1. Recurrence of ANCA-positive glomerulonephritis immediately after renal transplantation.
- Author
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Lobbedez T, Comoz F, Renaudineau E, Pujo M, Ryckelynck JP, and Hurault de Ligny B
- Subjects
- Aged, Cyclophosphamide therapeutic use, Glomerulonephritis complications, Glomerulonephritis drug therapy, Humans, Immunoglobulins, Intravenous therapeutic use, Immunosuppressive Agents therapeutic use, Kidney Failure, Chronic surgery, Kidney Transplantation, Male, Recurrence, Antibodies, Antineutrophil Cytoplasmic analysis, Glomerulonephritis immunology, Kidney Failure, Chronic immunology
- Abstract
Recurrence of crescentic necrotizing glomerulonephritis after renal transplantation is rare. Successful renal transplantation in patients with antineutrophil cytoplasmic autoantibody (ANCA) glomerulonephritis has been reported. The presence of ANCA at transplantation does not appear to increase the rate of relapse after kidney allografting. Therapy with cyclophosphamide and corticoids usually is effective. We report a case of recurrent perinuclear ANCA crescentic necrotizing glomerulonephritis immediately after renal transplantation that was treated successfully by cyclophosphamide, plasma exchange, and intravenous polyvalent immunoglobulin.
- Published
- 2003
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