to control Covid-19 by monitoring large numbers of people, and that this was achieved through the construction of discourse and technologies of domination. The article further discusses that people could be better empowered in order to participate more effectively in any attempts to further manage Covid-19 and that governments should self-evaluate their strategy for responding to future pandemics. [ABSTRACT FROM AUTHOR]

In the last year, we are facing a pandemic caused by SARS-CoV-2 which causes a disease called COVID-19. In everyday practice, we encounter a number of issues related to IBD patients and COVID-19. So far, we have a lot of information regarding issues of IBD patients and COVID-19, but they are scattered across numerous scientific articles. In this review, we have made a synthesis of previous knowledge regarding the main issues such as IBD patients and risk of SARS-CoV-2infection/COVID-19, outcomes of IBD patients infected with SARS-CoV-2, treatment of IBD patients in the pandemic era, endoscopy in the pandemic era, vaccination, and patient's perception and well-being during the pandemic era. The main goal of our paper is to summarize current knowledge in this literature review. [ABSTRACT FROM AUTHOR]

Public health lessons from one pandemic become the planning assumptions for the next one. Aotearoa New Zealand's 2017 pandemic plan was derived from past experience of influenza. When Covid-19 emerged as a major global health threat, it took time for the realisation to crystallise that this infection was so different from influenza that it required a completely new pandemic response strategy. In this paper we describe how early evidence about SARS-CoV-2 transmission from China led to the adoption of an elimination strategy in Aotearoa New Zealand, making it the first country to choose elimination as a specific policy response. We discuss how further evidence has shaped the selection and design of Covid-19 pandemic control measures such as border restrictions, case and contact management, hygiene practices and use of face masks, physical distancing, and vaccines. This experience demonstrates the need for a different approach to the design of the next national pandemic plan. We identify key early evidence that will be required to develop a flexible and appropriate public health response to a new pandemic threat. We present a framework for a new pandemic plan that aims to learn from the Covid-19 experience by making as few limiting assumptions as possible. [ABSTRACT FROM AUTHOR]

The lifecycle of COVID-19 pandemic curves requires timely decisions to protect public health while minimizing the impact to global economy. New models are necessary to predict the effect of mobility suppression/reactivation decisions at a global scale. This research presents an approach to understand such tensions by modeling air travel restrictions during the new coronavirus outbreak. The paper begins with an updated review on the impact of air mobility in infectious disease progression, followed by the adoption of complex networks based on semi-supervised statistical learning. The model can be used to (1) determine the early identification of infectious disease spread via air travel and (2) align the need to keep the economy working with open connections and the different dynamic of national pandemic curves. The approach takes advantage of open data and machine self-supervised statistical learning to develop knowledge networks visualization. Test cases using Hong Kong and Wuhan aerial mobility are discussed in the decisions to (1) restrict and (2) increase mobility. The approach may also be of governments use in their international cooperation policy and commercial companies that need to choose how to prioritize the re-opening of international trade routes. [ABSTRACT FROM AUTHOR]

This paper assesses the state of COVID-19 in the Pakistani and Indian prison systems. Using publicly available data, governmental documents, media, and non-profit organization reports, and scholarly literature, we provide an overview of COVID-19 in each country and the current state of each nation's prison system. We then analyze the impact of the novel coronavirus on the corrections systems and each government's response to the virus in its prison infrastructure. The pandemic provides both Pakistan and India with the opportunity to change course and move toward a more sustainable prison system that protects human rights while bolstering health security. [ABSTRACT FROM AUTHOR]

Solid waste management (SWM) is a public health service whose importance is often understated. When the solid waste management challenge is exacerbated by a public health emergency such as the Covid-19 pandemic, its real significance as an essential service becomes more apparent. The outbreak and spread of the novel coronavirus (Covid-19) has led to dramatic transformations of every sector of the Nigerian society including SWM systems, where formal and informal actors co-exist often in an uneasy relationship. Unfortunately, strategies for inclusive management of solid wastes during and after the Covid-19 pandemic are lacking in Nigeria, fuelling the further exclusion of informal sector in the waste governance and policy process in Nigeria. This paper reviews the state of the Covid-19 pandemic in Nigeria, identifies policy gaps in solid waste governance and highlights the linkages between Covid-19 and SWM with a view to catalysing inclusive solid waste governance and sustainability policy in Nigeria. It is argued that acknowledging the informal economy is the critical first step towards framing a sustainable SWM policy in which primary stakeholders are involved. [ABSTRACT FROM AUTHOR]

