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The Friedel–Crafts acylation of ferrocene catalyzed by a new type of catalyst of rare-earth solid superacid sulfated zirconia SZR3+ was developed. Comparison of catalytic activities between different solid acid catalysts is presented. The catalyst, sulfated zirconia ytterbium SZNYb3+, showed interesting catalytic properties for preparation of acylferrocenes. Furthermore, the catalyst could be regenerated and reused in succession after simple filtration. [ABSTRACT FROM AUTHOR]

The prevalence of eosinophilic CRSwNP in China has increased significantly over the last 20 years, noninvasive methods that could assist in diagnosis are urgently needed. The aim of this study is to explore the clinical significance of peripheral blood eosinophil in diagnosing ECRS. We conducted a prospective study of 221 patients diagnosed with CRS. Lund–Mackay score, peripheral blood eosinophil absolute count, peripheral blood eosinophil percentage were detection to compare the clinical features with ECRS and non-ECRS. ROC curve was performed to assess the efficiency of clinical index to predict ECRS. The ECRS group of patients had significantly higher scores compared with those of the non-ECRS group. Different extent and severity of mucosal thickening on total Lund–Mackay scores, anterior ethmoidal, posterior ethmoidal and ostiomeatal complex have confirmed different blood eosinophil levels in CRS patients. The combination of peripheral blood eosinophil percentage and posterior ethmoidal score to predict ECRS was 0.807. The increase in peripheral blood eosinophil percent indicates the deterioration the inflammation of chronic rhinosinusitis and the level of posterior ethmoidal score and peripheral blood eosinophil percentage have a positive predictive value regarding ECRS identification. [ABSTRACT FROM AUTHOR]

Conclusion: Gene transcription and protein expression of α-ENaC showed a divergent expression in association with the development of OME induced by barotrauma. Objectives: ENaC was identified to mediate the fluid absorption through epithelia of the middle ear. This study was designed to investigate the involvement of ENaC in otitis media with effusion (OME) induced by barotrauma. Methods: A rat model of otitis media with effusion was established using a pressure cabin. The dynamic expression of α-ENaC was detected by Real time-PCR and western blot in the course of otitis media. Results: Compared with the control, the volume of α-ENaC mRNA and protein increased significantly by 3.18-fold and 2.8-fold on the 3rd day, respectively, while decreased by 0.54-fold and 0.32-fold on the 7th day, respectively. [ABSTRACT FROM AUTHOR]

Conclusion: Gene transcription and protein expression of α-ENaC showed a divergent expression in association with the development of OME induced by barotrauma. Objectives: ENaC was identified to mediate the fluid absorption through epithelia of the middle ear. This study was designed to investigate the involvement of ENaC in otitis media with effusion (OME) induced by barotrauma. Methods: A rat model of otitis media with effusion was established using a pressure cabin. The dynamic expression of α-ENaC was detected by Real time-PCR and western blot in the course of otitis media. Results: Compared with the control, the volume of α-ENaC mRNA and protein increased significantly by 3.18-fold and 2.8-fold on the 3rd day, respectively, while decreased by 0.54-fold and 0.32-fold on the 7th day, respectively. [ABSTRACT FROM AUTHOR]