Hironori, Akiyama, Ken, Yoshida, Tadashi, Takenaka, Tadayuki, Kotsuma, Koji, Masui, Hajime, Monzen, Iori, Sumida, Yutaka, Tsujimoto, Mamoru, Miyao, Hiroki, Okumura, Taiju, Shimbo, Hideki, Takegawa, Naoya, Murakami, Koji, Inaba, Tairo, Kashihara, Zoltán, Takácsi-Nagy, Nikolaos, Tselis, Hideya, Yamazaki, Eiichi, Tanaka, Keiji, Nihei, and Yoshiko, Ariji
The purpose of this study was to evaluate the effect of a lead block for alveolar bone protection in image-guided high-dose-rate interstitial brachytherapy for tongue cancer.We treated 6 patients and delivered 5,400 cGy in 9 fractions using a lead block. Effects of lead block (median thickness, 4 mm) on dose attenuation by distance were visually examined using TG-43 formalism-based dose distribution curves to determine whether or not the area with the highest dose is located in the alveolar bone, where there is a high-risk of infection. Dose re-calculations were performed using TG-186 formalism with advanced collapsed cone engine (ACE) for inhomogeneity correction set to cortical bone density for the whole mandible and alveolar bone, water density for clinical target volume (CTV), air density for outside body and lead density, and silastic density for lead block and its' silicon replica, respectively.The highest dose was detected outside the alveolar bone in five of the six cases. For dose-volume histogram analysis, median minimum doses delivered per fraction to the 0.1 cmThe results suggested that using a lead block for alveolar bone protection with a thickness of about 4 mm, can shift the highest dose area to non-alveolar regions. In addition, it reduced D0.1cm