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AbstractThis study determined prevalence and late-infancy predictors of persistent externalizing problems during early-childhood for screening in clinical practice. 1353 primary-caregivers with 8-month infants were recruited systematically from universal well-child centers and followed to 4–5 years (‘Families in Mind’ population-based randomized trial). Externalizing problems were measured by Child Behavior Checklist at 2, 3 and 4–5 years; child/family predictors at 8–12 months. Four percent of toddlers developed persistent externalizing problems of clinical concern (≥2 time-points). Key late-infancy predictors were primary-caregiver distress, harsh discipline and low nurturing. Findings suggest benefits of screening these family factors in late-infancy via universal services to identify early-starters’. [ABSTRACT FROM AUTHOR]

Interventions implemented in the digital space play an important role in the response to global concerns about the prevalence of online child sexual abuse. Digital detection software (e.g. Sweetie) utilized to combat this behavior is a well-known example. Far fewer examples of digital interventions focused on its prevention exist. This review sought to identify digital interventions currently being implemented that aim to prevent online child sexual abuse, or intervene early, through deterrence and redirection. Guided by the PRISMA scoping review framework, a search was conducted across four databases, with snowballing from reference lists of selected sources. After exclusion criteria were applied, six sources were selected for review. Findings suggest that digital interventions (e.g. warning messages and chatbots) can be used to deter and redirect individuals at-risk of, or in the early stages of engaging in online child sexual abuse, with greater deterrent effects observed when messaging aligns with situational crime prevention principles. However, limited application and evaluation of these interventions to date constrains inferences regarding the impact of these prevention efforts. To supplement findings, several other emerging examples of digital interventions and conceptual/theoretical works (that did not meet the original inclusion criteria) are cited. Findings of this review should be considered alongside these other examples to inform the ongoing design and scaling up of digital interventions aimed at preventing online child sexual abuse. [ABSTRACT FROM AUTHOR]

AbstractClinical implicationsFor athletes, the use of a mouthguard is fundamental. This device allows for the absorption and dissipation of energy from the impact. These rehabilitated patients will be subjected to oral-facial injuries and trauma again once they return to contact sports. Evaluate the mechanical effect of an impact over a maxilla region where implant-abutment-crown are present, and this mechanical behavior will be analyzed through the evaluation of maximum stress distributions. A three-dimensional geometry of an implant system (implant-abutment-crown and the bone) was obtained from computed tomography and transformed into separate meshes. A mouthguard was created to cover the surface, and a steel ball with a velocity of 1 m/s was used as the impact object. The results were divided into the individual analysis of the stress generated on each variable studied. The mouthguard was capable of reducing the stress on the implant by 71.81%, stress on the abutment by 73.20%, on both pieces by 74.30%, as well as reducing the impact on the prosthetic crown by 98.32%, thus preventing its fracture. A mouthguard is capable of reducing stress on the implant-abutment-crown complex and bone cortex.The present data contribute to the specialties of Sports Dentistry and Implantology, offering scientific evidence of the importance of a mouthguard to provide the best protection for athletes rehabilitated with dental implants. [ABSTRACT FROM AUTHOR]

Adverse childhood experiences (ACEs) have gained prominence in recent literature for their effects on the well-being of children. Children with ACEs often exhibit maladaptive behaviors, such as anxiety, depression, maladaptive relationships, drug usage, and school issues. Adventure therapy (AT) improves youth’s ability to form relationships, develop self-confidence, improve decision-making, and utilize effective coping strategies. This paper explores the use of AT as a primary, secondary, and tertiary intervention strategy to offset and/or prevent deleterious effects experienced by adolescents with ACEs and provides a case example to conceptualize the use of AT as an intervention for adolescents with ACEs. Considerations, limitations, and resources for conducting AT with lower-SES youths are discussed. [ABSTRACT FROM AUTHOR]

In the last 30 years, universities and colleges have been strongly encouraged to consider the impact these systems have on health promoting behaviors for students, staff, faculty, and surrounding communities. Higher Education Institutions are prime settings to promote prevention and outreach efforts for positive mental health. University and College Counseling Centers have historically been leaders in outreach and prevention delivery thus the need for competencies is evident. Utilizing a trauma-inclusive and social justice lens, this article will focus on outlining six outreach competencies: (1) integrate, (2) scope, (3) collaborate, (4) assess, (5) implement, and (6) evaluate. The authors provide application examples for further illustration. [ABSTRACT FROM AUTHOR]

Objective: With our aging population, an increasing number of older adults with hearing loss have cognitive decline. Hearing care practitioners have an important role in supporting healthy aging and should be knowledgeable about cognitive decline and associated management strategies to maximize successful hearing intervention. Methods: A review of current research and expert opinion. Results: This article outlines the association between hearing loss and cognitive decline/dementia, hypothesized mechanisms underlying this, and considers current research into the effects of hearing intervention on cognitive decline. Cognition into old age, cognitive impairment, dementia, and how to recognize cognitive decline that is not part of normal aging are described. Screening of older asymptomatic adults for cognitive decline and practical suggestions for the delivery of person-centered hearing care are discussed. Holistic management goals, personhood, and person-centered care in hearing care management are considered for older adults with normal cognitive aging through to dementia. A case study illustrates important skills and potential management methods. Prevention strategies for managing hearing and cognitive health and function through to older age, and strategies to maximize successful hearing aid use are provided. Conclusion: This article provides evidence-based recommendations for hearing care professionals supporting older clients to maximize well-being through the cognitive trajectory. [ABSTRACT FROM AUTHOR]

Purpose: The Rehabilitation Interventions for Individuals with a Spinal Cord Injury in the Community (RIISC) team aimed to develop and evaluate innovative rehabilitation interventions to identify endocrine metabolic disease (EMD) risk, intending to reduce the frequency and severity of EMD related morbidity and mortality among adults living with chronic spinal cord injury or disease (SCI/D). Materials and Methods: An interprovincial team from Ontario and Quebec reviewed available EMD literature and evidence syntheses and completed an inventory of health services, policies and practices in SCI/D care. The review outcomes were combined with expert opinion to create an EMD risk model to inform health service transformation. Results: EMD risk and mortality are highly prevalent among adults with chronic SCI/D. In stark contrast, few rehabilitation interventions target EMD outcomes. The modelled solution proposes: 1) abandoning single-disease paradigms and examining a holistic perspective of the individual's EMD risk, and 2) developing and disseminating practice-based research approaches in outpatient community settings. Conclusions: RIISC model adoption could accelerate EMD care optimization, and ultimately inform the design of large-scale longitudinal pragmatic trials likely to improve health outcomes. Linking the RIISC team activities to economic evaluations and policy deliverables will strengthen the relevance and impact among policymakers, health care providers and patients. IMPLICATIONS FOR REHABILITATION: Living with a spinal cord injury or disease (SCI/D) increases endocrine metabolic disease (EMD) risk. EMD-related outcomes include fracture; type II diabetes; and cardiovascular disease (myocardial infarction, sudden cardiac death and stroke), directly contributing to higher morbidity and mortality. Single-disease paradigms are not the ideal strategy to address multimorbidity contexts experienced in SCI/D. Practice-based research could be an alternative/adjunct to randomized control trials at generating evidence on current and emerging rehabilitation approaches. [ABSTRACT FROM AUTHOR]

