66 results on '"Johnson, Aaron"'
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2. Time Course scRNAseq Analysis Reveals Mechanisms of Impaired Lung Recovery Post Influenza Infection during Aging: Zooming into Macrophages
3. Circulating cell-free DNA directly inhibits T cell function and contributes to peripheral immunosuppression in experimental GBM
4. Antigen-specific reactivation of brain tissue resident memory CD8 T cells directly induces severe neuroinflammation and blood-brain-barrier disruption
5. Cell-specific MHC class I deletion on CD11c+ APCs abrogates CD8 T Cell infiltration into the brain
6. Dissecting the role of H-2D bclass I molecule in the development of brain atrophy during Theiler’s murine encephalomyelitis virus (TMEV) infection
7. Dissecting the role of H-2Db class I molecule in the development of brain atrophy during Theiler’s murine encephalomyelitis virus (TMEV) infection
8. Evaluation of tumor derived Serpina3n in experimental glioblastoma
9. Respiratory humoral and cellular immune responses following COVID-19 mRNA vaccination
10. Induction of blood brain barrier disruption through reactivation of virus antigen specific brain resident memory T cells
11. H-2Kb and H-2Db class I molecules on cerebral endothelium differentially modulate CD8 T cells dynamics and pathological outcomes in experimental cerebral malaria
12. Time course scRNAseq analysis on host mucosal immune responses to influenza virus infection during aging
13. Heightened levels of circulating cell-free DNA predict aggressive onset of experimental glioblastoma
14. Hv1 proton channels control myeloid landscape and promote glioma progression
15. Combination of αPD-1 and extended half-life IL-2 is effective against the GL261 glioma and uniquely reverses GBM-associated immunosuppression
16. Antigen presentation by CNS-resident microglia and macrophages regulates CD8 T cell infiltration of the brain during central nervous system (CNS) infection
17. Concurrent microglial activation in CD8 T cell-mediated CNS vasculature permeability during Theiler’s virus infection
18. Ag-dependent Engagement of CD8+ T Cells with H-2Kb on Brain Endothelium Required for CD8+ T Cell entry and Cerebral Manifestation of Malaria
19. αPD-1 and extended half-life IL-2 combination therapy clears established GL261 gliomas in an MHC class I independent fashion
20. Mapping the thymic neuronal connectome using rabies virus retrograde and anterograde tracers
21. Conditional Silencing of H-2Db Class I Molecule Expression Modulates the Protective and Pathogenic Kinetics of Virus-Antigen–Specific CD8 T Cell Responses during Theiler's Virus Infection
22. Discordant requirements for CD11c+ APCs in priming CD8 T cell responses against H-2Kb versus H-2Db restricted TMEV-associated peptides
23. Combination immunotherapy of αPD-1 and extended half-life IL-2 clears established GL261 gliomas in an MHC class I independent fashion
24. A generalized pathway of immunocompromise following central nervous system insult: the release of large immunosuppressive molecules and thymic involution
25. Concurrent microglial activation in CD8 T cell-mediated CNS vascular permeability during Theiler’s virus infection
26. Naive brain harbors resident memory T cells that respond to neurological insults prior to infiltration of antigen specific T cells
27. Antigen presentation by CNS-resident microglia and macrophages is required for antiviral CD8 T cell responses in the brain following CNS viral challenge
28. Conditional ablation of H-2Kb and H-2Db on discrete APC subsets modulate outcomes in experimental cerebral malaria
29. Activation of microglia in CD8 T cell-initiated blood-brain barrier disruption induced during Theiler’s virus infection
30. Upregulation of Neuronal VEGF in Experimental Cerebral Malaria Coincides with Disease Severity Biomarkers in Humans: A Novel Mechanism of Pathophysiology
31. Rapid activation of brain resident memory T cells following neurological insults
32. Brain-Thymus communication is a novel immunosuppressive feature of neurological insults
33. Microglial antigen presentation is required for antigen specific CD8 T cell infiltration to the brain parenchyma following CNS viral challenge
34. Isolation and analysis of plasma-derived exosomes in patients with glioblastoma
35. MHC class I expression by microglia is required for generating a complete antigen-specific CD8 T cell response in the CNS
36. Dendritic cell expressed H-2Db is required for generating antiviral CD8+ T cell responses and blood brain barrier disruption during Theiler’s virus infection
37. Brain-Thymus communication as a novel immunosuppressive mechanism in the GL261 model of Glioblastoma
38. Non-cellular mechanism of peripheral immunosuppression as a novel feature in experimental glioblastoma
39. Virus antigen-specific CD8 T cells contribute to brain atrophy during Theiler’s murine encephalomyelitis virus (TMEV) infection of the CNS.
40. Defining the Impact of Antigen Presentation by Dendritic Cells and Macrophages in CNS Cancer Using a Novel H-2Kb MHC Class I Conditional Knockout Mouse
41. IL-15 complex-stimulated NK cells protect mice from cerebral malaria
42. Conditional silencing of the H-2Db class I molecule on CD11c+ Dendritic Cells inhibits the generation of antiviral CD8 T Cells during acute Theiler’s Murine Encephalomyelitis Virus (TMEV) infection in the CNS
43. CD8 T cells initiate blood-brain barrier disruption during experimental cerebral malaria through non-cytotoxic alterations to endothelial cells
44. Modulatory effect of perforin gene dosage during pathogen associatated blood brain barrier (BBB) disruption
45. Immunomodulation mediated by anti-angiogenic therapy improves viral vaccination against GL261 glioma tumors.
46. Transgenic expression of H-2Db class I molecules influences the development of brain atrophy during Picornavirus infection
47. CD8 T cell mediated blood-brain barrier disruption promotes vascular leakage and edema in vital brain regions during experimental cerebral malaria
48. Superior isolation of antigen-specific brain infiltrating T cells using manual homogenization technique
49. Alpha-beta T cell positive selection is enhanced by CD3-delta via a quantitative developmental signaling mechanism
50. Defining the role of CD4 T cells during acute Theiler's murine encephalomyelitis virus infection (VIR1P.1141)
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