The coronavirus disease (COVID-19) is a global health emergency. Major disruption to healthcare services during the current COVID-19 pandemic will last even after its peak. Sexual and reproductive health (SRH), specially contraception, needs to be understood as an essential service. This paper is a narrative review. Data from PubMed/MEDLINE, Scopus, and websites of scientific societies were screened during the months of April and May 2020. It addresses the main aspects related to contraception during the COVID-19 pandemic, with special emphasis on family planning services, extended use of long-acting reversible contraceptive (LARC) methods, drug interactions, and thromboembolism risk. We also specified some issues focused on the Brazilian reality. Ensuring proper contraception use in the COVID-19 time is very important. We encourage women, healthcare providers, policymakers, and the society to consider SRH services as priority. [ABSTRACT FROM AUTHOR]

The habit of finger-licking is an insanitary habit observed everywhere including hospital wards and other medical facilities, among providers and other staff members. It is an enduring habit that has been present before and during the pandemic and will continue unless serious notice of it is taken. Herein, we illustrate the risks imposed by this everyday habit on individuals practicing it and on surrounding people, we describe the challenges with prior attempts to defeat this habit, and we explain how the face mask can eliminate this ever-lasting habit. [ABSTRACT FROM AUTHOR]

Karur, one of the oldest towns in Tamil Nadu, a southern state in India, embedded with its rich cultural history and heritage of over more than 2000 years can be considered a key textile hub in present times. Being perennially busy with home furnishings and garment exports, like any other "Textile" town of India or other textile players of the world, Karur was pushed into lockdown one after another from March 2020 for a few undecided months owing to the pandemic outbreak of the disease Covid-19 with a new class of corona virus, known as SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) being responsible for the occurrence of this disease. With uncertainty and a lack of clarity looming over their heads, many owners with the backing of their employees of the textile firms and industries jumpstarted their lives trying their best in beating the odds laid on themselves in quite successful ways backed with technical innovations. Though it happened for few, it didn't realize for some. This paper attempts to track and research on some of the life stories of achievement and the unprecedented misery few were suddenly pushed into. While this town's success stories as a meticulous process of change in its people's mindset in desperate times toward themselves and those around can be studied to be implemented as a role model for other towns, the future lying in its unpredictability can never be ascertained thereby only making the successful solutions of those a base study of learning for the next. [ABSTRACT FROM AUTHOR]

In the wake of the COVID-19 pandemic, scholars mobilized their efforts to address its far-reaching societal problems. With mobility restrictions being front and center of the pandemic, a new cohort of transportation science was developed within a short period of time. Here, we examine more than 400 studies related to COVID-19 published across transportation journals during 2020 and 2021. The aim is (i) to scope this newly developed segment of transportation research, (ii) outline the diversity of pandemic-related issues across various divisions of the transportation field and (iii) provide a roadmap for the future of this line of research. Common themes are identified and existing congruence and discrepancies across findings are discussed. Results show that although conventional methods of transportation research were adopted in virtually all COVID-19 studies, no pre-pandemic study was particularly instrumental in the development of this segment of transportation literature. The COVID-19 segment appears to have developed its own independent knowledge foundation, in that, it does not systemically and frequently look back at any particular pre-pandemic reference. Potential impacts of this newly developed segment on the metrics of transportation journals are quantified and discussed. [ABSTRACT FROM AUTHOR]

SARS-CoV-2 has resulted in a global pandemic resulting in the infections of many millions and deaths of well over a million people. The ease of SARS-CoV-2 spread and the infectious nature of the virus in humans has resulted in an urgent need for effective disinfection strategies. Ozone (O3) is a promising disinfectant for SARS-CoV-2 due to its ability to overcome limitations with topical disinfection or sanitation products. In this work, we utilized RT-qPCR to measure RNA from a recombinant mammalian cell product, bacteriophage MS2, and SARS-CoV-2 sourced from municipal wastewater, after exposure to 4.5 and 9 ppmv O3. [ABSTRACT FROM AUTHOR]

