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Purpose: In the last decades we have seen an increase in sedentary behaviors and a decrease in physical activity in children when compared to past generations. This lifestyle is commonly associated with the development of clustering risk factors that define metabolic syndrome (MetS). Knowing that motor competence (MC) development can influence lifelong physical activity habits, it is reasonable to assume that children's MC will directly link to clustered cardiometabolic health outcomes. The aim of this study was to analyze the role of MC in MetS risk factors. Methods: Seventy children with a mean age of 7.49 (SD = 1.28) years were evaluated on motor competence (MCA—Motor Competence Assessment instrument), cardiovascular fitness (PACER test), upper body strength (UBS; handgrip), and the components of MetS, hypertriglyceridemia, hypertension, abdominal obesity, low concentration of high-density lipoprotein cholesterol, and high fasting blood glucose. The composite value of MetS was calculated according to Burns et al. (2017). Multiple standard regressions were performed to explore the effect of different variables on MetS. Motor competence and health-related fitness (cardiovascular fitness and relative upper body strength) were used as independent variables (predictors) and MetS as dependent variable. Results: Overall, the results showed that motor competence (β = −.072; p <.05) is a significant predictor and this model explained 7,1% of the variance in MetS. Conclusion: Although more studies are needed, our results indicate that MC seems to have a positive role in children's health markers. This study aimed to analyze the role of MC, cardiorespiratory fitness, and upper body strength in MetS risk factors. The results suggest that upper body strength is the strongest predictor for MetS (negative association), followed by MC (positive association). When the different MC components were entered independently instead of total MC, the upper body strength and locomotor MC were found to be significant predictors of the MetS behavior. Considering our results and the fact that MC levels during childhood positively influence PA levels along lifespan, this study suggests a pathway to follow in future research. [ABSTRACT FROM AUTHOR]

Postural instability in Parkinson's disease (PD) is associated with several downstream consequences that ultimately lead to a greater risk of falling. Among the prominent downstream consequences is fear of falling (FOF), which is both common and problematic in PD. It can lead to a vicious cycle of FOF avoidance behavior that results in more sedentary behavior, physical deconditioning, and weakening of already impaired balance systems. This, in turn, may make the person with PD more susceptible to a future fall even with benign daily tasks. While FOF activity avoidance can be adaptive (appropriate), it can also be maladaptive (inappropriate or exaggerated). When this adaptive and maladaptive FOF avoidance behavior is contextualized to gait/balance performance, it provides a theoretical framework that can be used by clinicians to match patterns of behavior to a concordant treatment approach. In the theoretical framework proposed in this perspective, four different patterns related to FOF avoidance behavior and gait/balance performance are suggested: appropriate avoiders, appropriate non-avoiders, inappropriate avoiders, and inappropriate non-avoiders. For each of the four FOF avoidance behavior patterns, this paper also provides suggested treatment focuses, approaches and recommendations. [ABSTRACT FROM AUTHOR]

The aims of this study were to i) assess the relationship between COVID-19 cases with PM10 concentration and ii) investigation premature deaths due to cardiovascular (M-CVD) and respiratory (M-RD) diseases in three classification levels (PM10<50µg m−3 in normal days, 50–200 µg m−3 in dusty days, and >200 µg m−3 in MED storm), by using daily averages of PM10 concentrations. The number of M-CVD and M-RD were estimated by concentration-response model, per 105 people during 2017 to 2021. The results showed that 187, 183, 163, 215, and 206 days were observed with the PM10 concentrations lower than 50 µg m−3 during 2017 to 2021, and 178, 180, 200, 150, and 149 days were subtotal with exceeding PM10 from the WHO guideline (50 µg m−3), respectively. A positive correlation (r2=0.33, p < 0.05) was found to be between the number of COVID-19 cases and PM10 mean concentrations (r = 0.589, p = 0.046). Our findings showed that the highest M-CVD and M-RD were among exposed people at dusty days (50 < PM10≤ 200 μg m−3) in 2019. The total M-CVD and M-RD from 2017 to 2021 were 11.78 and 12.2, 18.25 and 17.4, 22.29 and 23.78, 10.33 and 7.6, 10.37 and 9.95 per 105 people, respectively which 31.48% of health effects were related to PM10 concentrations more than 200 μg m−3. [ABSTRACT FROM AUTHOR]

Engagement in physical activity (PA) during the recovery period following coronary artery bypass graft (CABG) surgery improves physical and health-related quality-of-life outcomes. To explore people's perceptions and experiences of engaging in PA during the first three months following CABG surgery. A mixed methods study design was utilized. Quantitative data were collected via accelerometer activity capture and standardized questionnaires. Qualitative data were collected via semi-structured interviews at weeks 1, 3, 6 and 12 post-hospital discharge. Interviews were analyzed using inductive thematic analysis. Two overarching themes described the overall experience of engaging in PA: 1) "Navigating a difficult and unfamiliar road to recovery" and 2) "Still cautious but becoming more confident and able." These themes described the impact over time that various physical (i.e., fatigue, pain, medical complications, and physical deconditioning), psychological (i.e., fear, confidence, uncertainty, and motivation), and environmental (support) factors had on PA engagement, as well as the relationships between these factors. The findings provided insight into the physical, psychological, and environmental factors that impacted participants' PA engagement following CABG surgery. This knowledge may benefit health professionals to optimize preparation and support for adults to engage in PA post-hospital discharge following CABG surgery. [ABSTRACT FROM AUTHOR]

Hemiparesis and physical deconditioning following stroke lead to an increase in falls, which many individuals cannot get up from. Teaching stroke survivors to independently get off the floor (IGO) might mitigate long-lie complications. IGO was taught as part of a community-based, functional rehabilitation training programme (ReTrain). We explore the feasibility of teaching IGO and assess participant's level of mastery, adherence, and injury risk. Videos of participants (n = 17) performing IGO at early, middle, and late stages of the ReTrain programme were compared to a manualised standard. A visual, qualitative analysis was used to assess technique mastery, adherence, and injury risk. Most participants (64%) achieved independent, safe practice of IGO. A good (73%) level of adherence to IGO and low incidence of risk of injury (6.8%) were observed. Deviations were made to accommodate for non-stroke related comorbidities. IGO was successfully and safely practised by stroke survivors including those with hemiparesis. Trainers should be aware of comorbidities that may impede completion of IGO and modify teaching to accommodate individual need. Further research should assess if IGO can be utilised by individuals who have other disabilities with unilateral impairments and whether IGO has physical, functional and economic benefit. Falls are common in stroke survivors, and many are unable to get up despite being uninjured, leading to long-lie complications or ambulance call-outs but non-conveyance to hospital. Teaching the independently getting up off the floor (IGO) technique to stroke survivors was possible for those with or without hemiparesis, and remained safe despite modifications to accommodate an individual's needs. Individual assessment is needed to check if a stroke survivor is suitable for learning IGO including, but not limited to, their ability to safely get to the floor and to temporarily stand (without support) at the end of the technique. [ABSTRACT FROM AUTHOR]