Background: The Drug and Violence Resistance Educational Program (Programa Educacional de Resistência às Drogas e à Violência – PROERD) is the most widely implemented prevention program in Brazil and this study evaluated the reasons and ways in which PROERD instructors change the program, affecting its implementation fidelity. Methods: This qualitative method study used three data sources: semi-structured interviews with 19 police officers (PROERD instructors), fidelity forms completed by the instructors, and the researcher's observations of 30 lessons, followed by thematic analysis. Results: Strong evidence shows that instructors adapt the program, in general, because they experienced that some activities do not work when implemented as they were created by the developers. The main reasons to adapt the program were categorized into two groups: intrinsic and extrinsic reasons. The cultural reality and school performance of students and the support and infrastructure of the school were the extrinsic reasons, and instructors' performance was the intrinsic reason. Conclusion: In order to make PROERD feasible for students and schools, instructors change the program in an unstructured way, often not following the curriculum. Therefore, PROERD will hardly have a positive effect for Brazilian students. [ABSTRACT FROM AUTHOR]

Introduction: Cholesteryl ester transfer protein (CETP) plays an important role in lipid metabolism. Early interest in the development of CETP inhibitors proved to be disappointing. Recent interest has focused on the potential for CETP inhibition to reduce cardiovascular risk by lowering levels of low-density lipoprotein cholesterol (LDL-C). Areas covered: The data suggesting that low CETP activity may associate with lower levels of cardiovascular risk and early experience with CETP inhibitors focused on raising HDL-C levels. More recent data that suggests that any potential to reduce cardiovascular risk by inhibition of CETP is more likely to result from lowering levels of atherogenic lipid parameters. The development of obicetrapib, a potent CETP inhibitor, with robust lowering of apoB and LDL-C, will be summarized as a potential approach to the prevention of cardiovascular disease. Expert opinion: Obicetrapib is a potent CETP inhibitor, with a demonstrated ability to lower levels of apoB and LDL-C as monotherapy and in addition to high intensity statin therapy. The ultimate impact of obicetrapib on cardiovascular events will be evaluated by ongoing clinical trials. [ABSTRACT FROM AUTHOR]

AbstractMental health issues among children and adolescents have increased, especially after the COVID-19 pandemic. Despite awareness, less than half get needed care, leading to long-term consequences. The World Health Organization calls for integrated, preventive community interventions. In this paper, we present The Mental Health Clinical Liaison Programme for Schools in the Community of Madrid, Spain, which features school-based activities delivered by multidisciplinary mental health teams, offering early detection, intervention, and prevention strategies for children and adolescents. We describe the activities implemented, present the evidence supporting them, provide preliminary data, and discuss the scope and challenges of the programme. In 2023–2024, the programme intervened in 53 primary and secondary schools, helping identify in 876 cases, evaluating 356, and referring 122 to other services. It supported interventions for 179 patients already in mental healthcare and 34 reintegrations after psychiatric hospitalization. Anti-stigma workshops have been conducted, involving approximately 1620 students. Ongoing research aims to evaluate the effectiveness and cost-effectiveness of these interventions to ensure continuous improvement in mental health services for young people. [ABSTRACT FROM AUTHOR]

Syndemic theory proposes that co-occurring, mutually reinforcing psychosocial challenges (mental health, substance use, minority stress [discrimination/stigma], abuse, unmet basic needs) drive HIV risk behavior and create barriers to care for marginalized populations. It is thus necessary to address this holistic, complex picture in HIV prevention. Emergency department (ED) visits are a prime opportunity to engage key risk groups, given their low engagement in regular clinic-based care and high utilization of drop-in care via EDs. Yet, EDs are overburdened and under-resourced; mHealth may be a vehicle for intervention delivery in this context. This study aimed to 1) characterize demographics, syndemic profiles, and HIV risk behavior among ED patients and 2) assess the acceptability of addressing syndemic issues, particularly via an mHealth approach, in the ED. A sample of N = 198 ED patients with an indication of HIV risk completed a cross-sectional psychosocial assessment. Descriptive statistics and bivariate correlations between syndemic issues were examined. Patients presenting to the ED reported marginalized identities and complex syndemic profiles including mental health issues (77%), at risk substance use (30%), childhood abuse (35%), adult abuse (31%), minority stress (63%), and unmet basic needs (37%). Over half the sample reported at least three syndemic issues (54%). All syndemic issues were significantly correlated with each other, supporting a synergistic nature. The sample reported indicators of HIV risk including lack of PrEP awareness (33%)/uptake (94%), condomless sex (37%), and not testing for HIV (41%). Majority reported syndemic profiles have never been addressed in the ED (71%), think it would be helpful (88%), and willing to utilize mHealth during an ED visit (76%). The current study provides information to guide next steps for ED-based point-of-care HIV prevention, and more broadly, working towards equitable HIV prevention services reaching those missed by existing interventions. [ABSTRACT FROM AUTHOR]

AbstractBackground and Objectives: We examined associations between sources of social influence (i.e. close friends, other underage people present) within specific settings with the number of drinks underage youth consumed. Methods: Data were collected through a cross-sectional survey with 422 underage youth in California (14 to 19 years old) who reported past-6-month alcohol use. Participants were asked to think about the last time they drank alcohol in the past 6 months at: restaurants, bars/nightclubs, own home, another’s home, outdoors, and fraternities/sororities. Outcomes were the number of whole drinks participants drank the last time in each setting. Independent measures were social characteristics of these drinking events including number of people <21 years old present, number of close friends present, number of <21 years old who consumed alcohol, and number of close friends who consumed alcohol. We also assessed socio-demographics and accounted for the overall exposure to each setting in the past 6 months. Results: Using negative binomial regression models, the number of close friends was positively associated with number of drinks consumed at restaurants, another’s home, and outdoors. The number of close friends drinking was positively associated with the number of drinks at restaurants, own home, another’s home, and outdoors. Number of people <21 years old was positively associated with number of drinks at own home, and number of people <21 years old who consumed alcohol was positivity associated with number of drinks consumed at restaurants, own home, another’s home, and outdoors. Conclusions: Results suggest that social influence from close friends and from other underage youth are context-specific. [ABSTRACT FROM AUTHOR]