SARS-CoV-2 has caused a worldwide pandemic that began with an outbreak of pneumonia cases in the Hubei province of China. Knowledge of those most at risk is integral for treatment, guideline implementation, and resource allocation. We conducted a systematic review and meta-analysis to evaluate comorbidities associated with severe and fatal cases of COVID-19. A search was conducted on PubMed and EmBase on 20 April 2020. Pooled estimates were collected using a random-effects model. Thirty-three studies were included in the systematic review and twenty-two in the meta-analysis. Of the total cases 40.80% (95%CI: 35.49%, 46.11%) had comorbidities, while fatal cases had 74.37% (95%CI: 55.78%, 86.97%). Hypertension was more prevalent in severe [47.65% (95%CI: 35.04%, 60.26%)] and fatal [47.90% (95%CI: 40.33%, 55.48%)] cases compared to total cases [14.34% (95%CI: 6.60%, 28.42%)]. Diabetes was more prevalent among fatal cases [24.89% (95%CI: 18.80%, 32.16%)] compared to total cases [9.65% (95%CI: 6.83%, 13.48%)]. Respiratory diseases had a higher prevalence in fatal cases [10.89% (95%CI: 7.57%, 15.43%)] in comparison to total cases [3.65% (95%CI: 2.16%, 6.1%)]. Studies assessing the mechanisms accounting for the associations between severe cases and hypertension, diabetes, and respiratory diseases are crucial in understanding this new disease, managing patients at risk, and developing policies and guidelines that will reduce future risk of severe COVID-19 disease. [ABSTRACT FROM AUTHOR]

In December 2019, the SARS-CoV-2 virus was first detected in Wuhan, China. Soon after, China became the first country in the world to enforce strict lockdown protocols in an effort to mitigate the spread of the disease. This study examines the perceptions of pandemic rules enforcement during the first COVID-19 lockdown in 2020 among 600 Chinese police officers. The analyses reveal that police departments' prompt and adequate adjustment to the pandemic, police officers' procedural justice in interacting with citizens, and police perceptions of police trustworthiness among the citizens all had direct and indirect effects on public compliance to lockdown enforcement during the pandemic. These findings affirm the role of police procedural justice in public compliance to law enforcement in China and stress the importance of organizational adjustment and public trust during an emergency situation such as the COVID-19 pandemic. Implications to pandemic-related policymaking and enforcement are also discussed. [ABSTRACT FROM AUTHOR]

We fit an SARS-CoV-2 model to US data of COVID-19 cases and deaths. We conclude that the model is not structurally identifiable. We make the model identifiable by prefixing some of the parameters from external information. Practical identifiability of the model through Monte Carlo simulations reveals that two of the parameters may not be practically identifiable. With thus identified parameters, we set up an optimal control problem with social distancing and isolation as control variables. We investigate two scenarios: the controls are applied for the entire duration and the controls are applied only for the period of time. Our results show that if the controls are applied early in the epidemic, the reduction in the infected classes is at least an order of magnitude higher compared to when controls are applied with 2-week delay. Further, removing the controls before the pandemic ends leads to rebound of the infected classes. [ABSTRACT FROM AUTHOR]

After the novel coronavirus began spreading across the U.S., many state and local governments imposed COVID-19 restrictions in an attempt to slow the spread. These COVID-19 mitigation techniques had a large impact on policing, as they created a new crime category for police to enforce, COVID-19 public health violations. The current study aims to address some of the uninvestigated questions about policing a pandemic using a unique dataset that combines three sources of official data from San Antonio, Texas. Specifically, we examine the associations between enforcement of COVID-19 public health violations, police calls for service, and COVID-19 case numbers. We also test for interactions between COVID-19 case numbers and police calls for service with respect to a change in the enforcement of COVID-19 public health violations. Results indicate that both police calls for service and COVID-19 case numbers are significantly associated with enforcement activities for COVID-19 public health violations. Additionally, enforcement is conditioned by the amount and type of police calls for service. Policymakers should consider the work and responsibilities the agencies they expect to enforce these COVID-19 policies already have. Haphazardly assigning an agency, such as the police, this new role without carefully considering whether they can feasibly take on more could lead to less enforcement of the COVID-19 restrictions. [ABSTRACT FROM AUTHOR]