To analyze the feasibility of and pain-related tolerance to a maximal cardiopulmonary exercise test (CPET), and the relationship between the aerobic capacity and central sensitization (CS) in patients with chronic low back pain (CLBP). An observational study, combining a cross-sectional and a prospective 24-hour follow-up was performed. Participants underwent a maximal CPET on a cycle ergometer and were assessed with three measures of CS (CS Inventory, quantitative sensory testing and heart rate variability). Before the CPET, immediately afterwards and 24 h after, the Pain Response Questionnaire (PRQ) was filled out. The CPET was considered feasible when >80% performed maximally, and tolerable when <20% reported relevant pain increase, body reactions and additional pain medication use in the PRQ. Multiple regression analyses were applied to assess the relationship between the aerobic capacity (VO2max) and CS measures, corrected for confounders. 74 patients with CLBP participated of which 30 were male, mean age was 40.4 years (SD: 12.4) and median VO2max was 23.9 ml/kg/min (IQR: 18.2–29.4). CPET was completed by 92%. No serious adverse events occurred. A relevant pain increase was reported in the upper legs by 40% immediately after CPET and by 28% 24 h afterwards, 27% reported body reactions after 24 h, and 22% increased pain medication use 24 h after CPET. Very weak and not significant relations (rpartial=−0.21 to 0.05; p > 0.10) were observed between aerobic capacity and CS measures. A maximal CPET is feasible in patients with CLBP. Most, but not all, tolerated it well. CS was not related to aerobic capacity. Maximal CPET is feasible in patients with CLBP and well tolerated by most patients. Maximal CPET can be safely applied to assess the aerobic capacity of patients with CLBP. Aerobic capacity is unrelated to central sensitization. Outcomes of a maximal CPET and the pain response to straining activity can be used to provide valid information for the decision-making of exercise therapy. [ABSTRACT FROM AUTHOR]

Diagnostic accuracy studies are important to identify the best set of defining characteristics for a given nursing diagnosis. The reliability of nursing inferences can be increased by using clinical indicators with high prediction capacity helping nurses to be more accurate in their clinical practice. To clinically validate the nursing diagnosis Decreased diversional activity engagement in adult patients with diabetes. A diagnostic accuracy study with a cross-sectional design was carried out patients with type 2 diabetes. A latent class model with random effects was used to measure the sensitivity and specificity. The diagnosis of Decreased diversional activity engagement was present in 62.2% of the patients. The defining characteristics with high sensitivity (good indicators for confirmation) were discontent with situation, physical deconditioning, and altertion in mood. Boredom, flat affect, discontent with situation, and frequent naps were the defining characteristics with the highest specificity values. These factors are considered good integrating components of the diagnosis under investigation in patients with diabetes. The nursing diagnosis decreased diversional activity engagement is frequent in patients with diabetes, and discontent with situation can be considered a good predictor of its occurrence due to its high values of specificity and sensitivity. The use of accurate clinical indicators in the diagnostic reasoning of nurses contributes to the achievement of outcomes centered on the patient's human responses. [ABSTRACT FROM AUTHOR]

The aim of this study was to analyse the detraining process that occurs during a season break, and its influence on the performance, anthropometrics, and biomechanics of young swimmers. The sample included 54 young swimmers (22 boys: 12.79 ± 0.71 years; 32 girls: 11.78 ± 0.85 years). Performance for the 100 m freestyle and anthropometric and biomechanical variables were evaluated as main determinants. Performance impaired significantly for boys (2.17%) and girls (1.91%). All anthropometric variables increased between moments of assessment for boys and girls. Overall, the boys enhanced all biomechanical variables during the detraining period, and girls showed mixed results. For both sexes, the stroke index was the variable with the highest increase (boys: Δ = 16.16%; d = 0.89; p = 0.001; girls: Δ = 19.51%; d = 1.06; p = 0.002). Hierarchical linear modelling showed that the height retained the amount of impairment in the performance. One unit of increase in the height (cm) led to less 0.41 s impairment in the performance. Present data indicated that during an 11-weeks detraining period, young swimmers impaired their performance, but the determinant factors showed an impaired relationship. This increase in the determinant factors is mainly related to the increase in the swimmers' anthropometrics. Moreover, the increase in height was responsible for retaining the performance impairment. [ABSTRACT FROM AUTHOR]

The objective of this study is to explore the transcriptomic and biologic variables characterizing the longitudinal rehabilitation intervention of patients with hospital-acquired deconditioning (HAD). This prospective clinical trial recruited HAD patients (n = 10) who spent ≥3 weeks hospitalized and then received inpatient rehabilitation. Functional improvement was measured using the Functional Independence Measure (FIM). Transcriptomic and biological variables were recorded at rehabilitation admission and 1, 2, 4, and 6 weeks post-admission. RNA sequencing studied the temporal changes of gene expression in leukocytes. Between-subject transcriptome comparisons were performed using principle component analysis. Within-subject changes in gene expression were analyzed using a gene ontology hierarchical clustering to identify common biological terms. Heart rate, weight, albumin, creatinine, and complete blood counts were analyzed. Patients average age was 50.6 ± 7.2, FIM increased during inpatient rehabilitation (p = 0.01), weight increased (p = 0.01), lymphocytes decreased (p = 0.05), neutrophil increased (0.03) and red cell distribution width decreased (p = 0.05). The temporal profiles of gene expression revealed within-patient homogeneity and between-patients heterogeneity. The biological terms "bone morphogenesis" and "muscle cell development" were the most significantly enriched differentially expressed genes. Transcriptomic and biologic markers paralleled the functional improvements of HAD patients during inpatient rehabilitation. Transcriptomic analyses were consistent with the cohort heterogeneity. Enrichment of the biological pathways bone morphogenesis and muscle cell development constituted evidence at the gene expression level of the effect of rehabilitation. Larger studies of various rehabilitation patient groups may increase gene expression profile homogeneity. Objective transcriptomic and biologic markers have the potential to improve the rehabilitation of HAD patients. Novel gene expression methods are increasingly being integrated into clinical practice and may apply to rehabilitation. Patients with hospital-acquired deconditioning (HAD) enriched gene expression of pathways targeted by inpatient rehabilitation such as bone morphogenesis and muscle cell development. The gene expression paralleled functional improvement of HAD patients. These data demonstrated the feasibility of molecular methods to identify markers of rehabilitation success in HAD patients. [ABSTRACT FROM AUTHOR]

We evaluated cardiovascular autonomic reflexes and serum fibroblast growth factor 21 (FGF21), a surrogate marker of mitochondrial function, in a cohort of overweight and normal-weight adults (n = 42). Indices of autonomic function were monitored during supine rest, autonomic reflex tests and submaximal clinical exercise test, with heart rate variables and blood pressure measured with an automatic system. Markers of sympathetic dominance were accentuated in overweight adults, including elevated resting low-frequency to the high-frequency ratio for heart rate variability (203 ± 227 vs. 96 ± 42; p =.01), and handgrip diastolic blood pressure (36 ± 15 mmHg vs. 25 ± 12 mmHg; p =.01). A weak non-significant trend has been found for a negative correlation between blood pressure responses to isometric handgrip test and FGF21 in the overweight group (r = −0.37; p =.09). Excess body weight appears to trigger sympathetic overactivity in overweight adults, yet autonomic dysregulation might not be associated with notable changes in serum FGF21. [ABSTRACT FROM AUTHOR]

Synchronization to periodic cues such as food/water availability and light/dark cycles is crucial for living organisms' homeostasis. Both factors have been heavily influenced by human activity, with artificial light at night (ALAN) being an evolutionary challenge imposed over roughly the last century. Evidence from studies in humans and animal models shows that overt circadian misalignment, such as that imposed to about 20% of the workforce by night shift work (NSW), negatively impinges on the internal temporal order of endocrinology, physiology, metabolism, and behavior. Moreover, NSW is often associated to mistimed feeding, with both unnatural behaviors being known to increase the risk of chronic diseases, such as eating disorders, overweight, obesity, cardiovascular, metabolic (particularly type 2 diabetes mellitus) and gastrointestinal disorders, some types of cancer, as well as mental disease including sleep disturbances, cognitive disorders, and depression. Regarding deleterious effects of ALAN on reproduction, increased risk of miscarriage, preterm delivery and low birth weight have been reported in shift-worker women. These mounting lines of evidence prompt further efforts to advance our understanding of the effects of long-term NSW on health. Emerging data suggest that NSW with or without mistimed feeding modify gene expression and functional readouts in different tissues/organs, which seem to translate into persistent cardiometabolic and endocrine dysfunction. However, this research avenue still faces multiple challenges, such as functional characterization of new experimental models more closely resembling human long-term NSW and mistimed feeding in males versus females; studying further target organs; identifying molecular changes by means of deep multi-omics analyses; and exploring biomarkers of NSW with translational medicine potential. Using high-throughput and systems biology is a relatively new approach to study NSW, aimed to generate experiments addressing new biological factors, pathways, and mechanisms, going beyond the boundaries of the circadian clock molecular machinery. [ABSTRACT FROM AUTHOR]