AbstractObjectivesMethodResultsConclusionThe use of digital healthcare technologies to enhance healthcare delivery has seen significant growth. However, a notable a notable research gap exists in the application of clinical scales for menopause management by general practitioners (GPs). This study aims to investigate willingness of GPs to use specific menopausal scale tools in the care of females for menopause management.An anonymous online survey was developed, which received responses from 348 French GPs in 2023. Multiple backward logistic regression was performed to identify the factors influencing the willingness to use a practical menopause management scale.In total, 87.93% of GPs are not familiar with the Greene Climacteric Scale and 90.52% are not familiar with the Menopause Quick 6 scale. In contrast, 90.52% would be interested in having access to such scales. The willingness to use a menopause management scale is associated with caring for menopausal females (odds ratio [OR] = 6.13, 95% confidence interval [CI] [2.08–18.08], p = 0.001), less experience (OR = 7.10, 95% CI [2.05–25.22], p = 0.002), the importance of health prevention in daily practice (comparing ‘very important’ to ‘not’, OR = 12.98, 95% CI [1.68–97.60], p = 0.004) and the use of a digital scale in daily practice for menopausal management (OR = 2.13, 95% CI [1.04–5.83], p = 0.014).Future research is essential in representative population to confirm these findings in menopause management. [ABSTRACT FROM AUTHOR]

Intervention mapping (IM) is a planning approach that reflects the intricate decision-making process involved in the design of behavior interventions. The development and implementation of IM is complex in preventing HIV/AIDS transmission. Therefore, it is significant to conduct a perfect preliminary work to successfully implement HIV/AIDS prevention. The objectives of this review were to collect and evaluate the data of the first three steps using IM to prevent HIV/AIDS transmission, and summarize the key points in the preliminary steps of IM. A total of 18 studies were identified, and six studies completely described the tasks in the first three steps of IM. Three studies described the logic model of the problem (n = 3). Six studies reported the matrix of behavior changes (n = 6), including personal and environmental determinants. Among the selected determinants, most studies reported the personal level determinants (self-efficacy and skills, knowledge, attitudes, and norms). The most used practical applications in reducing HIV/AIDS risk behaviors were video roles (n = 8) and role-model stories (n = 5). The review may be helpful for healthcare professionals to carefully design and implement the key procedures of the first three steps of the IM programs for people with HIV/AIDS in preventing HIV/AIDS transmission. [ABSTRACT FROM AUTHOR]

Intestinal inflammation modifies host physiology to promote the occurrence of colorectal cancer (CRC), as seen in colitis-associated CRC. Gut microbiota is crucial in cancer progression, primarily by inducing intestinal chronic inflammatory microenvironment, leading to DNA damage, chromosomal mutation, and alterations in specific metabolite production. Therefore, there is an increasing interest in microbiota-based prevention and treatment strategies, such as probiotics, prebiotics, microbiota-derived metabolites, and fecal microbiota transplantation. This review aims to provide valuable insights into the potential correlations between gut microbiota and colitis-associated CRC, as well as the promising microbiota-based strategies for colitis-associated CRC. [ABSTRACT FROM AUTHOR]

The oral cavity contains a site-specific microbiota that interacts with host cells to regulate many physiological processes in the human body. Emerging evidence has suggested that changes in the oral microbiota can increase the risk of lung cancer (LC), and the oral microbiota is also altered in patients with LC. Human and animal studies have shown that oral microecological disorders and/or specific oral bacteria may play an active role in the occurrence and development of LC through direct and/or indirect mechanisms. These studies support the potential of oral microbiota in the clinical treatment of LC. Oral microbiota may therefore be used in the prevention and treatment of LC and to improve the side effects of anticancer therapy by regulating the balance of the oral microbiome. Specific oral microbiota in LC may also be used as screening or predictive biomarkers. This review summarizes the main findings in research on oral microbiome-related LC and discusses current challenges and future research directions. [ABSTRACT FROM AUTHOR]

The aims of the study were to build models using logistic regression analysis of flexibility and strength tests to prospectively predict risk factors for anterior cruciate ligament tear (ACL-tear) in female soccer (FS) players, and to determine training cut-off for risk factors of the predictive model built. A prospective cohort study of 95 female players (aged 14–33 years) was conducted. Age, anthropometric data, soccer history, lower limb range of motion (ROM) and hip maximal isometric strength (MIS) were measured. At the prospective follow-up after 12 months, 7.4% of the players had developed an ACL-tear. The model showed a significant relationship (χ2(93) = 30.531, p < 0.001) between the ACL-tear and the predictor variables (leg length, HAD-NH [hip adduction] MIS, asymmetric ROM [ankle dorsiflexion with knee extended (AD-KE) and with knee flexed (AD-KF), and HE (hip extension)], hip ROM [HIR (internal rotation) and HAB (abduction)]). The Akaike Information Criteria (AIC) and Bayesian Information Criteria (BIC) for model fit were 30.24 and 51.79, respectively. The value R2 showed good model fit, 76.5% for Nagelkerke´s R2, 71.4% for McFadden´s R2 and 67.5% for Tjur´s R2. For the screening test, cut-off for leg length of ≥0.40 m, for HIR ROM of ≤44º and for asymmetry of HE ROM of ≥5° were set, which have an acceptable (AUC ≥ 0.755) discriminatory ability for the development of ACL-tear. [ABSTRACT FROM AUTHOR]

The aim was to present a descriptive 10-season summary of injury data from all teams of a professional football club using a heat map approach. Injuries and exposure time were registered according to the FIFA consensus in all men's and women's teams from Athletic Club over 10 seasons. A team-by-injury table was created, showing the incidence, median severity, and burden in each cell. Cells were coloured based on the injury burden value using a green – yellow–red gradient (lowest to highest). The highest overall injury burden was found in the women's 2nd and 1st teams and the men's U(under)17 team (>200 days lost/1000 h). Muscle injury burden demonstrated an increasing pattern with age. Knee joint/ligament injuries, particularly anterior cruciate ligament ruptures, had the highest impact on women's teams, followed by the men's 2nd team. In comparison, ankle joint/ligament injuries had a relatively low injury burden in most teams. Growth-related injuries were the most impactful injuries in the men's U15 and younger teams, and the women's U14 team. In conclusion, epidemiological data on injuries can inform and guide injury management processes. New and improved visualization methods might be important assets when presenting injury data to key decision-makers. [ABSTRACT FROM AUTHOR]