Around the world, almost every aspect of people's lives has been affected by the novel coronavirus (COVID-19). We focused on one context that has received relatively little attention to date: the courtroom. Guided by established psychological findings and theories, we explored how the emergence of COVID-19 and proposed protective measures against the virus (i.e. face masks, physical distancing) could affect legal decision-making at trial. For the majority of the phenomena that we considered, the extant literature predicted negative or mixed effects. Because it appears likely that extralegal factors related to the pandemic will affect outcomes, the fairness of proceedings must be called into question. Overall, this work suggests that the reopening of the courts might be premature. It also highlights the importance of leveraging established psychological findings to address questions arising from unpredictable events when direct research is not yet available. [ABSTRACT FROM AUTHOR]

Introduction: The coronavirus disease 2019 (COVID-19) was recognized as a pandemic by the World Health Organization on March 11, 2020. As an infectious disease with no specific treatment, several measures have been established to minimize the outbreak of this disease, including social isolation. Objective: To evaluate the behavior of adolescents during the isolation period. Methods: This is a cross-sectional descriptive study conducted at the Adolescent Health Studies Center. Data were obtained from a questionnaire prepared on Google Forms, sent by a multiplatform instant messaging application, and analyzed using the Stata 14 software. Results: A total of 208 adolescents with a mean age of 15.3 years (SD ± 1.8) answered the questionnaire, 57.7% were female. About 93.3% of adolescents said they were in isolation with a changed routine, 67.3% increased their food consumption, 86.5% were inactive, and 58.7% reported screen time over 8 h/d. There was an association between anxiety and increased food consumption (odds ratio: 3.9; CI 95% 2--7.5; p¼0.00), sleeping difficulty (odds ratio: 3.6; CI 95% 1.9--6.8; p¼0.00), and conflicting family relationship (odds ratio: 5.7; CI 95% 1.6--7.8; p¼0.01). Conclusion: The study revealed that social isolation due to an infectious disease was associated with several effects on the behavior and eating behavior of adolescents, which need to be acknowledged to encourage them to lead a healthy lifestyle after the COVID-19 confinement. [ABSTRACT FROM AUTHOR]

Introduction: There has been no work that identifies the hidden or implicit normative assumptions on which participants base their views during the COVID-19 pandemic, and their reasoning and how they reach moral or ethical judgements. Our analysis focused on participants' moral values, ethical reasoning and normative positions around the transmission of SARS-CoV-2.Methods: We analyzed data from 177 semi-structured interviews across five European countries (Germany, Ireland, Italy, Switzerland and the United Kingdom) conducted in April 2020.Results: Findings are structured in four themes: ethical contention in the context of normative uncertainty; patterns of ethical deliberation when contemplating restrictions and measures to reduce viral transmission; moral judgements regarding "good" and "bad" people; using existing structures of meaning for moral reasoning and ethical judgement.Discussion: Moral tools are an integral part of people's reaction to and experience of a pandemic. 'Moral preparedness' for the next phases of this pandemic and for future pandemics will require an understanding of the moral values and normative concepts citizens use in their own decision-making. Three important elements of this preparedness are: conceptual clarity over what responsibility or respect mean in practice; better understanding of collective mindsets and how to encourage them; and a situated, rather than universalist, approach to the development of normative standards. [ABSTRACT FROM AUTHOR]

Endoscopists are at high risk of exposure and nosocomial transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 virus) when performing endoscopic procedures due to the highly aerosol generating nature of these procedures. At present, there is still no consensus among endoscopists with regards to the type of protective equipment to be worn by healthcare workers, when performing endoscopy during the coronavirus 2019 (COVID-19) pandemic. This review encompasses a summary of currently published guidelines related to the use of personal protective equipment (PPE) when performing endoscopic procedures during the COVID-19 pandemic. With increasing calls to rationalize the use of PPE due to shortages in global supply chains, the review offers a concise summary on the most appropriate and adequate use of PPE when performing endoscopy during the pandemic. It is expected that these adaptations in the use of PPE during the pandemic will help to improve standards of care and safety of healthcare workers. [ABSTRACT FROM AUTHOR]

We propose two models inspired by the COVID-19 pandemic: a coupled disease-human behaviour (or disease-game theoretic), and a coupled disease-human behaviour-economic model, both of which account for the impact of social-distancing on disease control and economic growth. The models exhibit rich dynamical behaviour including multistable equilibria, a backward bifurcation, and sustained bounded periodic oscillations. Analyses of the first model suggests that the disease can be eliminated if everybody practices full social-distancing, but the most likely outcome is some level of disease coupled with some level of social-distancing. The same outcome is observed with the second model when the economy is weaker than the social norms to follow health directives. However, if the economy is stronger, it can support some level of social-distancing that can lead to disease elimination. [ABSTRACT FROM AUTHOR]

