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Your search keyword '"Shoko Yamazaki"' showing total 6 results
Start Over Author "Shoko Yamazaki" Publisher the japan institute of heterocyclic chemistry
6 results on '"Shoko Yamazaki"'

3. A Lewis-Acid Catalyzed Synthesis of Substituted Oxindole Derivatives

Author

Shoko Yamazaki, Machiko Yamamoto, and Satoshi Morikawa

Subjects
Pharmacology, chemistry.chemical_classification, Organic Chemistry, Regioselectivity, chemistry.chemical_element, Medicinal chemistry, Nitrogen, Analytical Chemistry, Catalysis, chemistry.chemical_compound, chemistry, Oxindole, Lewis acids and bases, Selectivity, Friedel–Crafts reaction, Alkyl
Abstract

Lewis acid-catalyzed cyclization of various 2-(N-arylcarbamoyl)-methylenemalonates to give nitrogen-containing benzo-annelated heterocycles was investigated in terms of selectivity. Reaction of substrates with various alkyl groups on nitrogen proceeded to give oxindole derivatives. Cyclization reaction of diester-amides of MeO and halogen-substituted anilines in the presence of catalytic Lewis acid (ZnCl 2 , SnCl 4 , AlCl 3 , Zn(OTf) 2 , Sc(OTf) 3 , etc.) gave oxindoles in high yields. Interesting regioselectivity was observed for metahalogen substrates. Dimethoxyisoquinoline analogs were also obtained by this reaction using a catalytic Lewis acid.

Published
2006
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4. The Homothiopyrylium Ions

Author

Shoko Yamazaki, Ichiro Murata, Kagetoshi Yamamoto, and Atsuhiro Matsukawa

Subjects
Pharmacology, Chemistry, Organic Chemistry, Inorganic chemistry, Analytical Chemistry, Ion
Published
1984
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