Global warming will lead to more frequent and intense heatwaves across all regions of the world in the coming decades. Adaptation at the individual level plays a key role in helping populations cope with these extreme events. This study undertakes a systematic review of the academic literature on the determinants of heat-adaptive behaviours (HABs) following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. A Boolean algorithm was used on two online databases (PubMed and Web of Science Core Collection) to retrieve 73 relevant, quantitative, peer-reviewed papers. All included studies focus on high-income economies (N = 48) or middle-income economies (MIEs, N = 25). A meta-analysis was performed on 34 studies using a random-effects model, with an emphasis on heat-related perceptions (perceived efficacy, risk and threat) and heat-related knowledge (HRK), as these variables are the most likely levers of behavioural change. Perceived efficacy, HRK, perceived threat and gender (i.e. being female) are positively associated with the adoption of HABs. A moderation analysis reveals heterogeneity in the effect of these variables by country income group, with low HRK and perceived threat constituting stronger barriers to HABs in MIEs. This study also highlights various gaps in the current literature, regarding the populations studied, the statistical methods used, and the lack of standardization of HABs and perception concepts. Key policy insights: Heat-adaptive behaviours (HABs) are influenced by both psychological and non-psychological factors. Information and communication campaigns may be designed to influence the determinants of psychological factors and use them as adaptation levers. Policymakers should implement information campaigns to underline the characteristics and adverse health effects of heatwaves, as well as reminding people of ways to cope with heatwaves, especially in middle-income economies (MIEs). Information and prevention campaigns in MIEs should clearly highlight the frequency and severity of the health hazards associated with heatwaves in order to improve public awareness of these risks. Information campaigns based on simple infographics showing the most effective HABs and reminding people of the efficacy of HABs to reduce heatwave health risks may be especially impactful in high-income economies. [ABSTRACT FROM AUTHOR]

The nationally funded Prevention and Early Intervention (PEI) programme aimed to design, deliver and evaluate interventions to improve a range of outcomes for children growing up in areas of low socio-economic status (SES). A key focus for many PEI programmes was to improve the oral language abilities of children, recognising its important link to a range of literacy, learning, social, emotional and behavioural indicators. This paper reviewed the published reports of PEI and community programmes that implemented oral language interventions for children, parents and practitioners. This mapping exercise demonstrated that the oral language interventions implemented varied extensively and were predominantly evaluated through gathering the perspectives of those receiving the supports. A noticeable gap was the lack of a national evaluation framework of the oral language interventions provided, resulting in difficulties making comparisons, determining impact and contributing to the evidence base of the effectiveness of bespoke interventions designed and delivered. Implications of this mapping exercise are outlined for the future implementation and evaluation of universal and targeted oral language interventions. [ABSTRACT FROM AUTHOR]

Distributed Denial of Service (DDoS) attacks constitute a formidable threat, obstructing access to legitimate internet services and disrupting the seamless provision of services by organizations. Despite extensive research dedicated to developing defense mechanisms against DDoS attacks, their persistence remains a challenge. The majority of research in DDoS defense can be categorized into attack detection, mitigation, and prevention. Notably, defense strategies falling within the purview of attack detection and mitigation are reactive in nature, often activated after some level of damage has already occurred. In addition, the terms "detection" and "mitigation," maintain consistent meanings in the literature. However, the term "prevention" in the context of DDoS attacks has been associated with varying interpretations in the literature. This paper undertakes a comprehensive review of techniques labeled as "prevention" in the realm of DDoS attacks. In addition, because prevention techniques do not have a standard meaning in the literature, we further classify these techniques into Ideal Prevention, True Prevention, and Partial Prevention. By scrutinizing these techniques and their implications, we shed light on the complexity of mitigating DDoS threats effectively. In particular, we advocate for increased focus on True Prevention techniques, emphasizing the need for dynamism, computational efficiency, scalability, and practical deployability. [ABSTRACT FROM AUTHOR]

This article engages with the restoration of broken resilience in Dutch secondary radicalisation prevention programmes. It demonstrates the simultaneity of disciplinary techniques and affective governance in case management captured through the concept of "affective discipline". Affective discipline consists of four elements: 1) Surveillance and affective engagement, 2) a pre-conceived ideal, i.e. a norm of what it means to be resilient, 3) measures benefitting compliance and punishing non-compliance, and 4) affective discipline also disciplines the affective relations of those in the programme, as the aim is to restore a sense of belonging and a sense of cultural identity. The article positions resilience as affective discipline within a broader turn of affective governmentality, focusing on the disciplinary aspects of the governance of and through affect. [ABSTRACT FROM AUTHOR]

Background: Medication disposal programs have been promoted as one solution to the opioid crisis, but uptake by community members has been minimal.Objectives: To clarify perceptions of medication disposal options among people who have been prescribed an opioid analgesic in North Carolina to inform interventions that can facilitate the disposal of unused opioids.Methods: In 2022, we conducted focus groups with participants who received an opioid medication in the past year to gain information to develop an intervention related to the disposal of unused opioid medication (12 focus group discussions (FGDs); total N = 37; 30 identified as female, 6 as male, and 1 as another gender). Participants were shown a slide with the Food and Drug Administration’s recommended disposal options and asked about their perceptions of each option. Themes were derived using an inductive, thematic, qualitative approach.Results: Seven themes about perceptions of medication disposal programs emerged from the data. Four of the themes reflect potential barriers to medication disposal: failed disposal attempts, lack of sufficient education on proper disposal, unclear meaning of specific disposal language, and concerns about existing disposal options. Three of the themes provide insight on potential facilitators of medication disposal: preference of low-cost disposal options, ease and accessibility among disposal methods, and preferred disposal methods.Conclusion: Patients should be provided clear and consistent guidance from prescribers and dispensing pharmacists on when and how to dispose of unused medications and opportunities to dispose of medications at no cost to the patient. [ABSTRACT FROM AUTHOR]

AbstractObjectiveMethodsResultsConclusions\nHIGHLIGHTSWorldwide helplines are considered an important part of suicide prevention strategies. Nevertheless, evidence regarding the impact of suicide prevention helplines on the suicidality of its users remains limited and is frequently confronted with methodological issues. This study aimed to assess the impact of crisis calls on callers’ levels of crisis and suicidality both immediately after the call and at follow-up compared to before the call. After the call, the satisfaction of the callers with the intervention was also assessed.A pre-post study, generated automatically by a telephone system, was conducted in order to compare the level of crisis and suicidality (operationalized by five indicators: hopelessness, entrapment, controllability, suicidal intent, and social support) experienced by callers before and immediately after the call and at follow-up (one to two weeks after the call).Callers (n = 487) showed significant improvement in their level of crisis (p < .001, d = −0.31), hopelessness (p < .001, d = −0.22), entrapment (p < .001, d = −0.25), suicide intent (p < .001, d = −0.37), and social support (p < .001, d = 0.33) after the call compared to before the call. Improvements were also found at follow-up compared to pretest. The satisfaction of callers with the helpline was high.This study adds to the growing evidence on suicide prevention helplines and addresses some important methodological issues in helpline research. Furthermore, it shows promising results regarding the potential supportive impact of helplines on callers who feel suicidal.Crisis helpline research is limited and often confronted with methodological issuesCallers improve in experienced levels of crisis, hopelessness, entrapment, supportStudy shows potential of helplines to positively influence individuals in crisisCrisis helpline research is limited and often confronted with methodological issuesCallers improve in experienced levels of crisis, hopelessness, entrapment, supportStudy shows potential of helplines to positively influence individuals in crisis [ABSTRACT FROM AUTHOR]

