1. Mimics of Allergy and Angioedema: Scombroid, Mast Cell Activation Disorders, and Hereditary Alpha Tryptasemia.
- Author
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Thomas EG and Thomas DJ
- Subjects
- Humans, Mast Cells physiology, Tryptases genetics, Mastocytosis diagnosis, Mastocytosis genetics, Mastocytosis, Systemic diagnosis, Mastocytosis, Systemic genetics, Mast Cell Activation Disorders, Angioedema diagnosis, Angioedema epidemiology, Angioedema etiology, Anaphylaxis diagnosis
- Abstract
Scombroid poisoning, systemic mastocytosis, and hereditary alpha tryptasemia all present with episodes that resemble allergic reactions. Knowledge regarding systemic mastocytosis and hereditary alpha tryptasemia is quickly evolving. Epidemiology, pathophysiology, and strategies to identify and diagnose are discussed. Evidence-based management in the emergency setting and beyond is also explored and summarized. Key differences are described between these events and allergic reactions., Competing Interests: Disclosure The authors declare that they have no relevant or material financial interests that relate to the research described in this article., (Copyright © 2022 Elsevier Inc. All rights reserved.)
- Published
- 2023
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