1. Impact of CT-apelin and NT-proBNP on identifying non-responders to cardiac resynchronization therapy
- Author
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Annamaria Kosztin, Valentina Kutyifa, Gabor Foldes, Béla Merkely, Eszter M. Végh, Daniel Aradi, István Szokodi, Attila Kovács, Klaudia Vivien Nagy, Gábor Széplaki, László Gellér, Dávid Becker, and Eva Forizs
- Subjects
Male ,Health, Toxicology and Mutagenesis ,medicine.medical_treatment ,Clinical Biochemistry ,MADIT-CRT ,030204 cardiovascular system & hematology ,Logistic regression ,Toxicology ,Biochemistry ,Cardiac Resynchronization Therapy ,0302 clinical medicine ,renal disease ,Natriuretic Peptide, Brain ,Clinical endpoint ,Medicine ,030212 general & internal medicine ,IN-VIVO ,Ejection fraction ,DYSSYNCHRONY ,Middle Aged ,Brain natriuretic peptide ,Cardiovascular disease ,CHRONIC HEART-FAILURE ,Apelin ,Treatment Outcome ,apelin ,ORPHAN RECEPTOR APJ ,BRAIN NATRIURETIC PEPTIDE ,Predictive value of tests ,Cardiology ,Biomarker (medicine) ,Intercellular Signaling Peptides and Proteins ,Regression Analysis ,Female ,Life Sciences & Biomedicine ,hormones, hormone substitutes, and hormone antagonists ,DEFIBRILLATOR IMPLANTATION TRIAL ,medicine.medical_specialty ,Cardiac resynchronization therapy ,1002 Environmental Biotechnology ,03 medical and health sciences ,Predictive Value of Tests ,Internal medicine ,Humans ,cardiovascular diseases ,Aged ,Science & Technology ,business.industry ,ENDOGENOUS INOTROPE APELIN ,CRT responder ,CONTRACTILITY ,Peptide Fragments ,Biotechnology & Applied Microbiology ,NT-proBNP ,VAL-HEFT ,business ,Biomarkers - Abstract
Context: Assessment of response to cardiac resynchronization therapy (CRT) is essential.Objective: To assess the predictive value of CT-apelin together with NT-proBNP in patients undergoing CRT.Methods: Serum CT-apelin and NT-proBNP were measured by ELISA before, and six months after CRT. Primary endpoint was non-response (
- Published
- 2016