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Copyright of Psycho-Oncologie is the property of Tech Science Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Testicular tumours are the most common form of cancer in young men. Since the 1970s, metastatic germ cell tumours have become the curable cancer paradigm through the use of cisplatin-based chemotherapy and surgical removal of the residual mass. The prognosis for patients is defined using the International IGCCCG classification, which enables the appropriate amount of chemotherapy therapy to be administered in order to achieve recovery. In the most serious forms, early adaptation of the chemotherapy regimen based on the decreasing levels of serum markers has been shown to be effective. Despite these treatments, approximately 20% of patients relapse and require a second line treatment, either at a standard dose or at an intensified level with a stem cell transplant. Follow-up of patients in complete remission is important, not only for the early detection of any relapses, but also to screen for testicular cancer in the other side, associated with the potential desire to father a child, and favours the best possible social rehabilitation of the patient. [ABSTRACT FROM AUTHOR]

Copyright of Psycho-Oncologie is the property of Tech Science Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Psycho-Oncologie is the property of Tech Science Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Psycho-Oncologie is the property of Tech Science Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In all developing countries, childhood cancer care runs into a number of common hurdles: poverty, poorly functioning healthcare systems, incompetence, and inequalities. In Africa, with its complex geopolitical situation, all such problems are compounded. The Groupe Franco-Africain d’Oncologie Pédiatrique provides onsite cancer care to African children. Its activities include the training of physicians and nurses, clinical trials of treatment protocols (Burkitt’s lymphoma and Wilms’ tumor), provision of medicines, and coverage of medical examination fees in the areas where the problems exist. After five years of study and 1000 cases, the preliminary findings are promising: it is possible to treat childhood cancer in Africa. This work is ongoing. [ABSTRACT FROM AUTHOR]

After more than a decade of treatment of chronic myeloid leukemia (CML) patients with the BCR-ABL tyrosine-kinase inhibitor imatinib, and despite the impressive results obtained with the use of this targeted therapy, the major question of how to cure CML remains unresolved. The next step for the future will be to address this key issue. CML is a model disease with a defined oncogenic driver, the BCR-ABL oncoprotein. The fact that the majority of CML patients who respond very well to BCR-ABL targeted therapy show evidence of molecular recurrence upon treatment discontinuation focuses the attention on the need for further research on the persistence of leukemic stem cells. The challenge now is to understand why, after stopping the treatment, leukemia recurs in some patients but not in others. Wining this battle is a challenge and will certainly benefit the treatment and management of other leukemias and solid tumors and will validate this new topic. [ABSTRACT FROM AUTHOR]

xis 5 of the 2009-2013 Cancer Plan: 'Living with the disease and after it.' This 'provocative' heading emphasises a metaphor of life and of the passage of time in association with the word cancer, which more often carries images of cessation, termination and death. [ABSTRACT FROM AUTHOR]