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Using potassium iodide as a catalyst andm-chloroperbenzoic acid as an oxidant, an efficient catalytic procedure has been developed for the azidoselenenylation of alkenes with sodium azide and diselenides, and a series of corresponding β-azidoselenides, most of which are new compounds, have been prepared in moderate to good yields under mild reaction conditions. This in situ generation of the electrophilic selenenylating reagents with addition to alkenes is a stereospecificantiaddition, which occurs with a Markovnikov orientation. [ABSTRACT FROM AUTHOR]

A convenient procedure is developed for the preparation ofN-sulfonylbenzotriazoles from sodium sulfinates, benzotriazoles, and sodium bromide in the present ofm-chloroperbenzoic acid as oxidant. This radical sulfonylation proceeds efficiently at room temperature under neutral conditions, affording the correspondingN-sulfonylbenzotriazoles in moderate to good yields in a short time. [ABSTRACT FROM AUTHOR]

A heterogeneous platinum catalyst with tridentate pyridine Schiff base ligands supported on silica gel is reported. The catalyst was fully characterized via FTIR, solid-state 13C NMR spectroscopy, X-ray photoelectron spectroscopy (XPS), N2 adsorption/desorption analysis, X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The catalyst showed potential application in mediating hydrosilylation reactions between olefins and hydrosilanes, and it can be reused for at least five cycles. [ABSTRACT FROM AUTHOR]

Background: Studies on the relationship between thyroid function and non-alcoholic fatty liver disease (NAFLD) among euthyroid subjects have produced conflicting results.Objectives: The aim of this study was to investigate the association between thyroid function and the presence of NAFLD in a large-sample middle-aged euthyroid subjects.Methods: A total of 2576 euthyroid subjects who underwent health check-up were included. NAFLD was diagnosed by hepatic ultrasonography. Conventional risk factors for NAFLD were assessed as well as serum levels of TSH, FT3 and FT4.Results: Levels of FT3 were significantly higher in NAFLD group (5.12 ± 0.58 versus 4.84 ± 0.58 pmol/L, adjustedp = 0.000) than non-NAFLD group, while levels of TSH and FT4 were comparable between NAFLD and non-NAFLD groups (TSH: 2.13 ± 0.90 versus 2.20 ± 0.93 mIU/L, adjustedp = 0.190; FT4: 16.41 ± 2.04 versus 16.18 ± 2.06 pmol/L, adjustedp = 0.146, respectively). Levels of FT3 were positively correlated with components of metabolic syndrome. Multivariate logistic regression analysis revealed that high level of FT3 was an independent predictor for NAFLD (odds ratio: 1.253,p = 0.040). The relationship between FT4 and NAFLD in women was different according to menopausal status, with negative association in pre-menopausal women (OR: 0.777, 95% CI: 0.617–0.979,p = 0.032) and null association in post-menopausal women (OR: 1.037, 95% CI: 0.841–1.277,p = 0.736).Conclusions: Our findings suggested that high levels of FT3 were significantly associated with NAFLD among middle-aged euthyroid subjects independently of known metabolic risk factors. A negative correlation of serum FT4 level with NAFLD was only observed in pre-menopausal women. [ABSTRACT FROM AUTHOR]