Cardiovascular disease (CVD) is the leading cause of death in the United States and globally. The social and biological differences in diet patterns among men and women may play a role in their differential cardiovascular risk. To describe the dietary patterns associated with CVD risk and investigate the differences in diet patterns between men and women, if these differences affect cardiovascular risk, and to explore potential mechanisms of action. Diet patterns associated with CVD risk were described based on epidemiological and experimental trials. Observational and experimental studies together with systematic and non-systematic reviews were synthesised to examine sex differences in diet and cardiovascular risk factors. Differences in vasculature and body composition between sexes may be mediated by dissimilarities in adherence to diet patterns and nutrient metabolism. Salt sensitivity and breakdown and storage of lipids may account for some differences in CVD risk between men and women. Sex differences in social norms, cognitive processing, and odour perception may be affected by biological differences and contribute to differences in cardiovascular risk and dietary patterns. The relation between diet patterns and cardiovascular risk is well-established and sex differences in diet patterns likely differentially affect CVD risk between men and women. [ABSTRACT FROM AUTHOR]

The purpose of this study was to investigate the effect of a 12-week strength training, and 3 months of detraining on physical fitness, body composition, and quality of life. Methods: Twenty women underwent assessments pre- and post-training, and after cessation of training. The measurements included waist-to-hip ratio, muscle mass, fat mass, leg press and seated row strength, functional fitness (SFT), and quality of life physical component score (PCS) and mental component score (MCS). Results: Significant interaction (p < 0.01) was found in all tests except for the PCS. The subjects in the EX group significantly improved in all tests (p < 0.01) from pre- to post-training. However, during the detraining, strength, SFT, and MSC significantly worsened from post- to detraining (p < 0.01). Body composition, except for muscle mass, remained unchanged. Conclusions: It seems that body composition persists for prolonged times, compared to performance characteristics. However, the results should be interpreted with caution, because improvements in body composition had small effects (g = ∼0.20–0.32). [ABSTRACT FROM AUTHOR]

To investigate the predictive factors associated with physical impairment among older patients with type 2 diabetes mellitus (T2DM) in Japan and to examine the potential impact of physical impairment on patient-reported health outcomes in this population. A cross-sectional analysis was conducted using patient-reported data from the 2012–2014 Japan National Health and Wellness Survey. Physical impairment was measured using the Physical Component Summary (PCS) score of the Short-Form 36-Item Health Survey (SF-36) three-component model (using Japanese norms). Older T2DM patients (≥65 years old; n = 1511) were dichotomized into physically impaired (PCS ≤ 25th percentile; n = 378) and non-physically impaired (PCS > 25th percentile; n = 1133). Work productivity (absenteeism, presenteeism and overall work impairment), activity impairment and healthcare resource utilization were compared between these groups. Age, female sex, low and high body mass index (BMI), diabetes-related complications, cardiovascular events, unawareness of having hypoglycemic events in the past 3 months, and lack of regular exercise were significant factors associated with physical impairment in multivariable analysis. The physically impaired group reported significantly more regular outpatient visits (13.48 vs. 10.16, respectively, p <.001), 1% or greater absenteeism (16.7% vs. 4.1%, p =.005), greater presenteeism (27.8% vs. 12.2%, p =.001), overall work impairment (30.0% vs. 13.0%, p =.001) and overall activity impairment (39.5% vs. 17.2%, p <.001) than the non-physically-impaired group after adjusting for covariates. This study identified age, BMI, diabetes-related comorbidities, history of cardiovascular events and lack of exercise as key predictors associated with physical impairment in older patients with T2DM in Japan, which predicted low work productivity as well as activity impairment. This study provides support that physical impairment in patients with T2DM may lead to low work productivity and activity impairment. Supplemental data for this article is available online at . [ABSTRACT FROM AUTHOR]

Social jetlag (SJL) is defined as the discrepancy between social and biological rhythms and calculated by the difference between the midpoint of sleep time on working-days and free-days. Previous human and mouse studies showed SJL is positively related to evening chronotype and significantly related to smoking habit, cardiovascular risk, cognitive ability, and that SJL-mimicking conditions, simulating the real lifestyle situation of SJL in many humans, disrupt the regularity of estrous cycles of female animals. The effects of SJL-mimicking conditions on circadian rhythms and cognitive function and the reasons why the discrepancy between social and biological rhythms is involved in SJL have not yet been investigated. Therefore, in this study, we utilized a mouse model of SJL-mimicking conditions – 6-hour delayed-light/dark (LD) conditions for 2 days and normal-LD conditions for the following 5 days – applied for several weeks during which biological rhythms were monitored. Circadian rhythms of central and peripheral clocks and metabolism of the mice under the SJL-mimicking condition were always delayed for 2–3 hours compared with those under the normal-LD condition. Moreover, SJL-mimicking conditions impaired their cognitive function using a novel object recognition test. Only the delayed timing of either the light phase of the LD or of feeding for 2 days, comparable to the free-days situation of humans, delayed the circadian staging of rhythms the following 5 days. Furthermore, sleep deprivation during the early mornings for 5 days, which is comparable to early rise times experienced by humans on working-days and does affect the staging of circadian rhythms (circadian misalignment schedule), delayed the locomotor activity rhythms the next 2 days, comparable to free-days in humans, which is similar to the lifestyle rhythm of the evening chronotype. Our results demonstrated that the circadian misalignment schedule for 5 days changed the locomotor activity rhythms the following 2 days to the evening chronotype, that light- and/or feeding-shift conditions for 2 days exacerbate SJL, and that SJL-mimicking conditions delay the metabolic rhythm and cause cognitive impairment. [ABSTRACT FROM AUTHOR]

Lymphoma treatments can produce adverse effects leading to a reduced quality-of-life (QoL). Besides, in patients ≥65years, it can promote an accelerated geriatric decay. We conducted a prospective study on supervised Exercise-Training (ET), in consecutive, patients aged 18–80years, during anti-lymphoma treatments.16/30 (53%), median-age = 65.5y, participated to the ET sessions, this was the Interventional Group (IG); 14/30 (47%), median-age = 63y, were the Reference Group (RG). Both groups participated to the fitness and the QoL assessments, at baseline (T0), 3-months (T1) and 6-months (T2) after the start of chemotherapy. The adherence to the ET program was 50% (95% CI:36–64%). The IG showed substantial improvements compared to the CG in cardiorespiratory fitness (Cooper test) at both T1 and T2 and in all the functional domain of the QoL questionnaire (QLQ-C30) at T2. This study showed ET, during chemotherapy, is feasible and safe, even in patients ≥65 years. Furthermore, it may improve the provision of care. [ABSTRACT FROM AUTHOR]

The aims of this study were to investigate changes in selected performance measures during an off-season period, their association, and the potential role of age and previous hamstring injury in semi-professional and amateur football players. Seventy-four male players (age: 25 ± 4 years, stature: 178.0 ± 6.6 cm, body mass: 74.9 ± 8.1 kg) were assessed at the beginning and end of the off-season summer-period for sprint, change-of-direction performance and eccentric hamstring strength. Small to medium increases in sprint times were observed at 5 (d = 0.26, p = 0.057), 10 (d = 0.42, p < 0.001) and 30 m (d = 0.64, p < 0.001). Small (d = −0.23, p = 0.033) improvements were observed for COD performance, and no changes in eccentric hamstring strength (d = 0.10, p = 0.317). The changes in the outcomes were not affected by age (p = 0.449 to 0.928) or previous hamstring injury (p = 0.109 to 0.995). The impaired sprint performance was not related to changes in eccentric hamstring strength (r = −0.21 to 0.03, p = 0.213 to 0.856), instead, changes in COD performance were associated with changes in eccentric hamstring strength (r = −0.42, p = 0.008). [ABSTRACT FROM AUTHOR]

