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Detecting the anchoring length is an integral part of the quality inspection of the bolt anchoring, which is crucial to the safety of the roadway support. This paper studies the influence of the anchoring length on the propagation characteristics of the exciting stress wave of the bolt. The research finds that the change in the anchoring length affects the attenuation rate and frequency distribution of the stress wave signal amplitude. Under the same test conditions, the anchoring length negatively correlates with the consolidation wave velocity. The VMD analysis and processing method decomposes the original detection signal once or the characteristic mode function twice. The bottom reflection time is obtained from the bottom reflection signal identified according to the decomposed mode function. Based on the propagation characteristics of the exciting stress wave in the anchor rod, a method of calculating the anchoring length using the bottom reflection time is proposed. Experimental verification of anchoring models for different anchoring lengths is carried out. The calculated results are consistent with the actual anchoring length; the longer the length, the smaller the relative error. The error rate meets the accuracy requirements of on-site engineering tests and guarantees safe production. [ABSTRACT FROM AUTHOR]

Three mega-clusters dominate the cybersecurity industry: the San Francisco Bay Area, the Washington D.C. area and Israel. Together they are home to about half the influential cybersecurity firms; they have remained dominant since industry take-off in the 1990s. How have they remained dominant? We answer this question by synthesizing firm-level data, case studies, and interviews, compiling an extensive history of their evolution; then using a Geographic Information System to map these clusters. Applying the Menzel and Fornahl cluster lifecycle model, we find these clusters advanced into the Growth (2nd) stage but have not reached an equilibrium state. The model points to heterogeneity as key to avoiding cluster weakening through lock-in. Three vectors of heterogeneity explain how these clusters remain dominant: The absence of a de facto standard design, spatial expansion, and the ever-increasing cyber-threat landscape. Additionally, powerful anchor institutions are present in two of the three clusters. [ABSTRACT FROM AUTHOR]

[...] Leaving that house was really emotional ... because it's the ... that's the thing it's the boys' childhood and Grace's childhood all wrapped up in that house. Keywords: Material culture; mobility; anchor; home; moving house; storage; Cultura material; movilidad; ancla; hogar; mudanza; almacenamiento; Culture matérielle; mobilité; attache; foyer; déménagement; entreposage EN Material culture mobility anchor home moving house storage ES Cultura material movilidad ancla hogar mudanza almacenamiento FR Culture matérielle mobilité attache foyer déménagement entreposage 990 1006 17 09/09/22 20220901 NES 220901 Introduction Moving home is a significant moment experienced by most over the course of their life, and the practices of sorting through and packing household possessions in order to move and remake home are central to the experience. Gill's experience of moving house involved the stress of renovating their new house and was inflected by her changing family dynamics as her children grew up and the "family home" changed its meaning. Mobility, anchor, home, moving house, Material culture, storage. [Extracted from the article]

Viruses have multiple mutation rates that are higher than any other member of the kingdom of life. This gives them the ability to evolve, even within the course of a single infection, and to evade multiple host defenses, thereby impacting pathogenesis. Additionally, there are also interplays between mutation and recombination and the high multiplicity of infection (MOI) that enhance viral adaptability and increase levels of recombination leading to complex and conflicting effects on genome selection, and the net results is difficult to predict. Recently, the outbreak of COVID-19 virus represents a pandemic threat that has been declared a public health emergency of international concern. Up to present, however, due to the high mutation rate of COVID-19 virus, there are no effective procedures to contain the spread of this virus across the globe. For such a purpose, there is then an urgent need to explore new approaches. As an opinion, the present approach emphasizes on (a) the use of a nonspecific way of blocking the entry of COVID-19 virus as well as its variants into the cells via a therapeutic biocompatible compound (ideally, "in a pill") targeting its spike (S) glycoprotein; and (b) the construction of expression vectors via the glycosyl-phosphatidylinositol, GPI, anchor for studying intermolecular interactions between the spike S of COVID-19 virus as well as its variants and the angiotensin-converting enzyme 2 (ACE2) of its host receptor for checking the efficacy of any therapeutic biocompatible compound of the nonspecific way of blocking. Such antiviral drug would be safer than the ACE1 and ACE2 inhibitors/angiotensin receptor blockers, and recombinant human ACE2 as well as nucleoside analogs or protease inhibitors used for fighting the spread of the virus inside the cells, and it would also be used as a universal one for any eventual future pandemic related to viruses, especially the RNA viruses with high mutation rates. [ABSTRACT FROM AUTHOR]

