1. Feasibility and clinical impact of a portable bi-level ventilation device in patients with severe chronic obstructive pulmonary disease and exertional dyspnea: preliminary results from a clinical series.
- Author
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De Giacomi, Federica, Bonaiti, Giulia, Montanelli, Filippo, Della Zoppa, Matteo, Messinesi, Grazia, Carlucci, Annalisa, Luppi, Fabrizio, Pesci, Alberto, and Faverio, Paola
- Subjects
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MEDICAL rehabilitation , *MECHANICAL ventilators , *LUNG diseases , *FUNCTIONAL status , *MANN Whitney U Test , *FISHER exact test , *DYSPNEA , *ARTIFICIAL respiration , *OBSTRUCTIVE lung diseases , *MENTAL depression , *DESCRIPTIVE statistics , *QUESTIONNAIRES , *CHI-squared test , *CASE studies , *ANXIETY , *DATA analysis software , *MEDICAL equipment - Abstract
We explore home use of a portable bi-level ventilation device among patients with severe chronic obstructive pulmonary disease (COPD), and describe changes in the patients' physical activity levels, perceived dyspnea, anxiety and depression, as well as their satisfaction with the device, after one month of use. Methods. Forty patients with severe COPD and exertional dyspnea were instructed to use VitaBreath® device (Philips, Respironics) during efforts or activities of daily living for 4 weeks, and agreed to answer questionnaires on anxiety, depression, dyspnea and physical activity. Results. Twenty-six (65%) patients used the VitaBreath® device for four weeks, while 14 patients (35%) stopped early for various reasons. Among patients who completed the 4-week course, no differences in dyspnea and physical activity were observed between baseline and follow-up (p-values 0.41 and 0.19, respectively). Thirteen (50%) and 15 (57%) patients experienced reduced anxiety and depression, respectively. Patients with greater functional impairment and less autonomy in activities of daily living tended to view the device more positively. Conclusion. Home use of portable bi-level positive-pressure ventilation devices by patients with COPD may alleviate disease-related anxiety and depression, particularly in more severe cases of COPD. Future portable device design should feature adjustable inspiratory/expiratory pressures. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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