1. Ph-activated nano-amorphous calcium phosphate-based cement to reduce dental enamel demineralization.
- Author
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Melo, Mary A. S., Weir, Michael D., Passos, Vanara F., Powers, Michael, and Xu, Hockin H. K.
- Subjects
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DENTAL enamel , *CALCIUM phosphate , *DENTAL cements , *TOOTH demineralization , *ORTHODONTICS - Abstract
Enamel demineralization is destructive, esthetically compromised, and costly complications for orthodontic patients. Nano-sized amorphous calcium phosphate (NACP) has been explored to address this challenge. The 20% NACP-loaded ortho-cement notably exhibited favorable behavior on reducing demineralization of enamel around brackets in a caries model designed to simulate the carious attack. The 20% NACP-loaded ortho-cement markedly promotes higher calcium and phosphate release at a low pH, and the mineral loss was almost two fold lower and carious lesion depth decreased the by 1/3. This novel approach is promising co-adjuvant route for prevention of dental caries dissemination in millions of patients under orthodontic treatment. [ABSTRACT FROM PUBLISHER]
- Published
- 2017
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