Steel plate-concrete joints are often applied in strengthening of engineering structures. Eighteen steel plate-concrete joints (connection length of 260–520 mm, width of 80 mm) were tested, which were classified into three types: (a) anchor-connected specimens (BC specimens), in which the steel plates and concrete were connected with anchors; (b) adhesive-connected specimens (AC specimens), in which the steel plates and concrete were connected with adhesive; (c) anchor- and adhesive-connected specimens (BAC specimens), in which the steel plates and concrete were connected with both anchors and adhesive. The following conclusions were drawn. (1) For the same connection length, the ultimate loads of the BAC specimens (e.g. 127 kN) were approximately 78% of the sum of those BC and AC specimens (e.g. 112 and 53 kN). (2) For the BAC specimens, almost all of the load was borne by the adhesive and the anchor hardly shared any load before the specimens reached the peak load. (3) A modified semi-theoretical and semi-empirical formula (C-T model) has been used, which was used to predict the ultimate load of the BAC and AC specimen with satisfactory precision. [ABSTRACT FROM AUTHOR]

Hydraulic fracturing is a widely used method in the mining industry. In the case of underground workings, the formation of parallel fractures across the borehole axis is of great particular interest for many geotechnical issues, for example, improving the production of coal seam gas or making an impermeable screen in massif to eliminate a water inflow. The article presents a hydofrac tool's scheme with one inflatable packer promoting the creation of transverse crack. We observe in the laboratory the behaviour of the packer to estimate the displacement of its sliding end when the pressure was applied. These data were used to assess the possibility to form a fracture in the desired direction. In addition, numerical studies of the stress state caused by loading, created with the help of the downhole tool, have been carried out. Analysis of parameters necessary for the formation of an initial crack on the borehole wall is presented. Results show that the using of the borehole tool equipped with an anchoring module allows to create conditions for the appearance of a transverse initiating crack. It has been established that a decrease in the length of the anchor leads to an increase in the tensile axial stresses. [ABSTRACT FROM AUTHOR]

Light-induced dimerizing systems, e.g. iLID, are an increasingly utilized optogenetics tool to perturb cellular signaling. The major benefit of this technique is that it allows external spatiotemporal control over protein localization with sub-cellular specificity. However, when it comes to local recruitment of signaling components to the plasmamembrane, this precision in localization is easily lost due to rapid diffusion of the membrane anchor. In this study, we explore different approaches of countering the diffusion of peripheral membrane anchors, to the point where we detect immobilized fractions with iFRAP on a timescale of several minutes. One method involves simultaneous binding of the membrane anchor to a secondary structure, the microtubules. The other strategy utilizes clustering of the anchor into large immobile structures, which can also be interlinked by employing tandem recruitable domains. For both approaches, the anchors are peripheral membrane constructs, which also makes them suitable for in vitro use. Upon combining these slower diffusing anchors with recruitable guanine exchange factors (GEFs), we show that we can elicit much more localized morphological responses from Rac1 and Cdc42 as compared to a regular CAAX-box based membrane anchor in living cells. Thanks to these new slow diffusing anchors, more precisely defined membrane recruitment experiments are now possible. [ABSTRACT FROM AUTHOR]

