1. The dystrophin-associated protein complex
- Author
-
Jeffrey Ehmsen, Kay E. Davies, and Ellen Poon
- Subjects
musculoskeletal diseases ,congenital, hereditary, and neonatal diseases and abnormalities ,Duchenne muscular dystrophy ,Muscle Proteins ,medicine.disease_cause ,Dystrophin-associated protein complex ,Utrophin ,medicine ,Animals ,Humans ,Muscle, Skeletal ,Cytoskeleton ,Genetics ,Mutation ,biology ,Cardiac muscle ,Cell Biology ,musculoskeletal system ,medicine.disease ,Extracellular Matrix ,Muscular Dystrophy, Duchenne ,medicine.anatomical_structure ,biology.protein ,Dystrophin ,ITGA7 - Abstract
The lethal muscle-wasting disorder, Duchenne muscular dystrophy, is caused by mutations or deletions in the dystrophin gene. In skeletal and cardiac muscle, dystrophin associates with various proteins to form the dystrophin-associated protein complex (DAPC). The DAPC is thought to play a structural
- Published
- 2002
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