The ongoing multi-country mpox outbreak in previously unaffected countries is primarily affecting sexual networks of men who have sex with men. Evidence is needed on the effectiveness of recommended preventive interventions. To inform WHO guidelines, a systematic review and qualitative evidence synthesis were conducted on mpox preventive behavioural interventions to reduce: (i) sexual acquisition; (ii) onward sexual transmission from confirmed/probable cases; and (iii) utility of asymptomatic testing. Medline, EMBASE, PubMed, Cochrane and WHO trial databases, grey literature and conferences were searched for English-language primary research published since 1 January 2022. A reviewer team performed screening, data extraction and bias assessment. A qualitative thematic synthesis explored views and experiences of engagement in prevention in individuals at increased risk. There were 16 studies: 1 on contact-tracing, 2 on sexual behaviour, and 13 on asymptomatic testing. Although MPXV was detected in varying proportions of samples (0.17%–6.5%), the testing studies provide insufficient evidence to fully evaluate this strategy. For the qualitative evidence synthesis, four studies evaluated the experiences of most affected communities. Preferences about preventive interventions were shaped by: mpox information; the diversity of sexual practices; accessibility and quality of mpox testing and care; and perceived cost to wellbeing. Evidence on the effectiveness of interventions to prevent the sexual transmission of mpox remains scarce. Limited qualitative evidence on values and preferences provides insight into factors influencing intervention acceptability. Given global and local inequities in access to vaccines and treatment, further research is needed to establish the effectiveness of additional interventions. [ABSTRACT FROM AUTHOR]

The current study evaluates a single-day youth-designed sexual assault prevention summit for adolescents. Attendees (N = 284) completed pre-and post-summit surveys addressing 1) confidence in consent knowledge; 2) perceived capability to respond to someone who was assaulted or harassed; 3) awareness of Title IX rights; 4) perceived capacity to get help for a survivor; 5) perceived acceptability of sexual coercion; 6) endorsement of belief that it is wrong to stop sexual activity once it starts; 7) perceived seriousness of sharing nude photos without permission; and, 8) perceived prevalence of false accusations of sexual violence. At post-summit, participants reported increased perceived confidence in consent knowledge, increased perceived capacity to respond to a survivor, increased awareness of Title IX rights, and increased perceived capacity to get help for a survivor. Both perceived acceptability of sexual coercion and endorsement of the belief that someone should not stop sexual activity decreased at post-summit. Findings provide preliminary support for a youth-developed sexual assault prevention summit. [ABSTRACT FROM AUTHOR]

Medication nonadherence is common and results in avoidable morbidity, mortality, and burdens on healthcare systems. This paper proposes a preventative approach to medication nonadherence. We consider existing evidence on the prevalence and determinants of nonadherence early in a patient’s medication-taking journey, and map these to potential opportunities for intervention. Many patients stop taking a new medication soon after they are prescribed it, often not collecting the medication. Early patterns of nonadherence are linked to later nonadherence via processes such as habit formation and symptom experiences. Known predictors of nonadherence may be present before someone starts a new treatment, when patients experience disruption to their lives and identity due to illness. Healthcare professionals typically have contact with patients around this time. We argue that it may be possible to prevent medication nonadherence: at the population level; by optimising the prescription process; and through low- and high-intensity interventions for patients with identified early barriers. We give examples of specific interventions and tools that might be needed to operationalise this approach in practice and propose new directions for research to promote early engagement with medication to prevent nonadherence. [ABSTRACT FROM AUTHOR]

Ovarian cancer is an aggressive malignancy and the leading cause of death among gynecologic cancers. Researchers have evaluated prophylactic medications that potentially avert the manifestation of ovarian cancer, but currently, there are no reliable screening measures for this disease. Nevertheless, the largest study involving aspirin use and ovarian cancer reported a substantive risk reduction from enduring aspirin use. Since there are countervailing data to impugn the potential benefits of aspirin use in staving off ovarian cancer, further research should scrutinize the use of this medication as a prophylactic intervention, especially in women who are at higher risk for developing the disease. [ABSTRACT FROM AUTHOR]

Men who have sex with men (MSM) are disproportionately affected by HIV. Given that over 70% of MSM meet sexual partners via dating apps, such apps may be an effective platform for promoting HIV pre-exposure prophylaxis (PrEP) use. We aimed to describe preferences among MSM for PrEP advertisements displayed on dating apps. We conducted individual in-depth interviews with 16 MSM recruited from a mobile sexual health unit in Boston, Massachusetts. Two focus groups were also held: one with mobile unit staff (N = 3) and one with mobile unit users (N = 3). Content analysis was used to identify themes related to advertisement content and integration with app use. Mean participant age was 28 (SD 6.8); 37% identified as White and 63% as Latinx. 21% of interviews were conducted in Spanish. Preferences were organized around four themes: (1) relevant and relatable advertisements, (2) expansion of target audiences to promote access, (3) concise and captivating advertisements, and (4) PrEP advertisements and services as options, not obligations. MSM are supportive of receiving information about PrEP on dating apps, but feel that existing advertisements require modification to better engage viewers. Dating apps may be an underutilized tool for increasing PrEP awareness and knowledge among MSM. [ABSTRACT FROM AUTHOR]

With commercial casinos proliferating over the past two decades, gambling-related harm has attracted attention in terms of both research and development of treatment strategies. A problematic relationship with gambling has major consequences for gamblers, families, communities, and society. This paper aims to present a better understanding of Chinese migrants' experiences of responding to casino gambling harm in New Zealand using an interpretive phenomenological approach. Sixteen recent Chinese migrants were interviewed: eight people who self-identified as gambling problematically and eight affected family members. Data analysis incorporated a thematic approach involving multiple readings of interview transcripts and iterative processing of developing themes. The key findings are organized into a model involving four stages: misconnection (pathways into excessive gambling), disconnecting (moving away from casino gambling), reconnection (settling into their new social environment), and rebuilding a 'natural life' (a Chinese cultural conception of recovery). This process model helps understanding the Chinese migrants' experience of responding to gambling harm in a broad social-cultural-historical context. [ABSTRACT FROM AUTHOR]