Soil reinforcement employing geosynthetics is significantly influenced by interactions which are governed by friction and adhesion at interface. To enhance interactions at soil–geogrid interface under direct shear conditions, effects of attaching elements as anchors to reinforcement has been evaluated. A well and poorly graded sand, one geogrid type, anchors with three different size and clamping lengths of 2, 4 and 6 cm from shear surface were used. Samples were prepared with a relative density of 80% and tested dry under normal pressures of 12.5, 25 and 50 kPa using large direct shear test. Factors investigated included soil grading and particle size, anchor size and anchorage length together with normal pressures. Results shows by attachment of anchors to upper geogrid surface, shear resistance to failure is significantly enhanced with increase in normal pressure and anchor size. This is attributed to soil-anchor friction at interfaces, mobilisation of soil passive resistance in front of anchors and tensile strength of reinforcement. Non-uniform sand having larger and angular particles resulted in more effective interactions with geogrid and anchors at interfaces and resulted in greater resistance to shear failure under direct shear loading. Soil particle size and anchorage length were found to be less influential factors on soil–geogrid interactions. [ABSTRACT FROM AUTHOR]

This article examines the branding and marketing strategies of New Zealand Producers Boards which were established in the early 1920s to coordinate the export of butter and lamb to Britain. The brand 'New Zealand' featured prominently in the promotion of lamb exports to Britain, whereas much more emphasis was placed on the 'Anchor' brand for butter. Because the 'Mother Country' was by far the biggest single export market for New Zealand butter and lamb, the branding and marketing activities of the Boards emphasised the strong cultural affinity that existed between Britain and New Zealand. Drawing on the relevant branding and marketing literature, the Boards' annual reports, and reports by the Ministry of Agriculture and Fisheries, we show that 'New Zealand' and 'Anchor' conveyed the fundamental message of a shared British identity. [ABSTRACT FROM AUTHOR]

In team sports, peripheral vision might be useful to simultaneously monitor movements of opponents and teammates. Until now, however, little is known about the perceptual-cognitive processes underlying peripheral vision in a sporting task. Therefore, we used a mixed-methods approach with in-situ decision making (3 vs. 3 situations) and retrospective verbal reports to identify perceptual strategies used for optimal information pick-up in high- and low-skilled football players. Our results show that the use of peripheral vision by central defenders depends on the position of the ball and the position of the direct opponent. Players were shown to either use a pivot strategy, whereby they frequently look at the direct opponent if he is not in the possession of the ball in addition to making saccades to monitor other players, or they employ a more direct strategy, in which gaze is anchored on this location, avoiding saccades and monitoring the other players with peripheral vision. Based on our findings we make recommendations about how these gaze strategies can be further tested in future research and how sports practice can benefit from these results. [ABSTRACT FROM AUTHOR]

To reveal the dynamic behavior of soil anchorage landslide and the mechanical feature of anchors at different frequencies, a shaking table test was performed on a 1:7 scale soil anchorage landslide. Actual seismic wave measured from the Wenchuan earthquake, sinusoidal waves with different frequencies were applied to the model. The acceleration response of the anchorage landslide in frequency domain was analyzed, and the strain distribution of anchors at 1.15 Hz sinusoidal wave and 3.45 Hz sinusoidal wave were investigated separately. The testing results indicate that the anchorage landslide is sensitive not only to higher frequencies (near the natural frequency of the landslide) at low loading amplitude but also to ultra-low frequencies at high loading amplitude. At ultra-low frequency 1.15 Hz sinusoidal wave, when the loading amplitude is low and medium (0.05-0.6 g), the bottom anchor bears greater force. But when the loading amplitude is high (0.8 g), the top anchor bears most of the anchorage force. At 3.45 Hz sinusoidal wave that near the natural frequency of the landslide, no matter how the loading amplitude, the top anchor plays significant role, especially at higher loading amplitude (0.3-0.6 g). [ABSTRACT FROM AUTHOR]