This study investigated the association between exercise and cardiovascular load in Korean mail carriers with high occupational physical activity (OPA). A total of 36 subjects completed a questionnaire, and their heart rates were measured for 3 consecutive days. Treadmill tests were used determine maximal oxygen uptake (VO2max). The subjects' relative heart rate (RHR) was 25.6%±4.5%, which was higher than the recommended RHR (24.5%). Daily working hours were 11.1 ± 0.9 hours, which was longer than the maximum acceptable work time (7.8 ± 1.7 hours). Multiple regression analysis showed that daily working hours were positively associated with RHR, but exercise did not show any significant association. According to the results of this study, exercise may not be of benefit to workers with high OPA, suggesting that exercise should be cautiously considered for workers with high OPA. [ABSTRACT FROM AUTHOR]

Just as increases occurring in performance during the physical exercise period continue to be a topic of research, how long elderly individuals preserve these increases are also researched. The aim of this research is to investigate changes occurring in physical fitness of older adults in the exercise, detraining and retraining periods. The first period of the research included 15 elderly individuals (11 female, 4 male) with mean age 70.5 ± 4.35 15 years, 163 ± 11 cm height, and 68.5 ± 10.8 kg. In the second period, 13 older adults (9 female, 4 male) participated with mean age 70.1 ± 3.28 years, 161 ± 0.08 cm height and 78.8 ± 10.9 kg. Older adults participated in regular multicomponent exercise 2 days per week. The Senior Fitness Test (SFT) battery for older adults was used to assess functional fitness. Exercises were completed for 6 months and then there was a break of 5 months. The detraining effect was investigated. Five months later the second exercise period continued for 6 months. A multivariate analysis of variance (ANOVA) was used to identify significant differences between the first year and second year. There were significant differences in the physical fitness parameters of leg strength. [ABSTRACT FROM AUTHOR]

Purpose: To examine the efficacy of an occupational therapy activity pacing intervention with deconditioned older adults in rehabilitation. Method: Randomised, single-blind controlled trial of deconditioned older adults admitted for rehabilitation following treatment of an acute medical condition, allocated to intervention [n = 51, males = 14, mean age = 80(8)] or control [n = 49, males = 12, mean age = 81(7)] group. The intervention group received individual and group activity pacing education with practice and application of techniques to daily activities and the home environment, while the control group received a typical occupational therapy program, which included brief activity pacing education. Outcomes included participation in daily living skills, health status (including pain and fatigue symptoms), self-efficacy in daily activities and activity pacing techniques using the Australian Therapy Outcome Measures-Occupational Therapy (AusTOMs-OT), Short Form-36 Health Survey (SF-36), Self-Efficacy Gauge and Activity Pacing Assessment. Results: No differences in groups at admission. Comparison at discharge and three months post discharge using 2 × 2 mixed ANOVA demonstrated small differences in only one scale of the activity limitation domain of the AusTOMs-OT. No significant differences were found in other scales or domains of the AusTOMs-OT, nor secondary outcome measures. Conclusion: Activity pacing in addition to typical occupational therapy during inpatient rehabilitation did not demonstrate benefits to participants in the management of their daily activities on returning home post hospitalisation. Activity pacing has been identified as one of the commonly used occupational therapy interventions utilised with deconditioned older adults in rehabilitation. An activity pacing intervention in conjunction with typical occupational therapy demonstrated no benefits for deconditioned older adults over typical occupational therapy which included basic education on this topic. Continuation of the activity pacing intervention into the outpatient setting may be of benefit to older adults and requires further investigation. [ABSTRACT FROM AUTHOR]

Virtual reality has taken many great strides in the recent years. It is increasingly used and is an accepted means of delivering behavioral therapy for phobias and anxiety disorders. In this paper, we examine methods of virtual reality stress induction for use in treatment of somatoform and anxiety disorders, as well as the adequate measures of the evoked stress response. In total, 42 healthy subjects took part in testing as part of this study. The results show that electrodermal activity is more sensitive in capturing a subject reaction to non-interactive social environment simulation while cardiovascular parameters better reflect task-related stress. Furthermore, our results suggest a distinct relationship between electrodermal activity and anxiety and cardiovascular parameters and somatoform dissociation. These results can point to a possibility of virtual reality utilization in the research and treatment of disorders in which anxiety and somatization are important features. [ABSTRACT FROM AUTHOR]

People in polluted communities are often exposed to both PM and ozone (O3), albeit not always simultaneously; an important question is whether exposure to particles with seasonal compositional differences can influence biological outcomes. We addressed this question using a mouse model of cardiovascular disease by contrasting the health outcomes of exposures to particles formed or aged during periods of relatively high photochemical activity (i.e. spring/summer), which has increased ambient O3 concentrations, with outcomes of exposures to fall/winter particles which are associated with lower O3 concentrations. Electrocardiographs (ECGs) and blood pressures (BPs) were acquired following exposures to concentrated ambient particles (CAPs). ECGs were analyzed to changes in specific waveform parameters and changes in heart rate variability (HRV). Exposures elicited several types of waveform abnormalities that were associated with seasonal differences in particle constituents. Alterations in R-R interval and P-R interval were seen following exposure to summer CAPs but not fall CAPs and differential responses were seen in the corrected Q-T interval following the two seasonal exposures. Measures of HRV increased after exposure to summer CAPs compared to air-exposed controls but not following the winter CAPs exposure. There were chemical differences with respect to the organic constituents in ambient particles between summer and fall aerosol. The oxygen to carbon ratios (O:C) were generally higher in the spring and summer than in the fall, consistent with seasonal differences in atmospheric photochemical activity. Seasonal differences in atmospheric photochemical activity can modify ambient aerosol composition and can alter biological responses in the cardiovascular system. The results from this study confirm that ambient photochemical activity can alter the toxicity of ambient PM. Regional and seasonal differences in PM2.5 composition should be important considerations when evaluating the effects of PM exposure on cardiovascular health. Implications: Particles formed during periods of high photochemical activity (e.g. spring/summer) elicit more adverse cardiovascular health effects than particles formed during periods of low photochemical activity (e.g. fall/winter). Seasonal differences in atmospheric photochemical activity modified ambient aerosol composition and worsened cardiovascular responses. These results can inform regulatory agencies and may help design air quality regulations for PM2.5 that consider seasonal and regional variations. [ABSTRACT FROM AUTHOR]

Objective: To examine the effect of cardiovascular fitness, i.e. VO2max, on the relationship between weight status and resting testosterone level (RTL) in males. Materials and methods: A subset of male participants from the 2003–2004 National Health and Nutrition Examination Survey were analyzed by weight status, i.e. normal, overweight, obese, and all participants. Bivariate correlation coefficients were computed for RTL, percent body fat (BF%), and VO2max. Partial correlation coefficients were computed between RTL and BF% controlling for VO2max and between RTL and VO2max controlling for BF%. Results: Bivariate correlations between RTL and BF%, and RTL and VO2max were significant in all groups. The partial correlation coefficients between RTL and BF% controlling for VO2max were significant in the normal and all participants group. When RTL and VO2max were analyzed controlling for BF% only the all participants group remained significant. Conclusion: Cardiovascular fitness or weight status may independently influence RTL in males. [ABSTRACT FROM AUTHOR]