A cross-sectional case–control study compared subjective knee function, quality of life and radiographic knee osteoarthritis (OA) between 45 former elite football players and an age-matched general male population. Participants completed the Knee OA Outcome Score (KOOS), a quality-of-life assessment (EQ-5D-3 L) and standing knee radiographs. Among the players, 24 (53%) sustained at least one moderate or severe knee injury, while 21 (47%) did not recall any injury. Players with previous knee injuries reported significantly lower knee-specific and general quality-of-life scores (KOOS 69; EQ-5D-3 L 0.69 (0.2)) compared to the non-injured players (KOOS 92; EQ-5D-3 L 0.81 (0.2)) or the control population (KOOS 90; EQ-5D-3 L 0.83 (0.2)). The injured knees had higher radiographic OA Kellgren-Lawrence (KL) scale grades 1.7 (1.3) than the knees of the non-injured players 0.8 (1.0) or the control knees 0.8 (1.0) Former elite football players who had previously sustained a moderate or severe knee injury reported inferior knee function and lower quality of life. Injured knees had higher levels of radiographic OA. Non-injured players reported similar knee and general function and their knees had similar grades of OA to those in the control group. The defining moment for long-term knee preservation in football should be injury prevention protocols. [ABSTRACT FROM AUTHOR]

This paper reports an analysis using the computable general equilibrium (CGE) model to calculate the economic development and emissions under different air pollution prevention strategies, with a focus on the Beijing-Tianjin-Hebei rim surrounding the cities in the 'Capital Economic Circle'. It appeared that raising the emission tax effectively suppressed air pollution but also suppressed economic development. Raising the emission subsidy promoted economic development, but did not suppress air pollution. A stepwise tax collection mode can be used to formulate the emission tax. When using emission subsidies to encourage manufacturers to improve their exhaust treatment technology, the policy should be tilted towards small enterprises to reduce economic pressure on them. [ABSTRACT FROM AUTHOR]

Micronutrient deficiencies or "hidden hunger" remains a serious public health problem in most low- and middle-income countries, with severe consequences for child development. Traditional methods of treatment and prevention, such as supplementation and fortification, have not always proven to be effective and may have undesirable side-effects (i.e., digestive troubles with iron supplementation). Commensal bacteria in the gut may increase bioavailability of specific micronutrients (i.e., minerals), notably by removing anti-nutritional compounds, such as phytates and polyphenols, or by the synthesis of vitamins. Together with the gastrointestinal mucosa, gut microbiota is also the first line of protection against pathogens. It contributes to the reinforcement of the integrity of the intestinal epithelium and to a better absorption of micronutrients. However, its role in micronutrient malnutrition is still poorly understood. Moreover, the bacterial metabolism is also dependent of micronutrients acquired from the gut environment and resident bacteria may compete or collaborate to maintain micronutrient homeostasis. Gut microbiota composition can therefore be modulated by micronutrient availability. This review brings together current knowledge on this two-way relationship between micronutrients and gut microbiota bacteria, with a focus on iron, zinc, vitamin A and folate (vitamin B9), as these deficiencies are public health concerns in a global context. [ABSTRACT FROM AUTHOR]

Mycotoxins, secondary metabolites produced by mycotoxigenic fungi, are a major problem affecting food safety and security, because of their adverse health effects, their socio-economic impact and the difficulty of degradation or removal by conventional food processing methods. Plant-sourced natural products are a novel and effective control method for fungal infestation and mycotoxin production, with the advantages of biodegradability and acceptability for food use. However, development of resistance, low and inconsistent efficacy, and a limited range of antifungal activities hinder the effective application of single plant natural products for controlling mycotoxin contamination. To overcome these limitations, combinations of plant natural products have been tested extensively and found to increase efficacy, often synergistically. However, this extensive and promising research area has seen little development of practical applications. This review aims to provide up-to-date information on the antifungal, anti-mycotoxigenic and synergistic effects of combinations of plant natural products, as well as their mechanisms of action, to provide a reference source for future research and encourage application development. [ABSTRACT FROM AUTHOR]

Cardiopulmonary bypass (CPB) is a common technique in cardiac surgery but is associated with acute kidney injury (AKI), which carries considerable morbidity and mortality. In this review, we explore the range and definition of CPB-associated AKI and discuss the possible impact of different disease recognition methods on research outcomes. Furthermore, we introduce the specialized equipment and procedural intricacies associated with CPB surgeries. Based on recent research, we discuss the potential pathogenesis of AKI that may result from CPB, including compromised perfusion and oxygenation, inflammatory activation, oxidative stress, coagulopathy, hemolysis, and endothelial damage. Finally, we explore current interventions aimed at preventing and attenuating renal impairment related to CPB, and presenting these measures from three perspectives: (1) avoiding CPB to eliminate the fundamental impact on renal function; (2) optimizing CPB by adjusting equipment parameters, optimizing surgical procedures, or using improved materials to mitigate kidney damage; (3) employing pharmacological or interventional measures targeting pathogenic factors. [ABSTRACT FROM AUTHOR]

To investigate the preventive effect of aerobic exercise on renal damage caused by obesity. The mice in the Control (Con) and Control + Exercise (Con + Ex) groups received a standard chow diet for the 21-week duration of the study, while the High-fat diet (HFD) group and High-fat diet + Exercise (HFD + Ex) group were fed an HFD. Mice were acclimated to the laboratory for 1 week, given 12 weeks of being on their respective diets, and then the Con + Ex and HFD + Ex groups were subjected to moderate intensity aerobic treadmill running 45 min/day, 5 days/week for 8 weeks. We found that HFD-induced obesity mainly impacts kidney glycerin phospholipids, glycerides, and fatty acyls, and aerobic exercise mainly impacts kidney glycerides, amino acids and organic acids as well as their derivatives. We identified 18 metabolites with significantly altered levels that appear to be involved in aerobic exercise mediated prevention of HFD-induced obesity and renal damage, half of which were amino acids and organic acids and their derivatives. Aerobic exercise rewires kidney metabolites to reduce high-fat diet-induced obesity and renal injury. [ABSTRACT FROM AUTHOR]

Background and purpose: Unawareness of the risk factors is one of the most important issues that need to be settled for stroke prevention. We aimed to evaluate the awareness of risk factors for cerebrovascular diseases (CVDs) among acute ischemic stroke patients and to investigate the characteristics of patients who were unaware of their risk factors in Shenzhen, China. Methods: Registered data on awareness of CVD risk factors of patients with confirmed acute ischemic stroke (AIS) from June 2020 to December 2022 were analyzed in May 2023. The data were extracted from the database of Shenzhen Quality Control Center for Management of Cerebrovascular Diseases. Results: Totally, there were 5147 AIS patients with complete data eligible for this study. AIS patients' awareness regarding existing hypertension, diabetes, dyslipidemia, and atrial fibrillation (AF) was 76.1%, 76.2%, 24.2%, and 53.4%, respectively. Patients who were lack of awareness of the CVD risk factors were more likely to be males, individuals with younger ages, and those without medical insurance or a CVD history. Conclusions: The overall awareness of the CVD risk factors was suboptimal among AIS patients in Shenzhen, especially for the existing dyslipidemia. The health education of AIS should be further improved in males as well as individuals without medical insurance or any CVD histories. Age was an independent factor associated with the lack of awareness of the CVD risk factors. The stroke screening program should be extended to younger people. [ABSTRACT FROM AUTHOR]