During the SARS-CoV-2 (or Covid-19) pandemic that has plagued the world in recent months, several renowned intellectuals have spoken in academic publications and the media about the risks and expectations brought by the post-pandemic scenario, sometimes with an ethical or phenomenological-existential approach, and sometimes with a more political focus. The aim of this article is to synthesize and analyze the different positions expressed by the authors mentioned and to present some similar reflections made by Portuguese-speaking authors (from Portugal and Brazil), as well as to propose an alternative evaluation based on the critique of value and the works of Marx. [ABSTRACT FROM AUTHOR]

Countries around the world introduced strict restrictions on movement and activities known as 'lockdowns' to restrict the spread of the novel coronavirus disease (COVID-19) from the end of 2019. A sudden improvement in air quality was observed globally as a result of these lockdowns. To provide insight into the changes in air pollution levels in response to the COVID-19 restrictions we have compared surface air quality data in Delhi during four phases of lockdown and the first phase of the restriction easing period (25 March to 30 June 2020) with data from a baseline period (2018–2019). Simultaneously, short-term exposure of PM2.5 and O3 attributed premature mortality were calculated to understand the health benefit of the change in air quality. Ground–level observations in Delhi showed that concentrations of PM10, PM2.5 and NO2 dropped substantially in 2020 during the overall study period compared with the same period in previous years, with average reductions of ~49%, ~39%, and ~39%, respectively. An overall lower reduction in O3 of ~19% was observed for Delhi. A slight increase in O3 was found in Delhi's industrial and traffic regions. The highest peak of the diurnal variation decreased substantially for all the pollutants at every phase. The decrease in PM2.5 and O3 concentrations in 2020, prevented 904 total premature deaths, a 60% improvement when compared to the figures for 2018–2019. The restrictions on human activities during the lockdown have reduced anthropogenic emissions and subsequently improved air quality and human health in one of the most polluted cities in the world. Implications: I am submitting herewith the manuscript entitled "Unprecedented Reduction in Air Pollution and Corresponding Short-term Premature Mortality Associated with COVID-19 Forced Confinement in Delhi, India" for potential publishing in your journal. The novelty of this research lies in: (1) we utilized ground-level air quality data in Delhi during four phases of lockdown and the first phase of unlocking period (25th March to 30th June) for 2020 as well as data from the baseline period (2018–2019) to provide an early insight into the changes in air pollution levels in response to the COVID-19 pandemic, (2) Chatarize the change of diurnal variation of the pollutants and (3) we assess the health risk due to PM2.5 and O3. Results from ground-level observations in Delhi showed that concentrations of PM10, PM2.5 and NO2 substantially dropped in 2020 during the overall study period compared to the similar period in previous years, with an average reduction of ~49%, ~39%, and ~39%, respectively. In the case of O3, the overall reduction was observed as ~19% in Delhi, while a slight increase was found in industrial and traffic regions. And consequently, the highest peak of the diurnal variation decreased substantially for all the pollutants. The health impact assessment of the changes in air quality indicated that 904 short-term premature deaths (~60%) were prevented due to the decline in PM2.5 and O3 concentrations in the study period. The restrictions on human activities during the lockdown have reduced the anthropogenic emissions and subsequently improved air quality and human health in one of the most polluted cities in the world. [ABSTRACT FROM AUTHOR]

Governments worldwide are struggling to contain the spread of COVID-19 because many countries rely on outdated, non-digital response approaches and are thus far from exploiting the potential that digital technologies provide for pandemic response. Consequently, this study constructs a systematic approach to coordinate and manage digital pandemic response applications. To do so, the study reviews 210 peer-reviewed journal articles retrieved by querying scientific databases and searching for best-practice reports. To construct a strategic action framework, this study relies upon an organizational approach illustrating target setting and functional content in five strategic action fields. As a result, this study contributes to the current state of research by explaining how digital technology and applications may improve public pandemic response management. For practitioners, the comprehensive and action-oriented approach provides insights into the scope and the content of strategic fields of digital pandemic prevention and a roadmap to prepare digital society for pandemic outbreakes. [ABSTRACT FROM AUTHOR]

