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Your search keyword '"Tomoki Nishimura"' showing total 5 results
Start Over Author "Tomoki Nishimura" Publisher the chemical society of japan
5 results on '"Tomoki Nishimura"'

1. Synthesis of a Highly Hydrophobic Cationic Lipid and Structural and Thermodynamic Studies for Interaction with DNA

Author

John S. Fossey, Tomoki Nishimura, Tony D. James, Steven D. Bull, Hiroyasu Masunaga, Andrew M. Kelley, Magdalena E. Powell, Takeshi Cho, Kazuo Sakurai, and Isamu Akiba

Subjects
chemistry.chemical_compound, Chemistry, Stereochemistry, viruses, Reagent, fungi, Cationic polymerization, Supramolecular chemistry, food and beverages, lipids (amino acids, peptides, and proteins), General Chemistry, Dna viral, DNA
Abstract

Synthetic DNA-transfection reagents can overcome safety issues raised by use of viral DNA vectors. One of these candidates is a cationic lipid that can form a supramolecular complex with DNA. We ha...

Published
2010
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2. Thermodynamics of Lipoplex Formation: Relationship between the Lipid Alkyl Tail Length and Thermodynamic Functions

Author

Tomoki Nishimura, Shota Fujii, and Kazuo Sakurai

Subjects
Quaternary amine, chemistry.chemical_classification, Chemistry, Polymer chemistry, technology, industry, and agriculture, Organic chemistry, lipids (amino acids, peptides, and proteins), General Chemistry, Dna complex, Alkyl, Lipoplex
Abstract

The formation of a cationic-lipid/DNA complex (lipoplex), where the lipids that have a quaternary amine headgroup and alkyl tails of various lengths are newly synthesized, was investigated by use o...

Published
2012
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3. Quaternary-ammonium-bearing Aromatic Surfactants: Effect of the Alkyl Chain Positions on Their Micelle and DNA-complex Structures

Author

Yusuke Sanada, Tomoki Nishimura, Shota Fujii, Shinichi Mochizuki, Takuma Matsuo, Yumi Kamikawa, and Kazuo Sakurai

Subjects
chemistry.chemical_classification, chemistry.chemical_compound, Chain (algebraic topology), Chemistry, Polymer chemistry, technology, industry, and agriculture, Organic chemistry, lipids (amino acids, peptides, and proteins), Ammonium, General Chemistry, Dna complex, Micelle, Alkyl
Abstract

The isomeric effect was investigated for a newly synthesized series of quaternary aromatic ammoniums with alkyl chains of different substitution position. Their micellar and DNA-complex structures ...

Published
2011
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4. Cation-specific Transition from Vesicle to Lamella for an Aromatic Diamine Lipid in Aqueous Solutions

Author

Tomoki Nishimura, Isamu Akiba, Hiroyasu Masunaga, Kazuo Sakurai, and Hiroki Ogawa

Subjects
inorganic chemicals, Aqueous solution, Chemistry, Scattering, Aromatic diamine, Vesicle, Polymer chemistry, Organic chemistry, General Chemistry, Calorimetry, Lamella (cell biology)
Abstract

Addition of Cu2+ or Pd2+ into a novel aromatic diamine lipid in water induced vesicle–lamella transition. Combining scattering and calorimetry revealed that the metals first coordinated on the vesi...

Published
2010
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5. DNA Conformational Switching by Use of an Intercalator and Its Receptor

Author

Kazuo Sakurai, Tomoki Nishimura, Yoichi Takeda, and Naohiko Shimada

Subjects
chemistry.chemical_compound, Chemistry, Stereochemistry, Intercalation (chemistry), Tilorone, medicine, General Chemistry, Receptor, DNA, medicine.drug
Abstract

DNA conformational switching between B and Z forms was controlled with tilorone (intercalator) and sulfocalix[8]arene (C8AS, receptor for tilorone). When tilorone was added to the Z-DNA that had be...

Published
2007
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