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Your search keyword '"Cruijsen, M."' showing total 1 results
Start Over Author "Cruijsen, M." Publisher taylor & francis ltd
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1. Use of azacitidine and its safety and efficacy in daily clinical practice in The Netherlands: the OCEAN study.

Author

Cruijsen, M., van der Velden, W.J.F.M, de Haan, A.F.J., Klein, S. K., Hoogendoorn, M., Tromp, Y., de Valk, B., van Rees, B., de Boer, F., van der Spek, E., Pruijt, J., Verdonck, L.F., Vellenga, E., Blijlevens, N., van de Loosdrecht, A. A., and Huls, G.

Subjects
*PATIENT compliance, *BLOOD transfusion reaction
Abstract

Several clinical studies have shown superiority of azacitidine compared to conventional care regimens in frail patients with MDS and AML [[1]]. In 57 (65%) of 87 patients without HI, and in 51 (81%) of the 63 patients that stopped treatment within 6 cycles, no BME was performed. In 13 out of 22 patients, the dose reduction was done before HI was reached, in 3 of them a BME was done before dose reduction (1 patient had CRi, and 2 patients had SD). Thirteen (6%) patients stopped treatment after the 1st cycle of azacitidine and 63 (37%) patients stopped within 6 cycles. [Extracted from the article]

Published
2020
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