In the absence of pharmaceutical interventions for the Novel Coronavirus (COVID-19), countries have taken drastic steps like quarantine, prohibit large-scale gatherings, limited transport, social distancing, curfews, and lockdowns to curtail the spread of the virus. In light of these events, the current study attempts to understand the short-term changes in road traffic patterns, using data from two Wi-Fi MAC Scanners deployed at strategic locations in Chennai, India. The results indicate that the road traffic activities significantly reduced due to the restrictions in non-essential trips, workplace suspensions, and strict surveillance during lockdowns. However, as the lockdown rules eased, the road traffic activities began to recover. It is found that complete closedown is most effective in reducing road travel activity, but ad-hoc short duration complete closedowns may only yield temporary benefits. Also, extended lockdowns without proper enforcement may be ineffective since the public appeared to ignore the advisory after a while. [ABSTRACT FROM AUTHOR]

The COVID-19 pandemic has created a public health crisis, infected millions of people, and caused a significant number of deaths. SARS-CoV-2 transmits from person to person through several routes, mainly via respiratory droplets, which makes it difficult to contain its spread into the community. Here, we provide an overview of the epidemiology, pathogenesis, clinical presentation, diagnosis, and treatment of COVID-19. Direct person-to-person respiratory transmission has rapidly amplified the spread of coronavirus. In the absence of any clinically proven treatment options, the current clinical management of COVID-19 includes symptom management, infection prevention and control measures, optimized supportive care, and intensive care support in severe or critical illness. Developing an effective vaccine is now a leading research priority. Some vaccines have already been approved by the regulatory authorities for the prevention of COVID-19. General prevention and protection measures regarding the containment and management of the second or third waves are necessary to minimize the risk of infection. Until now, four vaccines reported variable efficacies of between 62–95%, and two of them (Pfizer/BioNTech and Moderna) received FDA emergency use authorization. Equitable access and effective distribution of these vaccines in all countries will save millions of lives. [ABSTRACT FROM AUTHOR]

The current situation across the globe has made us reflect on state and Government during emergency times. Series of questions have raised about the governance aspect of organizations associated with the management of COVID-19. Based on this context, this article argues that the idea of governance lacks human-centric values and this has impacted the functionality aspect of governance, especially at the time of the novel coronavirus outbreak. Discrepancies in different tiers of the governance system resulted in producing health-related stigmas and discriminatory behaviors toward particular sections of the population like the migrant people. It suffices the need for recasting in the concept of governance concerning pandemic. The study further taking instances from Assam based on primary and secondary sources tries to show the loopholes in state-level governance functionality in terms of providing care during the health crisis. Moreover, it will look into the possibilities of a more efficient form of governance where the potentiality of Panchayati Raj institutions (PRIs) in bringing care and trust at the community level will be explored. [ABSTRACT FROM AUTHOR]

Physical distancing (also commonly known as social distancing) is an important non-pharmaceutical strategy to minimise the risk of transmission of SARS-CoV-2 virus. A range of restrictions to promote physical distancing form a key part of the Aotearoa New Zealand (NZ) all-of-government response to the global COVID-19 pandemic. The effectiveness of physical distancing strategies is highly dependent on buy-in and the actions of individuals, households and communities. This NZ population survey was conducted to identify people's views on the effectiveness of various strategies, and factors impacting on their capacity to follow physical distancing requirements during Alert Levels 4, 3, and 2 (April 24th–June 8th 2020). The majority of the 2407 participants were supportive of the public health measures implemented to promote physical distancing across Alert Levels. Few substantial differences were observed in relation to demographic characteristics, suggesting high overall levels of understanding and willingness to adhere to distancing requirements. Around half of the participants reported difficulties practicing physical distancing when in public. Reasons included being an essential worker and challenges related to the behaviour of others. These survey findings highlight the willingness of NZ's population to play their part in eliminating COVID-19 transmission, and the way in which behavioural change was rapidly adopted in line with government requirements. [ABSTRACT FROM AUTHOR]