Overweight and inadequate physical fitness are critical variables that impact directly on the health, wellbeing of service members and military readiness, characteristics required to overcome dangerous situations during sea rescues and in the first line of combat in the Mexican Navy. Here we determined the impact of body composition (BC) on physical fitness components (PFC) [cardiorespiratory fitness (CRF) and muscle strength-resistance (MSR)] of 110 marines, rescue swimmers, and divers of the Mexican Navy classified as overweight. We found significant differences in medians of BC and PFC among groups (p < 0.001). The WHO and military BMI showed 59 (54%) and 16 (15%) individuals as overweight, respectively. All groups showed CRF adequate for their age, but only 26 (51%) and 14 (24%) classified as normal and overweight (WHO), respectively, had adequate CFR (METs ˃12) (p = 0.003) for physical demands of military tasks. BMI in overweight at expenses of high BFP, without cardiovascular risk represents an operational task advantage that will lead to reach the balance between physical fitness, health, and military readiness. [ABSTRACT FROM AUTHOR]

Purpose: To evaluate vascular function and its relationship to cardiorespiratory fitness in professional handball athletes. Method: We examined 30 male professional handball athletes (age 27 ± 4 y) and 10 male sedentary controls (age 26 ± 5 y) at rest. The workup included exercise testing via ergometry. To assess vascular function, a validated electronic model of the arterial tree (vasc assist 2®) was used. It replicates noninvasively acquired pulse pressure waves by modulating the relevant functional parameters of compliance, resistance, inertia, pressure, and flow. The maximum oxygen uptake (VO2max) was estimated using the validated heart rate ratio method. Results: Athletes had a significantly lower systolic and diastolic central blood pressure (cBP) compared to controls (102 ± 9/60 ± 9 vs. 110 ± 8/74 ± 9 mmHg, p < .01), whereas aortic pulse wave velocity (PWV) (6.2 ± 0.8 vs. 6.3 ± 0.5 m/s, p = .45) and augmentation index at a heart rate of 75 (Aix@75) (-4 ± 12 vs. -13 ± 16%, p = .06) were not different. Resistance index (R) (15.9 ± 4.4 vs. 10.6 ± 0.6, p = .001) and maximum power output (MPO) (3.55 ± 0.54 vs. 2.46 ± 0.55 Watt/kg, p < .001) were significantly higher in athletes compared to controls. We found no relevant correlation between MPO, resting heart rate, PWV, Aix@75, and cBP. A higher VO2max (p = .02) and a lower R (p < .01) were significant predictors of a higher MPO in athletes. Conclusion: R had an independent and strong correlation to MPO in athletes, which might help to disentangle the contribution of aerobic capacity and arterial function to physical power. [ABSTRACT FROM AUTHOR]

Purpose: This study aims to analyze changes in Maximum Inspiratory Pressure (MIP), lung function, cardiorespiratory fitness, and blood pressure, in 10 healthy active elderly women, following 7 weeks of inspiratory muscle training (IMT) combined with a multicomponent training program (MCTP). The association among these health parameters, their changes after training (deltas), and the influence of MIP at baseline (MIPpre) are also considered. Methods: IMT involved 30 inspirations at 50% of the MIP, twice daily, 7 days a week, while MCTP was 1 hr, twice a week. MIP, lung function (FVC, FEV1, FEV1/FVC, FEF25-75%, PEF), 6MWT, and blood pressure (SBP, DBP), jointly with body composition, were assessed before and after the intervention. Results: Seven weeks were enough to improved MIP (p = .019; d = 1.397), 6MWT (p = .012; d = .832), SBP (p = .003; d = 1.035) and DBP (p = .024; d = .848). Despite the high physical fitness (VO2 peak: M = 23.38, SD = 3.39 ml·min·Kg-1), MIPpre was low (M = 39.00, SD = 7.63 cmH2O) and displayed a significant negative correlation with ΔMIPpre-post (r = -.821; p < .004), showing that women who started the intervention with lower MIP achieved higher improvements in inspiratory muscle strength after training. Conclusions: No significant changes in spirometric parameters may signal that lung function is independent of early improvements in inspiratory muscles and cardiorespiratory fitness. Absence of correlation between physical fitness and respiratory outcomes suggests that being fit does not ensure cardiorespiratory health in active elderly women, so IMT might be beneficial and should supplement the MCTP in this population. [ABSTRACT FROM AUTHOR]

Purpose: Community-based exercise can support long-term management of Parkinson's disease, although it is not known if personal goals are met in these programs. The objectives of this study were to: (1) examine the goals of community based exercise programs from the participant and instructor perspectives; (2) establish the extent to which these programs meet self-described exercise outcomes; and (3) explore participant and instructor perspectives on barriers to meeting exercise expectations. Materials and Methods: This study explores the experiences of people with Parkinson's disease participating in a structured exercise program at six community sites. A mixed-methods approach was used, including participant and instructor interviews, assessment of exercise intensity, and mapping of exercise dosage to participant goals. Twenty-four exercise participants provided interview, quality of life, and exercise intensity data. Results: Twenty-one participants exercised for primary management of their Parkinson's disease. None met the exercise dosage necessary to meet this primary objective, although 60% met exercise dosage required to prevent disuse deconditioning. Participants and instructors did not describe similar goals for the community-based exercise program. Conclusions: Community-based exercise programs could be optimized by better aligning participant goals and exercise intensity. [ABSTRACT FROM AUTHOR]

Purpose: This study aimed to investigate the relationship between fundamental movement skills (FMS) and markers of health among a cohort of Irish primary school children.Methods: Participants (N = 296, mean age: 7.99 ± 2.02 years) were senior infant (n = 149, mean age: 6.02 ± 0.39 years) and 4th class (n = 147, mean age: 9.97 ± 0.40 years) students from three primary schools in Cork, Ireland. FMS proficiency (TGMD-2) and markers of health (BMI percentile, waist circumference percentile, blood pressure percentiles, resting heart rate, cardiorespiratory fitness, objectively measured physical activity; PA) measurements were recorded. Correlation and hierarchical stepwise multiple linear regression analyses were conducted to investigate the relationship between FMS and markers of health.Results: A small, positive relationship was found between FMS (Gross Motor Quotient; GMQ) and cardiorespiratory fitness with small negative correlations between GMQ and 550 m time SDS among 6-year-olds (r(129) = -.286, p < .05) and 10-year-olds (r(132) = -.340, p < .05). A moderate, positive correlation was found between GMQ and light PA (r(71) = .400, p < .05). Small positive correlations were revealed between GMQ and moderate PA (r(71) = .259, p < .05) and between GMQ and total PA (r(71) = .355, p < .05). After adjusting for age, sex, the interaction effect of age and sex, and school attended, FMS explained 15.9% and 24.8% of the variance in 550 m time SDS among 6- and 10-year-olds, respectively, and 6% and 6.5% of the variance in light PA and moderate PA, respectively. After adjusting for age and sex, FMS explained 11.6% of the variance in total PA.Conclusion: A wide range of FMS is important for children's cardiorespiratory fitness and PA. [ABSTRACT FROM AUTHOR]

With the detrimental relationship between school burnout and physiological and cognitive functioning now well documented, interventions to ameliorate school burnout symptomology are needed. This study examined the effectiveness of a self-regulatory biofeedback intervention program (Heart Rate Variability Coherence Biofeedback Training [HRVCB]) in contrast to a protocol demonstrated to produce cognitive and physiological improvements (a high intensity interval training protocol [HIIT]) as well as a wait-list control condition at decreasing school burnout in an American collegiate sample (N = 90). Intervention training was conducted over a 4-week span (three sessions per week) with accompanying baseline and post-intervention assessments. In addition to measurements of school burnout and negative affect (depression and anxiety), intervention influences on cognition (via a serial subtraction task) and physiology (hemodynamics, electrocardiography, and a submaximal cardiorespiratory fitness test) were explored. Findings indicate HRVCB training significantly decreased school burnout and increased mathematical performance from pre- to post-intervention measurement. These changes did not occur for HIIT or waitlist participants. Brachial and aortic systolic blood pressure decreased pre to post-intervention for HRVCB but not HIIT or waitlist participants. Cardiovascular fitness (VO2max) improved pre to post-intervention for HIIT but not HRVCB or waitlist participants. Also, both HRVCB and HIIT training participants decreased heart rate from pre to post-intervention but not waitlist participants. Finally, all participants decreased cardiac sympathovagal tone from pre to post-intervention. These findings provide evidence that HRVCB training programs can decrease school burnout as well as improve components associated with cardiac health. Study limitations and directions for future research are discussed. [ABSTRACT FROM AUTHOR]

