1. Effects of induced endometritis on uterine blood flow in cows as evaluated by transrectal Doppler sonography
- Author
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Eleonora Iacono, Heinrich Bollwein, Barbara Merlo, Gaetano Mari, Sabine Merbach, Heinz-Adolf Schoon, Letizia Debertolis, Debertolis, L, Mari, G, Merlo, B, Merbach, S, Schoon, Ha, Iacono, E, Bollwein, H., University of Zurich, and Merlo, Barbara
- Subjects
medicine.medical_specialty ,endometritis ,3400 General Veterinary ,Uterus ,cow ,Cattle Diseases ,Endometrium ,Andrology ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,medicine.artery ,Internal medicine ,Biopsy ,Medicine ,Animals ,Ultrasonography, Doppler, Color ,Uterine artery ,color Doppler sonography ,Estrous cycle ,030219 obstetrics & reproductive medicine ,General Veterinary ,medicine.diagnostic_test ,630 Agriculture ,business.industry ,0402 animal and dairy science ,04 agricultural and veterinary sciences ,Blood flow ,medicine.disease ,040201 dairy & animal science ,10187 Department of Farm Animals ,Uterine Artery ,medicine.anatomical_structure ,Endocrinology ,Policresulen ,chemistry ,uterine blood flow ,570 Life sciences ,biology ,Original Article ,Cattle ,Female ,Endometritis ,business ,endometriti - Abstract
This study was conducted to evaluate the effects of induced endometritis on uterine blood flow in cows. Transrectal Doppler sonography was performed on uterine arteries of six cyclic cows before and for 4 days after inducing acute endometritis by intrauterine infusion of 720 mg of policresulen, and for 4 days of the following estrous cycle. Time-averaged maximum velocity (TAMV) increased (p < 0.001) and pulsatility index (PI) decreased (p < 0.0001) within 1 h of policresulen administration, and did not change (p > 0.05) in the next 4 days of the same cycle. TAMV and PI values in the subsequent cycle did not differ (p > 0.05) from the values measured before infusion and showed no changes (p > 0.05) within the cycle. Blood flow parameters were not related (p > 0.05) to plasma concentrations of progesterone and estrogen. All cows showed an acute endometritis determined by histopathological findings of biopsy samples taken 1 day after infusion and fibrotic endometrial alterations detected in the subsequent cycle. No relationships were observed between fibrotic changes of the endometrium and uterine blood flow during either cycle. In conclusion, acute inflammation is accompanied by a rise in uterine blood flow, but fibrotic alterations do not seem to be related to Doppler sonographic findings.
- Published
- 2016