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16 results on '"Goudsmit R"'

2. [Primary treatment of acute promyelocytic leukemia using all-trans-retinoic acid].

Author

Leeksma OC, van Oers MH, van der Schoot CE, Goudsmit R, and von dem Borne AE

Subjects
Aged, Blood Transfusion, Combined Modality Therapy, Female, Humans, Leukemia, Promyelocytic, Acute therapy, Platelet Transfusion, Remission Induction, Antineoplastic Agents therapeutic use, Leukemia, Promyelocytic, Acute drug therapy, Tretinoin therapeutic use
Abstract

We describe the medical history of a 68-year-old woman with acute promyelocytic leukaemia. As primary treatment she received all-trans retinoic acid. For the major part this treatment could be given on an outpatient basis. After 60 days there was a complete remission of the leukaemia with disappearance of the characteristic cytogenetic abnormality t(15;17)(q22;q21).

Published
1993

4. [Long-term treatment of patients with transfusion hemosiderosis using oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1)].

Author

Goudsmit R

Subjects
Adolescent, Adult, Aged, Aged, 80 and over, Deferiprone, Female, Ferritins blood, Hemosiderosis etiology, Humans, Iron urine, Long-Term Care, Male, Pyridones adverse effects, Pyridones chemistry, Hemosiderosis drug therapy, Iron Chelating Agents therapeutic use, Pyridones therapeutic use, Transfusion Reaction
Abstract

A new oral iron chelator, L1, was given for 14 to 16 months to four patients with transfusion haemosiderosis. These patients could no longer be treated with deferoxamine because of allergic reactions or psychological problems. Serum ferritin values at the start of the treatment ranged from 2220 to 4530 microgram/l. L1 was given in a total daily dose of 3 g, at first in a single dose, later 3 times 1 g daily. The 24-hour urinary excretion of iron varied greatly from day to day. The mean urinary iron excretion of the four patients ranged from 19.3 to 45.7 mg/day. In two patients an important decrease of ferritin was found. These patients had been given no more or only sporadic transfusions. In one patient transient agranulocytosis was seen which was probably not caused by L1.

Published
1991

5. [Prophylactic iron in pregnant women?].

Author

Goudsmit R

Subjects
Female, Humans, Pregnancy, Anemia, Hypochromic prevention & control, Iron therapeutic use, Pregnancy Complications, Hematologic prevention & control
Published
1975

6. [Current approach to the management of patients with hemato-oncologic diseases].

Author

Goudsmit R, van der Lelie J, and Thomas LL

Subjects
Adult, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Combined Modality Therapy, Female, Humans, Male, Recombinant Proteins therapeutic use, Interferon Type I therapeutic use, Leukemia, Hairy Cell therapy, Leukemia, Myeloid therapy, Leukemia, Myeloid, Acute therapy
Published
1987

8. [DIAGNOSIS OF ANEMIA USING RADIOACTIVE ISOTOPES].

Author

GOUDSMIT R

Subjects
Humans, Anemia, Chromium Isotopes, Diagnosis, Differential, Erythrocytes, Hematinics, Iron Isotopes, Phosphorus Isotopes, Radioisotopes, Vitamin B 12
Published
1964

9. [Use of radiochromium].

Author

GOUDSMIT R and KRIJNEN HW

Subjects
Chromium, Chromium Radioisotopes, Erythrocytes
Published
1957

13. [TREATMENT OF IRON LOADING WITH DESFERRIOXAMINE].

Author

DE VRIES SI, GOUDSMIT R, SCHRETLEN ED, and VAN MUNSTERP

Subjects
Adolescent, Child, Humans, Anemia, Anemia, Hemolytic, Anemia, Macrocytic, Deferoxamine, Geriatrics, Hemosiderosis, Hydroxamic Acids, Iron
Published
1963

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