The design of anchored wall systems is governed by the bond strength between the grout and the surrounding soil/rock in the grouted zone. Published work on the reliability of anchored retaining systems focuses on ultimate limit state considerations to ensure a target level of reliability against pullout of the anchor in the bonded zone. These studies do not shed light on the uncertainty in the bond stress – displacement relationship of the grout/soil interface. This uncertainty exists as a result of spatial variability in the soil/rock properties even within the same geologic unit. The primary objective of this paper is to quantify the uncertainty in the bond stress – displacement relationship to aid the serviceability limit state design of anchored wall systems. To achieve this objective, a database of shoring anchor tests from real projects that were executed in several sites around Beirut is assembled and analysed. The tests are categorised based on three different geologic units (Limestone, Marls, and Clays) that are common to many geologic settings in the world. The bond stress – displacement relationship is modelled with a hyperbolic model and the statistics of the model are derived from the assembled database and classified based on the geologic units analysed. [ABSTRACT FROM AUTHOR]

An experimental study was completed on the behavior on post-installed bonded anchors in ultra-high performance fiber reinforced concrete with a compressive strength higher than 150 MPa. The aim was to analyze the failure mechanisms in static pullout tests. The diameter of the tested anchors was 12 mm and the studied parameters were the embedment depth, the edge distance and the state of cracking of the concrete block. In case of tests without edge effect in uncracked concrete, a combined pullout and concrete cone failure occurred for an embedment depth lower than 60 mm. The recorded mean bond stress was 32.5 MPa for uncracked concrete and 16.3 MPa for cracked concrete with a crack width of approximately 1 mm. A splitting failure was observed for shallow embedment and for edge distances lower than 60 mm. For this tested special anchor system, the increase in tensile strength provided by the metallic fibers enhances the tensile behavior of anchors in comparison to normal strength concrete. It is necessary to adapt the design codes developed for normal strength concrete in order to have more accurate and reliable prediction methods. [ABSTRACT FROM AUTHOR]

Aims: To explore the validity of change scores of the Children's Handuse Experience Questionnaire (CHEQ). Methods: Analysis of the CHEQ included 44 children (15 girls) between 6-16 years (median 9.0; IQR 8-11) with unilateral cerebral palsy, with baseline and post- (two-week intensive) intervention assessments using the Goal Attainment Scale (GAS) as external anchor for change. Hypotheses on the magnitude of expected changewere formulated and correlation coefficients and effect sizes calculated. Receiver operating curve analysis was performed and the area under the curve (AUC) calculated to investigate the ability of CHEQ to discriminate between improvement and non-improvement according to GAS. Results: All hypotheses about the magnitude of change were confirmed supporting longitudinal validity of CHEQ scales to measure change in the perception of bimanual performance. AUCs for the Grasp efficacy and the Time utilization were slightly below, and for the Feeling bothered slightly above the threshold. The latter one accurately discriminating between children that improved and did not improve according to the GAS. Conclusions: Evidence was found that CHEQ scales capture change in bimanual performance but with limited accuracy for two out of three scales. The validity of CHEQ change scores needs to be further explored in a wider population. [ABSTRACT FROM AUTHOR]

An anchored soldier pile wall is used for deep excavation stabilisation in the vicinity of buildings which are sensitive to displacement. In the current study, a three-dimensional model of anchored soldier pile wall was created in Abaqus software to estimate displacement and internal forces, especially due to surcharge. The effects of soil type, wall height, spacing of anchors and soldier pile rigidity were analysed. The results indicate that the surcharge had great effect on the wall deformation and the bending moment of the soldier piles; however, the bending moment of the lagging was less influenced by the surcharge. [ABSTRACT FROM AUTHOR]

