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Objectives: The objective of the study was to retrospectively evaluate the density of vessels exhibiting positive glycoprotein CD34 expression in the uterine leiomyosarcoma tissues and their correlation with the age of patients at the time of tumor diagnosis. Material and methods: The archival paraffin blocks with the cancer tissues collected from 50 patients suffering from uterine leiomyosarcoma were used together with their clinical and demographic data. The immunohistochemical peroxidase-de­pendent methods were used to detect microvessels with positive CD34 expression. The glycoprotein CD34 expression was evaluated as a density of microvessel showing the positive immunohistochemical reaction (MVD CD34 ). Results: The negative, statistically significant correlation between the age of patients (at the moment diagnosis) and the MVDCD34+ (R = –0.289, p = 0.042) was found. Conclusions: The study’s findings may suggest that the tissues of younger people constitute a permissive environment for pro-angiogenic factors.

Cesarean section is one of most common obstetric procedures, with the incidence of 33.9-43.1% of all labors in Poland. If the indication for cesarean section is 'immediate threat to maternal or fetal life', then the procedure must be performed without delay. The fact that time elapsed between decision to operate and delivery (decision-to-delivery interval, DDI) affects fetal outcome has been widely discussed. Poland lacks recommendations for optimal DDI in emergency cesarean section but some foreign scientific associations, universally recognized as an authority recommend DDI not to exceed 30 minutes in such cases. Our review attempts to determine the most significant factors affecting DDI, which can be divided according to the competence and responsibility of people involved in the functioning of the obstetrics department. Obstetrician-depending factors include appropriate diagnosis of indications for cesarean section and proficiency during procedure (incision-to-delivery interval). Midwives are responsible for preparation of the patient and the operating theater as well as transport of the patient. Anesthesiologists deem patients eligible for anesthesia and are also responsible for efficiency of its administration. Furthermore, few additional factors which seem to be fundamentally important in achieving optimal DDI have been identified and they depend on hospital management decisions, namely sufficient number of qualified staff, regular training in emergency procedures, availability of operating theaters, as well as fast and safe transportation of patients between the admission room, obstetrics department and operating theaters. In conclusion, we wish to emphasize that optimal DDI depends on proper collaboration of numerous teams, what may be important when discussing personal responsibility in obstetric failures.