Search

Your search keyword '"Yakushiji, Fumika"' showing total 1 results
Start Over Author "Yakushiji, Fumika" Publisher taylor & francis ltd
Sorry, I don't understand your search. ×
1 results on '"Yakushiji, Fumika"'

1. Synthesis and biological evaluation of a MraY selective analogue of tunicamycins.

Author

Yamamoto, Kazuki, Sato, Toyotaka, Hikiji, Yuta, Katsuyama, Akira, Matsumaru, Takanori, Yakushiji, Fumika, Yokota, Shin-Ichi, and Ichikawa, Satoshi

Subjects
BIOSYNTHESIS, NATURAL products, ORGANIC chemistry
Abstract

Tunicamycins, which are nucleoside natural products, inhibit both bacterial phospho-N-acetylmuraminic acid (MurNAc)-pentapeptide translocase (MraY) and human UDP-N-acetylglucosamine (GlcNAc): polyprenol phosphate translocase (GPT). The improved synthesis and detailed biological evaluation of an MraY-selective inhibitor, 2, where the GlcNAc moiety was modified to a MurNAc amide, has been described. [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results