Television anchors are key public figures in the American news media, vital for the ratings success of their outlets. This study uses content analysis and framing theory to examine US network news anchors' role at a pivotal career moment—the last minutes in the all-powerful anchor chair—their swan songs. These final words are examined for messages as anchors express gratitude, sum up careers, provide journalism insights, and pronounce final words of wisdom. The textual analysis revealed several dominant frames—becoming one with the audience, expressions of gratitude to staff and viewers, the anchors' perception of their historical role noting predecessors and successors, and insightful wisdom about journalism's role in society. The visual analysis showed a style reinforcing a professional presence, signaling authority, and objectivity. Each American lodestar anchor was different, yet they were similar in how they said goodbye and how they wanted to be remembered. [ABSTRACT FROM AUTHOR]

Although the uplift behavior of offshore plate anchors under undrained conditions has been investigated well in the past, studies on the behavior of anchors under long-term sustained loading are in relatively few numbers. The time required for consolidation under sustained load is important because the shear strength of soil changes after dissipation of excess pore pressure. In this paper, small strain finite-element analyses have been performed to investigate the consolidation time history above and beneath strip anchors. The modified cam clay plasticity constitutive model is used for modeling coupled pore fluid stress analysis. The effects of magnitude of preloading with embedment level have been studied. As expected, the FE results have shown that excess pore pressure dissipation time for soil above the anchor increased with the increase in embedment depth and the magnitude of preload. Rapid dissipation of negative excess pore pressure beneath the anchor was observed with increasing embedment depth, if the preload magnitude is equal to or more than 60% of the undrained capacity. Observed consolidation responses are presented as nondimensional design charts and simplified equations for ease of practice. [ABSTRACT FROM AUTHOR]

Since 1994 almost 2000 ancient rupestral engravings, both verbal and pictorial, have been discovered in southern Attica. These include about 200 depictions of warships, merchantmen, and smaller vessels of various types. These engravings are dated to the 6th century BC on the basis of their style and the formal characteristics of their associated inscriptions. They contain the earliest-known labelled images of the Greek ship types triakonter, pentekonter, and holkas, as well as the earliest depictions of two-masted merchantmen, and possibly Greek triremes. They also include the earliest images of the three-pronged ram and of the spur of a merchantman used as a cutwater, as well as possibly the earliest depictions of lead sheathing and of the spritsail. [ABSTRACT FROM AUTHOR]

Excavation inPosidonia oceanicamatte in the ancient harbor of Klazomenai/Liman Tepe, on the Aegean coast of Turkey, demonstrates the stratigraphic archaeological potential of underwater excavation. Among the finds is a fractured wooden anchor arm exposed in situ. The anchor arm dates to approximately 600b.c.based on stratigraphically associated ceramics, a dating supported by radiocarbon. The arm was found embedded in this marine sediment, which preserved the arm in its set position within the ancient sea floor. This archaeological excavation through matte and silt harbor sediments overturns the misconception that stratigraphic excavation is impossible in a marine environment. The excavation further boosts optimism regarding the preservation of maritime heritage along the littoral of the eastern Aegean and the many other Mediterranean regions wherePosidonia oceanicagrows. [ABSTRACT FROM PUBLISHER]

Thermal anchor, one of the key components to keep temperature balance of gravity magnet support, should be avoided welding defects in its welding joints, which endure large forces when the international thermonuclear experimental reactor (ITER) fusion device is operating. The influences of brazing fillers and brazing methods on the cracks in joints of thermal anchor were investigated by microstructure analysis. The results have shown that the copper penetrating cracks were observed in the heat-affected zone (HAZ) of tungsten inert gas (TIG) arc brazing joints welded by CuSi3, CuSi3Mn, and Ag45CuSnNi brazing fillers, which are chiefly responsible for the diffusion and penetration of copper, derived from molten brazing filler metal into the 316L/316LN austenitic grain boundaries leading to embrittlement. The intimate contact between liquid copper and austenitic steel surface and the surface stress concentration of the austenitic steel are the main formative factors for the copper penetrating cracks. Adopting brazing fillers without containing copper or employing vacuum brazing can effectively avoid the copper penetrating cracks in the joints of ITER thermal anchor. [ABSTRACT FROM AUTHOR]