Cardiorespiratory fitness (CRF) is positively associated with enhanced cardiovascular health. This cross-sectional study aimed to determine associations between CRF and the biochemical profile of overweight/obese adults diagnosed with primary hypertension (HTN). Does cardiorespiratory fitness (exposure) positively affect the biochemical profile (outcome) in overweight/obese individuals suffering from HTN? Assessment with anthropometric, ambulatory blood pressure monitoring (24 h), CRF (peak oxygen uptake, V̇O2peak) and biochemical analysis was performed on 214 participants (138 men, 76 women). A series of linear and logistic regression analyses were conducted. Participants were divided into CRF tertiles (classified as low, moderate and high CRF). The CRF was independently and inversely associated with aspartate aminotransferase (AST; β = -0.328, p < .05) and alanine aminotransferase (ALT; β = -0.376, p < .01) concentrations. C-reactive protein, AST/ALT ratio, gamma-glutamyl transpeptidase, total cholesterol/high-density lipoprotein cholesterol ratio, glucose, insulin and insulin resistance index (HOMA-IR), were all associated, but not independently, with CRF in linear and/or unadjusted logistic regression models. However, independently, logistic regression revealed that glucose was associated with the moderate CRF group. Findings suggest that a lower CRF is associated with an unhealthy biochemical profile in non-physically active and overweight/obese individuals with HTN. As such, this population should look to increase physical activity in order to improve their CRF and biochemical profile. [ABSTRACT FROM AUTHOR]

We surveyed self-reported lifetime health conditions (using National Health and Aging Trends Study questions) and related driving reduction in a large multi-site older driver cohort (n = 2990) from the AAA Longitudinal Research on Aging Drivers (LongROAD) Study's baseline assessment. Those reporting reduced driving (n = 337) largely attributed reduction to musculoskeletal (29%), neurologic (13%), and ophthalmologic (10%) conditions. Women reported health condition-related driving reduction more often than men (14% versus 8%, p<.001). Mobility affects well-being; health professionals should consider that health conditions may cause older adults to reduce driving. Gender differences deserve attention in future research and education efforts. [ABSTRACT FROM AUTHOR]

Despite the evidence revealing benefits of chronic cardiovascular exercise on executive functions, little research has been conducted on long-term memory. We aimed to investigate the effect of physical exercise on implicit and explicit memory when attention was modulated at encoding in two groups of active and sedentary participants. With this purpose, attention was manipulated in a similar way in the implicit and explicit memory tasks by presenting picture outlines of two familiar objects, one in blue and the other in green, and participants were asked to pay attention only to one of them. Implicit memory was assessed through conceptual priming and explicit memory through a free recall task followed by recognition. The results did not reveal significant differences between groups in conceptual priming or free recall. However, in recognition, while both groups had similar discrimination for attended stimuli, active participants showed lower discrimination between unattended and new stimuli. These results suggested that exercise may have effects on specific cognitive processes, that is, that active participants may suppress non-relevant information better than sedentary participants, making the discrimination between unattended and new items more difficult. [ABSTRACT FROM PUBLISHER]

b I B I Marko Pavlovic i b SP 1 sp , University of Memphis; Kelly L. Simonton, University of Wyoming; Laura P Casey, University of Memphis i (mpvlovic@memphis.edu) 3:15 PM-4:15 PM Developing Effective Teaching in Physical Education Through Practice-Based Teacher Education The disconnect between what preservice teachers learn in teacher education programs and what they face in classrooms has been a longstanding issue (Darling-Hammond, 2021). This symposium will present the findings of four research studies that adopted PBTE in physical education teacher education programs. A Case Study Examining Washout in Professional Socialization b I B I Chris Mellor i b SP 1 sp , Adelphi University; Karen L. Gaudreault SP F sp , University of New Mexico; Kevin Richards SP F sp , University of Illinois at Urbana-Champaign; Glenn Hushman, University of New Mexico i (cmellor@adelphi.edu) B Impact of Customized Continuing Professional Development on Physical Educators' Behavioral Capability, Self-efficacy, and Outcome Expectation for Teaching Social and Emotional Competency b I B I Christine K Strater i b SP 1 sp , Metropolitan State University of Denver; Ben D. Kern, Laura C Palmer, Paul Malinowski, University of Wyoming i (ckstrater@gmail.com) B Technology Professional Development for PETE Faculty: Strengths and Gaps b I B I Jennifer M. Krause i b SP 1 sp , University of Northern Colorado; Kason O'Neil, East Tennessee State University; Taemin Ha, Brian D. Dauenhauer, Veronica Adams, University of Northern Colorado i (jennifer.krause@unco.edu) B Can Standardized Sport Skill Tests Performance Transfer to Game Performance?. [Extracted from the article]

In cycling, it is common practice to have a break in the off season longer than 4 weeks while adopting an almost sedentary lifestyle, and such a break is considered to be long-term detraining. No previous studies have assessed the effect of training cessation with highly trained young cyclists. The purpose of the present investigation was to examine effects of 5 weeks of training cessation in 10 young (20.1 ± 1.4 years) male road cyclists for body composition, haematological and physiological parameters. After training cessation, body mass of cyclists increased (P = 0.014; ES = 0.9).(L · min−1 = −8.8 ± 5.0%, mL · kg−1·min−1 = −10.8 ± 4.2%,), Wmax(W = −6.5 ± 3.1%, W · kg−1 = −8.5 ± 3.3%,), WLT1(W = −12.9 ± 7.0%, W · kg−1 = −14.8 ± 7.4%,), WLT2(W = −11.5 ± 7.0%, W · kg−1 = −13.4 ± 7.6%,) and haematological (red blood cells count, −6.6 ± 4.8%; haemoglobin, −5.4 ± 4.3% and haematocrit, −2.9 ± 3.0%) values decreased (P ≤ 0.028; ES ≥ 0.9). Five weeks of training cessation resulted in large decreases in physiological and haematological values in young top-level road cyclists suggesting the need for a shorter training stoppage. This long-term detraining is more pronounced when expressed relative to body mass emphasising the influence of such body mass on power output. A maintenance programme based on reduced training strategies should be implemented to avoid large declines in physiological values in young cyclists who aspire to become professionals. [ABSTRACT FROM PUBLISHER]

Ancient grain varieties have been shown to have some beneficial effects on health. Forty-five clinically healthy subjects were included in a randomized, double-blinded crossover trial aimed at evaluating the effect of a replacement diet with bread derived from ancient grain varieties versus modern grain variety on cardiovascular risk profile. After 8 weeks of intervention, consumption of bread obtained by the ancient varieties showed a significant amelioration of various cardiovascular parameters. Indeed, the ancient varieties were shown to result in a significant reduction of total cholesterol, low-density lipoprotein (LDL)-cholesterol and blood glucose, whereas no significant differences during the phase with the modern variety were reported. Moreover, a significant increase in circulating endothelial progenitor cells were reported after the consumption of products made from the ancient "Verna" variety. The present results suggest that a dietary consumption of bread obtained from ancient grain varieties was effective in reducing cardiovascular risk factors. [ABSTRACT FROM AUTHOR]

