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Your search keyword '"Christoph Rosenbohm"' showing total 1 results
Start Over Author "Christoph Rosenbohm" Publisher the royal society of chemistry
1 results on '"Christoph Rosenbohm"'

1. Locked Nucleic Acid: Properties and Therapeutic Aspects

Author

Ellen Marie Straarup, Christoph Rosenbohm, Bo Hansen, Troels Koch, Sakari Kauppinen, and Henrik Frydenlund Hansen

Subjects
Messenger RNA, Biochemistry, Oligonucleotide, media_common.quotation_subject, Simplicity, Biology, Locked nucleic acid, Gene, Psychological repression, media_common
Abstract

In 1978 Zamecnik and Stephenson1 showed for the first time that messenger RNA (mRNA) repression could be achieved by single-stranded oligonucleotides (ONs). This mechanistic approach for gene inhibition was later called the antisense (AS) principle. The simplicity of this new principle captivated ma...

Published
2008
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