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Background: Diabetic foot patients are more likely to have mental disorders such as anxiety and depression, which can have a significant impact on emotional and psychological performance compared to diabetics who have not experienced foot complications. Aims of the study: The study aims to assess the level of depression among diabetic foot patients at Al-Najaf Al-Ashraf Teaching Hospitals and to find out relationships between depression among diabetic foot patients and their demographic characteristics. Methodology: a study conducted by a descriptive design cross-sectional, this study carried out for a period of 10th October, 2020 to 1st June, 2021. Anon-probability (accidental) sample including 120 patients who have a diabetic foot which was selected of Al-Sadder teaching hospital and Al-Furat teaching hospital in Al-Najaf Al-Ashraf Governorate, the researcher is using the Hospital Anxiety and Depression Scale to assess the level of anxiety and depression. Results: The result showed (36.6%) of the study participant have moderate depression. Contingency correlation analysis showed that depression is a significant correlation with the number of hospital admission, duration of current admission, and previous amputation, in addition, significantly correlated with age, economic status, having other chronic diseases. Conclusion: The researcher concludes that the level of anxiety and depression among diabetic foot patients has moderate. Recommendations: The study has recommended when dealing with diabetic foot patients, the health care workers devote their time to examining mental health. Also, predict the negative effects of social and psychological effects on mental and physical health