The document discusses the increased risk of skin cancers, specifically basal-cell carcinomas (BCC) and squamous-cell carcinomas (SCC), in solid organ transplant recipients (SOTR) due to immunosuppression. Treatment primarily involves surgical excision, with adjuvant radiotherapy for aggressive SCC. Immune-checkpoint inhibitors (ICI) are used for advanced SCC in non-immunosuppressed patients, but their use in SOTR requires careful consideration due to the risk of allograft rejection. Prevention strategies include treating precancerous lesions and implementing photoprotection measures. Future perspectives include new immunotherapies, HPV vaccination, and local blockade of tacrolimus for tumor rejection. [Extracted from the article]

Technology-facilitated child sexual abuse (TF-CSA), or child sexual abuse that occurs online or through electronic communication, is a preventable public health problem that can be addressed within youth-serving organizations (YSOs). This study is a review of a purposive sample of organizational policies and practices designed to prevent TF-CSA collected from 13 national and local YSOs in the United States. Documents were coded to identify practices to prevent TF-CSA related to YSO activities or YSO staff, volunteers, or participants. Qualitative analysis indicated that YSOs included seven common practices to prevent TF-CSA in their documents. These practices included transparent electronic communication between youth and YSO staff; codes of conduct and online behavior agreements related to youth; monitoring the YSO’s online presence; parental controls for youth online activity; safety behaviors for online activity for staff, parents, and youth; parent and youth trainings for youth online engagement and prevention of TF-CSA; and practices to address staff policy violations. Most prevention practices documented by YSOs identified in this study are consistent with emerging literature on TF-CSA prevention. Key gaps include protections for youth from groups inequitably burdened by TF-CSA and evaluation of the implementation and effectiveness of practices in preventing TF-CSA across settings and populations. [ABSTRACT FROM AUTHOR]

AbstractStunting, a consequence of chronic malnutrition, has detrimental effects on child development. This qualitative study explores socio-cultural factors and family practices related to stunting prevention in food-insecure areas of West Timor, Indonesia. Data were collected through in-depth interviews, questionnaires, focus groups, and observations with mothers (n = 20), healthcare workers, officials, traditional figures, and religious leaders. Identified parenting practices spanned childcare, immunization, hygiene, sick child care, and feeding. Support for pregnant and postpartum mothers was crucial. Socio-cultural influences emerged in three themes: child food intake, care during pregnancy, and maternal care after childbirth. This study underscores the combined impact of food insecurity and socio-cultural factors on stunting. Culturally sensitive interventions addressing food availability and these practices are essential for effective stunting prevention. [ABSTRACT FROM AUTHOR]

Dementia is a debilitating condition with a disproportionate impact on women. While sex differences in longevity contribute to the disparity, the role of the female sex as a biological variable in disease progression is not yet fully elucidated. Metabolic dysfunctions are drivers of dementia etiology, and cardiometabolic diseases are among the most influential modifiable risk factors. Pregnancy is a time of enhanced vulnerability for metabolic disorders. Many dementia risk factors, such as hypertension or blood glucose dysregulation, often emerge for the first time in pregnancy. While such cardiometabolic complications in pregnancy pose a risk to the health trajectory of a woman, increasing her odds of developing type 2 diabetes or chronic hypertension, it is not fully understood how this relates to her risk for dementia. Furthermore, structural and functional changes in the maternal brain have been reported during pregnancy suggesting it is a time of neuroplasticity for the mother. Therefore, pregnancy may be a window of opportunity to optimize metabolic health and support the maternal brain. Healthy dietary patterns are known to reduce the risk of cardiometabolic diseases and have been linked to dementia prevention, yet interventions targeting cognitive function in late life have largely been unsuccessful. Earlier interventions are needed to address the underlying metabolic dysfunctions and potentially reduce the risk of dementia, and pregnancy offers an ideal opportunity to intervene. This review discusses current evidence regarding maternal brain health and the potential window of opportunity in pregnancy to use diet to address neurological health disparities for women. [ABSTRACT FROM AUTHOR]

Domestic and community violence are two pervasive societal issues. While research indicates significant connections between these forms of violence, detailed exploration of their co-occurrence and specific characteristics within intervention and prevention programs remains lacking. Understanding these complex interactions is crucial, as many programs are not designed to address the diverse manifestations of violence simultaneously. They often focus on one type, potentially overlooking the broader spectrum of violence that individuals might experience or contribute to. This study aims to illuminate the frequency and nature of these violence types within the context of intervention efforts. To bridge this gap, we engaged in a systematic, secondary analysis, delving into 1,943 conflicts documented across 25 CeaseFire program sites in Chicago between 2000 and 2015. Data included information from mediation forms regularly completed by CeaseFire staff post-mediation. Our primary focus encompassed a content analysis of these cases to establish a baseline occurrence of domestic violence within violence mediations. Subsequently, we probed the prevalence and intricate interplay between community and domestic violence, exploring potential bidirectional influences. Of the 1,943 conflicts mediated among program sites in Chicago, 151 conflicts displayed signs of interconnection with community violence, falling into the categories of retaliation or intervention. In summation, the findings underscore the entwined nature of domestic and community violence, often transitioning from one form (primarily domestic) to another (typically community-based) in the form of escalating retaliatory behaviors. Violence prevention and intervention endeavors must consider the plausible escalation patterns stemming from interconnected violence forms, significantly shaping mediation strategies. [ABSTRACT FROM AUTHOR]

Participation in outdoor sports increases exposure to ultraviolet radiation, necessitating mitigation through sunscreen use. This prospective study examined the effects of sport, setting (practice vs. competition), gender, age and geographic location on sunscreen use and education among youth athletes in various sports. Six hundred and twelve athletes ≤18 years old completed an online survey on sunscreen education and use during competitions and practices. Regardless of sport, reported sunscreen use was higher during practices than competition (p < 0.0001). Sunscreen was used most by swimmers/divers (odds ratio: OR ≥ 1.9, p < 0.001) and least by American football players (OR ≤ 0.57, p ≤ 0.001). Coaches mentioned sunscreen use the most in track and field (OR 1.84, p = 0.001) and the least in American football (OR 0.67, p = 0.03). Athletes used sunscreen more if they were female (OR ≥ 1.9 1.38, p ≤ 0.06) and younger (age OR ≤ 0.88, p < 0.001). In conclusion, youth athletes differ in sunscreen use by sport and setting, highlighting the need for continued photoprotective education. [ABSTRACT FROM AUTHOR]