This article, primarily focused on Europe, charts some of the momentous transformations in bordering practices, migration and global mobility that have been sparked by the new coronavirus pandemic. In a first part it argues that since the onset of the pandemic, the enduring 'global mobility apartheid' which uses citizenship and visa restrictions to police the differential access to mobility founded on race and class, has been supplemented by a fluctuating 'sanitary apartheid', seeking to separate populations designated as at risk of Covid-19 infection from those designated as Covid-free. While these logics are distinct, where states have conflated them, we have seen eruptive and mutating border violence. In a second more normative part the article seeks to rethink the demand for freedom of movement in the context of the pandemic, arguing that allowing migrants who today are illegalised to move in safe and legal ways is also the condition to implement sanitary measures to protect the health of migrants and sedentary populations alike. Adopting a mobility justice approach, the article also argues that the excessive mobility of the privileged through air travel that has been a major factor in spreading the virus and contributes to ecological destruction should be limited. Ultimately this article calls for re-thinking the politics of (im)mobility in the context of the pandemic as part of the process of transformation towards a more just and sustainable world. [ABSTRACT FROM AUTHOR]

The sudden onset of COVID-19 has challenged many social scientists to proceed without a robust theoretical and empirical foundation upon which to build. Addressing this challenge, particularly as it pertains to Eurasia, our multinational group of scholars draws on past and ongoing research to suggest a roadmap for a new pandemic politics research subfield. Key research questions include not only how states are responding to the new coronavirus, but also reciprocal interactions between the pandemic and society, political economy, regime type, center-periphery relations, and international security. The Foucauldian concept of "biopolitics" holds out particular promise as a theoretical framework. [ABSTRACT FROM AUTHOR]

A novel coronavirus recently identified in Wuhan, China (2019-nCoV) has resulted in an increasing number of patients globally, and has become a highly lethal pathogenic member of the coronavirus family affecting humans. 2019-nCoV has established itself as one of the most threatening pandemics that human beings have faced, and therefore analysis and evaluation of all possible responses against infection is required. One such strategy includes utilizing the knowledge gained from the SARS and MERS outbreaks regarding existing antivirals. Indicating a potential for success, one of the drugs, remdesivir, under repurposing studies, has shown positive results in initial clinical studies. Therefore, in the current work, the authors have attempted to utilize the remdesivir–RdRp complex – RdRp (RNA-dependent RNA polymerase) being the putative target for remdesivir – to screen a library of the already reported RdRp inhibitor database. Further clustering on the basis of structural features and scoring refinement was performed to filter out false positive hits. Finally, molecular dynamics simulation was carried out to validate the identification of hits as RdRp inhibitors against novel coronavirus 2019-nCoV. The results yielded two putative hits which can inhibit RdRp with better potency than remdesivir, subject to further biological evaluation. [ABSTRACT FROM AUTHOR]

Although there are important examples of government offering media support, and of the media themselves responding robustly to the challenges, the overall progression has been an erosion of media power. This has had significant implications not only on the anti-regime movement, but on the state of media in general in Algeria, which I Reporters without Borders i claims has suffered government harassment of independent journalists and a gag on press freedom. Since Morocco instituted its lockdown, several journalists critical of the government have been arrested and become high-profile cases, while others already targeted by the authorities have undergone heavier surveillance. [Extracted from the article]

The lack of complete information on the immune response dynamics to infection with severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) has led to the use of mainly molecular tests such as reverse transcription PCR (RT-PCR) to diagnose Coronavirus 2019 disease (COVID-19). Although remarkable progress has been made in developing effective RT-PCR kits, the lack of specific equipment required to perform this technique in all clinical laboratories limits its widespread use. In the case of COVID-19, these tests can be used for the triage of symptomatic patients, for testing the contacts of confirmed cases, and also for the analysis and monitoring of the situation. Along with molecular tests involving reverse transcription PCR, various laboratory tests can identify the specific anti-viral antibodies or viral antigens. This review seeks to describe the targets and diagnostic methods available or currently in development for SARS-CoV-2 infection, including reverse transcription PCR (RT-PCR), serologic immunoassays (SIA) and the protein microarray method (PMM). Knowing the specific targets and the sensitivity of each assay used for COVID-19 diagnosis can lead to more efficient detection of infected patients and it can provide better management of the pandemic status. [ABSTRACT FROM AUTHOR]

