1. Determination of the incidence of cardiovascular composite events in Patients with Obstructive Sleep Apnea: A 3-year follow-up
- Author
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Sayed Mohammad Amin Sayedain, Saedeh Bahrani, Asieh Mansouri, Jamshid Najafian, Mohaddeseh Behjati, Shahin Shirani, Babak Amra, Mohammad Emami Ardestani, Maryam Khosravi, and Alireza Khosravi
- Subjects
sleep apnea ,cardiovascular composite events ,cerebrovascular diseases ,risk factors ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Background: The occurrence of obstructive sleep apnea (OSA) and its health-related issues, especially cardiovascular diseases (CVD), are increasing in developing countries. With a 3-year follow-up study, the present study aimed to determine the incidence of cardiovascular events in patients with OSA in an Iranian population.Methods: In this prospective cohort study, 415 adults (300 patients with OSA and 115 patients without OSA) with a history of snoring and/or witnessed apneas or other suspected sleep breathing disorders were consecutively enrolled and followed up for three successive years to evaluate the development of cardiovascular events including acute coronary syndrome, cerebrovascular accidents (including ischemic or hemorrhagic strokes or transient ischemic attacks), death due to cardiac causes and all-cause mortality. Results: 415 patients were studied with a mean age of 56.2 ±15.7 years, 211 (50.8) of whom were male. Cardiovascular events developed in 15 participants (5%) of the OSA group, and 3 participants (2.6 %) of the OSA negative group. No significant differences were observed between the two groups in terms of the incidence of any of these events (P-value> 0.05). Using multiple logistic regression model (with P-value
- Published
- 2023
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