1. Qumai Total Flavonoids Induced Diabetic Mice Model of Streptozotocin
- Author
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Na Jiang, Bo Lin Cheng, Ming San Miao, and Mei Qiong Jiang
- Subjects
medicine.medical_specialty ,biology ,Glycogen ,Therapeutic effect ,Dianthus superbus ,General Medicine ,biology.organism_classification ,medicine.disease ,Streptozotocin ,chemistry.chemical_compound ,medicine.anatomical_structure ,Endocrinology ,chemistry ,Diabetes mellitus ,Internal medicine ,medicine ,Urea ,Pancreas ,Blood Glucose Measurement ,medicine.drug - Abstract
Purpose: Research Qumai total flavonoids induced diabetic mice model of streptozotocin. Methods: 12 h after fasting groups of mice, Tail vein injection of citrate buffer chain urea with cephalosporins solution (80mg/kg,0.02ml/10g), To 1 times a day. In dosing 10, 20, 30 days tail blood glucose measurement value. On the 30th day fasting 12 h after the last for 1 h, Some blood, Measuring blood glucose、Glycosylation of serum protein, Serum insulin、Insulin resistance value;After the death in mice,Take the liver glycogen original value;Take the pancreas, and kidneys,10% formalin fixed liquid, As a pathological. Results: Compared with model group、blank group, each dose of dianthus superbus flavonoids to chain urea with cephalosporins cause diabetes in mice model can significantly improve the experiment indexes. Conclusion: Dianthus superbus flavonoids to chain urea with cephalosporins caused diabetes in mice model has good therapeutic effect.
- Published
- 2014
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