The outbreak of COVID-19 caused by SARS-CoV-2 infection has become a serious hazard to global health. Apart from attacking respiratory system, it can induce multiorgan dysfunction, including cardiovascular system, liver, kidney, gastrointestinal, nervous system, and immune system. However, there are few reviews focusing on summary and comparison of diagnostic methods and complications induced by SARS-CoV-2 infection, which places a significant limit on the effective management. This review is a blend of evidence obtained by literature retrieval from PubMed, clinical experience, and the authors' opinions. We searched PubMed using the terms 'COVID-19 & diagnosis' and 'COVID-19 & complications' and selected the most relevant articles. Here we summarize the diagnostic methods that are available in clinic and discuss their different characters. Furthermore, the review offers an insight into the symptoms, incidence, and clinical strategies of complications associated with SARS-CoV-2 infection. COVID-19 has been a global pandemic, which requires rapid response. The comparison between different characters of the diagnostic methods and the summary of the symptoms, incidence, and clinical strategies of complications given in this review are not only significant for the optimal use of diagnostic methods, but also beneficial for the prevention and management of complications. [ABSTRACT FROM AUTHOR]

New Zealand's success at containing the coronavirus, despite a potential reemergence in August, is viewed by the World Health Organization as a model for handling a pandemic. This same success also appears within one of its most vulnerable locales—prisons. While New Zealand's Department of Corrections has not experienced a single COVID-19 case within prison walls, the efforts to contain the virus have also come at costs to incarcerated individuals' rights. This article demonstrates the successful efforts to contain the coronavirus pandemic in New Zealand and how these efforts have been met with both praise and criticism. In particular, we will highlight the ways in which prison officials have quickly responded to the pandemic as well as their ongoing efforts to improve the conditions for those incarcerated. [ABSTRACT FROM AUTHOR]

The COVID-19 pandemic infiltrated the United States in early 2020, with correctional facilities becoming hot spots for the novel coronavirus shortly thereafter. Using data gathered from Departments of Corrections' official websites, we provide a summary of state and federal prison system responses to COVID-19 as of June 2020. We highlight strengths and deficiencies in system responses as well as pertinent variations across jurisdictions. We conclude with a call for scholars and grant funders to prioritize incarceration-based data collection efforts on COVID-19 so the short and long-term consequences of the pandemic, and systemic responses to it, can be more fully assessed. [ABSTRACT FROM AUTHOR]

The coronavirus disease 2019 (COVID-19) pandemic has spread globally since it outbroke in December 2019. The urgent pandemic presents an unprecedented challenge to develop and identify effective medication therapy strategies to combat the COVID-19. Here, we summarized and evaluated the current treatment drugs and regimens, and put forward the treatment recommendations, including using the potential repurposed or experimental drugs against COVID-19, e.g. chloroquine (CQ), hydroxychloroquine (HCQ), lopinavir/ritonavir (LPV/r), remdesivir (RDV), and favipiravir (FPV). We also analyzed the specific drugs and vaccines against SARS-CoV-2 ongoing development and formulated the comprehensive treatment regimens based on condition of patients, diseases and drugs as well as concomitant medications. No drugs and vaccines have been proven to be particularly effective against SARS-CoV-2 up to now. The recommended comprehensive medication therapy strategies have already displayed favorable effect in the fight against COVID-19. Research should be focused on the development of anti-SARS-CoV-2 drugs and vaccines based on high-quality clinical trial evidence, treatment guidelines and expert consensus. [ABSTRACT FROM AUTHOR]

Purpose: The outbreak of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has reached pandemic proportions within an unprecedented span of time. It is controversial whether the virus can be transmitted via tears and its ocular implications have not been widely studied. In this article, the current evidence related to ocular transmission and ocular manifestations is reviewed.Results: Several mechanisms for the ocular transmission of the virus are proposed with highlight on the nasolacrimal system as a conduit between the eye and the respiratory tract, and the role of the lacrimal gland in hematogenous spread. Ocular surface manifestations such as conjunctivitis are more commonly reported.Conclusion: The exact pathophysiology of ocular transmission of the virus remains incompletely understood, although there is preliminary evidence of SARS-CoV-2 being detected in ocular secretions. The ocular tropism of the virus and its potential to cause localized ocular disease are worth considering. [ABSTRACT FROM AUTHOR]

SARS-CoV-2, the causative agent of COVID-19, represents that latest challenge in the long history of vaccine development and deployment. The pathway out of the current pandemic due to this virus requires a sufficient number of the population developing immune resistance such that herd immunity results. Finding a safe and efficacious vaccine is the most compassionate route of exit, compared to natural infection leading to unwanted fatalities of the most susceptible. As a result, vaccine acceptance might be looked on as one form of obeying the Second Great Commandment: Love thy neighbor as thyself. [ABSTRACT FROM AUTHOR]