Purpose: This study examined the agreement between estimated peak oxygen consumption (VO2peak) obtained from the Progressive Aerobic Cardiovascular Endurance Run (PACER) fitness test and equated PACER laps derived from One-Mile Run time (MR). Methods: A sample of 680 participants (324 boys and 356 girls) in Grades 7 through 12 completed both the PACER and the MR assessments. MR time was converted to PACER laps (PACER-MEQ) using previously developed conversion algorithms. Agreement between PACER and PACER-MEQ VO2peak was examined using Pearson correlations, mean absolute percent error (MAPE), and equivalence testing procedures. Classification agreement based on health-related standards was examined using sensitivity, specificity, and Kappa statistics. Results: Overall agreement between estimated VO2peak obtained from the PACER and PACER-MEQ was high in boys, r(324) = .79, R2 = .63, and moderate in girls, r(356) = .57, R2 = .33. The MAPE for estimates obtained from PACER-MEQ was 10.3% and estimates were deemed equivalent to the PACER (43.1 ± 6.9 mL/kg/min vs. 44.6 ± 0.3 mL/kg/min). Classification agreement as illustrated by sensitivity and specificity ranged from 20.4% to 90.2% and was higher for classifications in the Healthy Fitness Zone (HFZ). Kappa statistics ranged from .14 to .51 and were also higher for the HFZ. Conclusions: Equated PACER laps can be used to obtain equivalent estimates of PACER VO2peak in groups of adolescents, but some disparities can be found when students' scores are classified into the Needs Improvement Zone. [ABSTRACT FROM AUTHOR]

Background: Regional body composition can influence disease risk and simple screening methods to identify individuals at risk are still needed. Aim: To develop equations for estimating fat and lean mass distribution, using DXA as a criterion, and to compare their performance by the association with cardiometabolic risk factors (systolic and diastolic blood pressure, high-density lipoprotein cholesterol, triacylglycerides and fasting glucose). Subject and methods: The study was conducted among 391 adults (52% female; aged 24–64 years), randomly selected from the EPIPorto cohort, with anthropometric (skin-folds and circumferences) and DXA measures. Multiple linear regression models, by sex, were used to derive predictive equations and to investigate their performance by the associations with cardiometabolic risk factors. Results: The best predicting models included circumferences and skin-folds. The final equations standard error (SEEs) ranged between 1.7–3.2% in men and 2.0–3.7% in women. Similar associations were found between regional body composition, measured by DXA or estimated by anthropometric equations, with traditional cardiometabolic risk factors, supporting the convergent validity of the equations. Additionally, it was found that central fat was associated adversely, whereas peripheral fat was favourably associated with cardiometabolic risk factors and their clustering. Conclusions: Equations combining both circumferences and skin-folds met the necessary standards for predicting regional body composition accurately, being an important tool to identify individuals with cardiometabolic risk. [ABSTRACT FROM PUBLISHER]

Objective: To evaluate the effects of an internet-platform exergame cycling programme on cardiovascular fitness of youth with cerebral palsy (CP). Methods: In this pilot prospective case series, eight youth with bilateral spastic CP, Gross Motor Functional Classification System (GMFCS) level III, completed a six-week exergame programme. Outcomes were obtained at baseline and post-intervention. The primary outcome measure was the GMFCS III-specific shuttle run test (SRT-III). Secondary outcomes included health-related quality of life (HQL) as measured by the KIDSCREEN-52 questionnaire, six-minute walk test, Wingate arm cranking test and anthropomorphic measurements. Results: There were significant improvements in the SRT-III (t = −2.5, p = 0.04, d = 0.88) post-intervention. There were no significant changes in secondary outcomes. Conclusion: An exergame cycling programme may lead to improvement in cardiovascular fitness in youth with CP. This study was limited by small sample size and lack of a comparison group. Future research is warranted. [ABSTRACT FROM AUTHOR]

Background: Seven ideal health metrics were defined by AHA to monitor cardiovascular health. This study aimed to investigate the impact of ideal cardiovascular health behaviors and factors on the development of hypertension in prehypertensive subjects.Methods: Thirty-two thousand eight-hundred and eighty-seven participants with prehypertension were included in the study after excluding for preexisting stroke, myocardial infarction or malignancy. Cox proportional hazards regression was used to calculate hazard ratios and 95% confidence intervals [CI] for the development of hypertension.Results: During a follow-up of 52.2 months, 15 500 prehypertensive participants developed hypertension. The cumulative incidence of hypertension decreased with the number of ideal health metrics increased. It was 78.61%, 71.08%, 63.15%, 56.07% and 61.62% in prehypertensive individuals carrying ≤1, 2, 3, 4 and ≥5 ideal health behaviors or factors, respectively. After adjustment for age, gender, family history of hypertension, alcohol consumption, resting heart rate, plasma triglyceride, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and high-sensitivity C-reactive protein, the risk ratios of incident hypertension in the subjects who carried 2, 3, 4, and ≥5 ideal health metrics were 0.833 (95%CI: 0.789–0.880), 0.710 (95%CI: 0.672–0.749), 0.604 (95%CI: 0.568–0.642), and 0.581 (95%CI: 0.524–0.643), respectively, in comparison to those with ≤1 ideal health metric. A similar trend was also observed in male and female populations. Poor health metrics, including body mass index, diet (salt intake), physical activity, total cholesterol, and smoking, were predictors for the development of hypertension in prehypertensive individuals.Conclusion: Ideal cardiovascular health behaviors and factors are protective factors to prevent the progression from prehypertension to hypertension. [ABSTRACT FROM PUBLISHER]

The purpose of this study was to investigate the effect of circuit exercise training and detraining, which is defined by termination of training without additional physical activities, in type 2 diabetic patients. Elderly with type 2 diabetes were divided into a group that exercised for 1 h three times a week for 12 weeks, followed by detraining for 8 weeks, or into a control group. Muscular strength, endurance, flexibility, agility, balance, body mass index (BMI), glycosylated hemoglobin (HbA1c), and blood lipid profile were measured. Of the 98 diabetic participants who joined this study, 37 patients completed the program (exercise group = 24, control group = 13). After training, muscular strength, flexibility, balance, agility, and endurance in the training group were significantly higher than at baseline and compared to the control group. HbA1c levels decreased in the training group. There was no significant improvement in BMI and blood lipid profile in either group. Flexibility and agility in the training group declined significantly after detraining. In spite of this decline, flexibility and agility were significantly higher compared to the baseline and to the control group. In type 2 diabetic patients, circuit training had a beneficial effect on the indices of physical function and glucose metabolism. Training resulted in good improvement; and during detraining, the effect of exercise training was maintained except in some parameters. [ABSTRACT FROM AUTHOR]

This study evaluates the effects of training and detraining on ankle proprioception in terms of kinesthesia in adult women. Sixty participants were randomly assigned to three groups. Tai Chi and Brisk Walking Groups went through a 16-week training period followed by an eight-week detraining period. The ankle plantar-flexion, dorsal-flexion, inversion, and eversion kinesthesia were measured every four weeks. The ankle kinesthesia in plantar/dorsal flexion of both exercise groups decreased, but the Tai Chi Group decreased more and sooner than the Brisk Walking Group. The training effects of Tai Chi exercise were retained but diminished during the detraining. The training effects of Brisk Walking exercise were not retained. The kinesthesia of ankle inversion and eversion remained unchanged after training. The results suggest that Tai Chi exercise is more effective in training ankle proprioception in plantar and dorsal flexion and in retaining the training effects compared with Brisk Walking exercise. [ABSTRACT FROM PUBLISHER]

The benefit of exercise for breast cancer-treated women is well documented. However, studies of cardiovascular fitness training for women with breast cancer-related arm lymphedema are rare. The purpose of this study was to investigate the effects of intensive pole walking on arm lymphedema in women treated for breast cancer. Thirty-five women with unilateral lymphedema were included and twenty-three completed an eight-week exercise intervention consisting of pole walking 3-5 times per week, for 30-60 min, at 70%-80% of their maximum heart rate, preceded by a two-week control period. Measurements of arm lymphedema (water displacement method), body weight, cardiovascular fitness (sub-maximal bicycle ergometer test) and subjective assessments (disability of the arm, shoulder and hand (DASH) questionnaire; heaviness and tightness using a visual analogue scale (VAS); and well-being) were performed before the control period and before and after the exercise intervention. The results indicated a significant reduction in total arm volume of the lymphedema arm ( p = 0.001), in lymphedema absolute volume ( p = 0.014) and lymphedema relative volume ( p = 0.015). Significant decreases of heart rate ( p = 0.004), DASH score ( p = 0.053) and rating of tightness in the arm ( p = 0.043) were found. Positive and negative influences on well-being were reported. The conclusion of this study is that pole walking is feasible for breast cancer-treated women with arm lymphedema. [ABSTRACT FROM AUTHOR]