Systemic use of Ivermectin has been reported to incite blindness in humans and veterinary patients. This study was designed to investigate the systemic and intravitreal effect of Ivermectin on ocular and retinal health and its attenuation with topical Dexamethasone. Systemic injection of Ivermectin@ 1.6 mg/kg S/C was administered, thrice a week for three weeks to New Zealand White rabbits (N = 4) with and without topical drops of Verapamil (N = 4). Pre and post-treatment ocular examination was conducted. At the end of three weeks the eyes were collected for histopathology. 0.2 ml of Ivermectin solution (1.6 mg/ml) was injected intravitreally in one eye of the rabbit (N = 8), Half the rabbits received 0.1% dexamethasone drops thrice daily for 7 days, while the controls received PBS. Pre and post-treatment, detailed examination was conducted, which included the Schirmer Tear test, Fluorescein staining, Intraocular pressure, slit lamp biomicroscopy and fundus photography. The retina was harvested for histopathological and tunnel assay. Systemic therapy with Ivermectin, with and without Verapamil did not incite any adverse response in the eye. Intravitreal Ivermectin evoked severe uveitis 4/4, cataract 3/4, corneal erosion 3/4 eyes and severe inflammatory response. Eyes that received dexamethasone were rescued from the adverse changes as demonstrated clinically, by histopathology and prevention of apoptosis. Intravitreal Ivermectin incites severe inflammatory response. Topical dexamethasone counters the ocular toxicity incited by Ivermectin. [ABSTRACT FROM AUTHOR]

Falls are the second most common cause of injury associated with mortality worldwide and an important type of blunt trauma, which forms a significant percentage of traumatic accidents and emergency department admissions. Falling from a tree is an important problem because of its effect on one's health owing to infirmity caused by injuries, most commonly spinal injuries, and the economic burden that accompanies it. A retrospective chart analysis was performed including all the patients with falls from heights who presented to a tertiary care hospital in South India during the summer months of 2018, 2019, and 2020. A structured case record form was used to capture information such as basic demographics, tree species, reason for climbing the tree, and mode of fall, along with the clinical profile, and outcomes from the cases selected from the emergency department registers and cross verified using ICD codes. Despite the existing lockdown due to COVID, an unusual increase in the number of patients getting admitted to the triage with a fall from tree was noted in the year 2020 compared to 2019 and 2018. The most common type of injuries sustained were spinal injuries. Burst fractures were leading types of fractures in the patients with spinal injury. The second most common type of injuries involved were of extremities, with lower extremities more than upper extremities. Two patients had inhospital mortality within 30 days. Falls from a tree are a neglected and preventable mechanism of trauma with a significant socio-economic impact, as most of the patients are young or middle aged earning members of their families. The burden of this mode of injury is primarily on rural and agricultural communities. Pre-hospital services in areas with vast agroforestry cultivation require dedicated first response clinics. Lockdowns and geographic isolation during disasters or disease outbreaks must also factor in a supply of essential commodities and warrant treatment on an urgent basis to reduce the need and risk of injury from forestry and agricultural activities. [ABSTRACT FROM AUTHOR]

The existing literature has focused little on the health-promoting role of resources for sleep. Mainly risk factors have been highlighted regarding mental health in general. Moreover, for the vulnerable age group of adolescents, resources and their relation to sleep have hardly been explored. Therefore, this study aims to investigate the predictive role of personal/social resources for the likelihood of having chronic sleep problems in adolescents. A sample of n = 131 adolescents (M = 14.31 years, SD = 1.84) completed the Sleep Disturbance Scale for Children and the Questionnaire to Assess Resources for Children and Adolescents at two measurement points about 8 months apart. Binomial logistic regressions controlling for age and sex revealed that higher levels of personal and social resources were associated with a lower likelihood of having chronic sleep problems. Especially optimism and school integration were associated with not experiencing chronic sleep problems. For the first time, this study highlighted multiple resources and their health-promoting role in adolescent sleep. Both personal and social resources seem to be relevant for preventing adolescents from chronic sleep problems. Prevention and intervention programs for sleep disorders in teenagers should especially promote optimism and school integration. [ABSTRACT FROM AUTHOR]

This commentary provides some reflections on the studies included in the special issue and their findings, focusing on three topics in particular. First, moral disengagement as a factor associated with bias-based discrimination, harassment, and bullying is discussed. Second, the negative effects of bias-based victimization and factors that might mitigate them are contemplated, with special attention to peer defending. Finally, some implications for prevention and intervention are considered. [ABSTRACT FROM AUTHOR]

Since 2015, UNESCO has developed a variety of programmes for preventing violent extremism through education (PVE-E), under the framework of Global Citizenship Education and Target 4.7 of Agenda 2030. There have been formal board decisions to promote PVE-E, regional and international conferences and three key publications: a Teacher's Guide (2016), a Guide for Policy-makers (2017), and a Youth-Led Guide (2017 and 2018). Through a discourse analysis of these key documents and a critical engagement with the institutional politics of UNESCO, the paper delineates the discursive constructs of PVE-E that are mobilised and sheds light on the under-researched politics of production that affect the nature of these texts. Taking a comparative perspective, the paper shows how PVE-E is represented within and between these different texts, exposes the normative values and ideological assumptions underpinning these representations and argues that we are ultimately witnessing a declining legitimacy of UNESCO's normative power. [ABSTRACT FROM AUTHOR]

To develop harmful sexual behavior (HSB) early intervention strategies it is essential to understand how children come to engage in HSB. Through the lens of a pathways theory, this paper reports a scoping review of the literature in answer to the research question: What are the pathways to HSB onset for children and young people? Eight bibliographic databases were searched over the time period January 2000 to May 2022 using the following terms (and derivatives): harmful sexual behavior AND children and young people AND pathways. Forty-three papers were included and 10 pathways to onset identified through synthesis: Child sexual abuse victimization; Physical and emotional abuse; Living with domestic and family violence; Disrupted attachments; Sexual arousal; "Antisociality;" Pornography use; Inadequate sexual boundaries; Sexual attraction to children; and Hypermasculinity. The pathways are discussed in terms of opportunities for early intervention. [ABSTRACT FROM AUTHOR]

Given the significant consequences of child sexual abuse (CSA), researchers and policymakers have made considerable efforts to develop and implement prevention strategies. However, these efforts are rarely informed by those who arguably have the most expertise on the matter – survivors of CSA. The present study examined recommendations for the prevention of CSA – from the child, parent, and community level – from a sample of 52 adults who experienced CSA. Overall, the results showed that prevention is a multi-level endeavor that should target children, parents and caregivers, and the community at large. [ABSTRACT FROM AUTHOR]