1. THE EFFECT OF A TOPICAL TREATMENT BASED ON SAMBUCI FLOS EXTRACT IN EXPERIMENTAL THERMAL THIRD DEGREE SKIN BURNS.
- Author
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Mogoşanu, George Dan, Popescu, Florina Carmen, Busuioc, Cristina Jana, Pop, Oltin Tiberiu, Pârvănescu, Horia, Lascăr, Ioan, and Mogoantă, Laurenţiu
- Subjects
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ETHNOPHARMACOLOGY , *PHARMACOPOEIAS , *LABORATORY rats , *SKIN diseases , *SULFADIAZINE - Abstract
In the European ethnopharmacology, elder flowers are used external in poultices for the treatment of burns and blisters. Sambuci flos tincture was prepared and physico-chemically analyzed according to Romanian Pharmacopoeia. The soft extract, obtained from tincture, was embedded in an ointment base of cold cream type, prepared according to United States Pharmacopoeia. The study was performed on three groups of adult male Wistar rats, each of ten animals, kept under standard conditions, both before and after the burns. Skin burns from the dorsal region were treated daily as follows: cold cream with 10% Sambuci flos extract (SFE) for the first group; 1% silver sulfadiazine cream (SDA) for the second group; the third group, considered as control, received the cold cream base (CCB). The favorable evolution of burnt skin wounds in the SFE group, compared to SDA and CCB groups, is mainly due to the astringent, anti-inflammatory, antiseptic and cicatrizing action of the natural product. [ABSTRACT FROM AUTHOR]
- Published
- 2011