Short, middle, and long-term exercise, as well as the relative intensity of the physical effort, may influence a broad array of laboratory results, and it is thereby of pivotal importance to appropriately differentiate the 'physiologic' from the 'pathological' effects of exercise. Therefore, the values of some biomarkers in physically active subjects may be cautiously interpreted since the results may fall outside the conventional reference ranges. It has been demonstrated that middle and long-term endurance and/or strenuous exercise triggers transient elevations of muscular and cardiac biomarkers. However, no data have been published about the effect of short-term maximal exercise test on the most useful muscular, hepatic and cardiovascular biomarkers. The aim of the present study was to assess the baseline concentrations of muscular, hepatic, and cardiovascular makers between trained and untrained subjects, along with changes induced by maximal exercise test. We measured C reactive protein (CRP), procalcitonin (PCT), gamma glutamyltransferase (GGT), creatine kinase-MB isoenzyme (CK-MB), Hs-TnT, NT-proBNP, CK, LDH, AST, and ALT in serum samples of physically active (trained) and physically inactive (sedentary) male collected before, immediately after a maximal exercise test and after a 30-min recovery period. Trained subjects tend to have significantly raised base concentrations of CK, CK-MB, ALT, and LDH compared to sedentary individuals, and this can be clearly interpreted as a mild injury of skeletal muscle. A single maximal exercise was also effective to transiently increase the concentrations of NT-proBNP, but not those of Hs-TnT, thus suggesting that the cardiac involvement is mostly benign in nature. [ABSTRACT FROM AUTHOR]

Background The Six-Minute Walk Test (6MWT) has been used with clinical and healthy populations to assess functional capacity and cardiovascular fitness. The aim of this study was to determine the test-retest reliability of a modified-6MWT as well as concurrent validity of walk distance with peak oxygen uptake (VO2 peak). Method Participants were 13 adults (males = 7) with intellectual disability aged 18-44 years recruited from Special Olympics, and with no medical contraindications to exercise. The 6MWT was modified to include familiarisation, a 1:1 pacer, and encouragement every 15 s. Each participant performed the graded maximal treadmill test and the modified-6MWT twice. Results Test-retest reliability of the modified-6MWT was ICC = .98, and linear regression revealed that the modified- 6MWT distance was significantly related to VO2 peak ( R = .84, p < .001). Conclusions The modified-6MWT is easy to administer and score and shows acceptable validity and excellent reliability for assessing cardiovascular fitness in adults with intellectual disability. [ABSTRACT FROM AUTHOR]

Exercise has been shown to have positive effects on the brain and cognition in healthy older adults, though no study has directly examined possible cognitive benefits of formal exercise programs in persons with mild cognitive impairment (MCI) living in structured facilities. Thirty-one participants completed neuropsychological testing and measures of cardiovascular fitness at baseline and after 6 months of a structured exercise program that included aerobic and resistance training. While exercise improved cardiovascular fitness in persons with MCI, there was no improvement in cognitive function. Rather, MCI patients in this sample declined in performance on several tests sensitive to Alzheimer's disease. Examined in the context of past work, it appears exercise may be beneficial prior to the onset of MCI, though less helpful after its onset. [ABSTRACT FROM AUTHOR]

A case of chronic back pain following multiples spine surgeries is presented as an example of postlaminectomy (failed back surgery) syndrome. The roles of physical modalities and spine rehabilitation rather than additional surgery and pharmacotherapy are described. In the commentaries the potential usefulness of adjunctive pharmacotherapy with opioids and tricyclic antidepressants is mentioned, as is the potential future need for more invasive procedures. [ABSTRACT FROM AUTHOR]

Cognitive impairment is common in persons with cardiovascular disease (CVD). Cardiac rehabilitation (CR) improves many aspects of CVD linked to cognitive impairment. The current study explored whether CR may improve cognitive function. Potential mechanisms for cognitive changes were also examined through exploratory analyses, including changes in cardiovascular fitness and cerebral blood flow. Fifty-one older adults with CVD underwent neuropsychological assessment at baseline and discharge from a 12-week CR program. Cardiovascular fitness (i.e., metabolic equivalents [METs]) was estimated from a symptom-limited volitional stress test. Transcranial doppler quantified mean cerebral blood flow velocity and pulsatility indexes for the middle cerebral artery and anterior cerebral artery (ACA). Repeated measures ANOVA showed improvements in global cognition, attention-executive-psychomotor function, and memory. Exploratory analyses revealed improvement in METs and changes in ACA flow velocity, but only improvement in METs was related to improved verbal recall. CVD patients exhibited improvements in multiple cognitive domains following a 12-week CR program, suggesting that cognitive impairment is modifiable in this population. Although other studies are needed to elucidate underlying mechanisms, exploratory analyses suggest that cognitive improvements may be better explained by physiological processes other than improved cardiovascular fitness and cerebral blood flow. [ABSTRACT FROM AUTHOR]

This pilot, multiple case study primarily examined deconditioning effects on four physical fitness components in eight participants with fibromyalgia syndrome (FMS). Fitness results after training were contrasted with fitness results immediately following two periods of inactivity. These preliminary data suggest that aspects of physical deconditioning among people with FMS may be highly individualized; therefore, making any generalizations about physical detraining in this population requires more study. Also, results regarding FMS symptoms and psychosocial factors following training versus no training on these eight participants suggest that deconditioning on these factors is very individualized. Knowledge of data-based, deconditioning information relative to FMS is important for professionals who work with older adult patients, especially activity directors who coordinate/direct recreational exercise programs or physical rehabilitation programs that involve exercise in nursing homes. Deconditioning effects from program closings, activity staff absences, or missing sessions for any reason may potentially affect fitness, FMS symptoms, psychosocial function, and possibly activities of daily living (ADL). This potential negative effect on ADL can increase workload and place much more stress on the nursing staff. All of this requires more research for a more thorough understanding. [ABSTRACT FROM AUTHOR]

Background. Polycystic ovary syndrome (PCOS) is independently associated with the major cardiovascular risk factors. The aim of this study was to examine the echocardiographic profiles of patients with PCOS using conventional echocardiographic methods and tissue Doppler imaging. Methods. For this study, we have registered 48 women with PCOS and 21 healthy control subjects who were mathced with respect to age and body mass index. Standard two-dimensional and M-mode measurement, transmitral valve flows and tissue Doppler imaging of mitral and tricuspid anulus were recorded. Results. In PCOS and control groups, left ventricular and atrium diameters, ejection fraction, mitral E/A ratio, deceleration time and isovolumic relaxation time were similar. There were no significant differences between patients with PCOS and control subjects with respect to tissue Doppler profiles. Conclusion. Patients with PCOS execute echocardiographic measures of cardiac function that are similar to those of healthy women. [ABSTRACT FROM AUTHOR]

This study examined the associations between indicators of health-related physical fitness (cardiovascular fitness and body mass index) and academic performance (Texas Assessment of Knowledge and Skills). Partial correlations were generally stronger for cardiovascular fitness than body mass index and consistently stronger in the middle school grades. Mixed-model regression analyses revealed modest associations between fitness and academic achievement after controlling for potentially confounding variables. The effects of fitness on academic achievement were positive but small. A separate logistic regression analysis indicated that higher fitness rates increased the odds of schools achieving exemplary/recognized school status within the state. School fitness attainment is an indicator of higher performing schools. Direction of causality cannot be inferred due to the cross-sectional nature of the data. [ABSTRACT FROM AUTHOR]