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Your search keyword '"Hinckley, S."' showing total 2 results
Start Over Author "Hinckley, S." Publisher taylor & francis ltd
2 results on '"Hinckley, S."'

1. Theme 09 - Clinical Trials and Trial Design.

Author

Katz, J., Vu, T., Chiò, A., McDermott, C., Devos, D., Gordon, G., Johnston, M., Maier, J., Trimmer, J., Tansy, A., Shefner, J., Angela Genge, A., Boggs, B., Ganti, R., Hinckley, S., Johnson, K., Kaneb, H., Polzer, J., Rubino, S., and Salmon, K.

Subjects
EXPERIMENTAL design, AMYOTROPHIC lateral sclerosis, LIBRARY users, RESEARCH personnel, LIBRARY resources
Abstract

The text is a report on clinical trials and trial design in the field of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Degeneration (FTD). It is authored by a large number of researchers and experts in the field. The report provides a comprehensive overview of ongoing clinical trials, trial design considerations, and potential future directions for research in ALS and FTD. It is a valuable resource for library patrons conducting research on these specific topics. [Extracted from the article]

Published
2023
Full Text
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2. Theme 05 - HUMAN CELL BIOLOGY AND PATHOLOGY (including iPSC studies).

Author

Hallegger, M., Lee, F., Chakrabarti, A., Kuret, K., Luscombe, N., Ule, J., Salcher-Konrad, M., Mizielinska, S., Denton, K., Knight, H., Guzzetti, A., Chen, N., Lukashev, M., Gray, T., Kamelgarn, M., Bussgang, J., Hamwi, Y., Hinckley, S., Elbaum, D., and Marques, C.

Subjects
HUMAN biology, CYTOLOGY, FRONTOTEMPORAL lobar degeneration, AMYOTROPHIC lateral sclerosis
Abstract

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. TDP-43 triggers mitochondrial DNA release via mPTP to activate cGAS/STING in ALS. TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis. [Extracted from the article]

Published
2021
Full Text
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