Surveys carried out in 2009, during a project for the creation of three underwater archaeological parks in Libya, have allowed archaeologists both to analyse already known ancient structures and to discover new evidence about the harbour areas of the ancient cities of Tolmetha and Leptis Magna. [ABSTRACT FROM AUTHOR]

Ranibizumab, a recombinant, humanized, monoclonal antibody antigen-binding fragment that neutralizes all VEGF-A isoforms, is the first US FDA-approved therapy for neovascular age-related macular degeneration (AMD) to result in improvement in visual acuity. The benefit of intravitreal ranibizumab applies to all angiographic subtypes of neovascular AMD and across all lesion sizes. The two original phase III studies (ANCHOR and MARINA) demonstrated sustained visual acuity (VA) gains over a two-year monthly dosing schedule. Following these trials, several studies looked at ways to decrease the treatment burden while maintaining similar visual gains. These trials included PIER, PrONTO, EXCITE, SUSTAIN, HORIZON, and CATT. Visual acuity data shows that monthly dosing of ranibizumab produces superior vision outcomes compared to a less-frequent, fixed-dosing schedule. Intravitreal ranibizumab is well tolerated and shown to have a very low rate of adverse ocular or systemic side-effects. [ABSTRACT FROM AUTHOR]

The seismic behaviour of anchored sheet pile walls is a complex soil-structure interaction problem. Damaged sheet pile walls are very expensive to repair and their seismic behaviour needs to be investigated in order to understand their possible mechanisms of failure. The research described in this paper involves both centrifuge testing and Finite Element (FE) analyses aimed at investigating the seismic behaviour of an anchored sheet pile wall in dry sand. The model wall is tied to the backfill with two tie rods connected to an anchor beam. The accelerations of the sheet pile wall, the anchor beam and the soil around the wall were measured using miniature piezoelectric accelerometers. The displacement at the tip of the wall was also measured. Stain gauges at five different locations on the wall were used to measure the bending moments induced in the the wall. The anchor forces in the tie rods were also measured using load cells. The results from the centrifuge tests were compared with 2-D, plane strain FE analyses conducted using DIANA-SWANDYNE II and the observed seismic behaviour was explained in the light of these findings. [ABSTRACT FROM PUBLISHER]

During a month-long survey of the coastline along the south-eastern Bozburun peninsula, Turkey, nine shipwreck sites were discovered. Of these, five have historical significance and represent a chronological range from the Roman Imperial to Renaissance periods. This article provides a description of the sites and associated artefacts, and attempts a provisional analysis for each wreck's operational date as well as the nature of the finds in their historical context. © 2006 The Author [ABSTRACT FROM AUTHOR]

Management of complete external third nerve palsy is a challenge to a strabismologist; as four of six extra-ocular muscles are affected, it leaves eye in fixed hypotropic and exotropic position (Srivastava et al., 2004). Although numerous surgical procedures have been described, none has been found to be ideal for all cases. Horizontal supramaximal recession-resection procedure may work in cases having some function of medial rectus (Harley, 1980). In cases of complete external palsy, anchoring of globe to periosteum of medial orbital wall using different structures has been described (Villasenor Solares et al., 2000; Bicas, 1991; Salazar-Leon et al., 1998), as recession-resection may result in large residual deviation and/or eye drifts back to abducted position due to unopposed lateral rectus action (Von Noorder, 1996). These anchoring procedures are with associated problems of skin incision, thigh surgery or loss of superior oblique function (Villasenor Solares et al., 2000; Bicas, 1991; Salazar-Leon et al., 1998). We describe a new and safe technique for management of complete external third nerve palsy by anchoring insertion of medial rectus to medial wall periosteum, posterior to posterior lacrimal crest, along with supra maximal recession of lateral rectus. [ABSTRACT FROM AUTHOR]