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The superficial mucocele is a rare variant of the common mucocele and noted microscopically by subepithelial pools of mucin. To increase the understanding of oral superficial mucoceles, a database was created from the demographics of case reports and case series from a PubMed search. At least 200 patients with superficial mucoceles have been described in the English-language literature, 82 of whom had biopsy-proven lesions; additional clinical information was available for 39 of these 82 patients. Compiled data suggest superficial mucoceles offered phenotypic distinctions from the common mucocele because they were more apt to occur in middle-aged women, often on the soft palate and buccal mucosa. Affected patients frequently had multiple lesions that were smaller than 3 mm and nearly 50% of patients developed recurrence. This report also describes the first histopathologically confirmed case of a superficial mucocele arising on the ventral tongue in a 22-year-old man. It is speculated that the glossal lesion might have developed from long-term impingement from exposed metal barbs from an orthodontic splint. Persistent lesions or atypical presentations underscore the need for histopathologic examination., (Copyright © 2015 The American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.)

Mucoceles can occur in the oral cavity, appendix, bladder, paranasal sinuses, and lacrimal sac. In the oral cavity, mucoceles arise from pathological alterations in the minor salivary gland ducts. In this study, we aimed to histologically reevaluate cases of oral mucoceles to identify possible variants. A total of 667 slides containing tissue sections stained with hematoxylin and eosin diagnosed as a phenomenon of mucus extravasation were analyzed under light microscopy by 4 previously trained examiners. In 128 cases (19.1%), 1 or more histopathological changes were identified. Twenty cases (2.9%) exhibited collagenous globular structures compatible with myxoglobulosis. In 30 cases (4.49%), dissociation of collagen fibers after mucin extravasation was observed. Fifty-four cases (8.09%) exhibited papillary synovial metaplasia-like change, and 32 (4.79%) showed a significant reduction in the lumen of the cavity due to large papillae. Twenty cases (2.9%) were compatible with superficial mucoceles, and in 11 cases (1.64%), the foamy macrophages showed an unusual solid arrangement, known as clear cell change. It is essential to recognize the possible histopathological changes in oral mucoceles to avoid diagnostic pitfalls., (Copyright © 2016 Elsevier Inc. All rights reserved.)

To thoroughly understand the biology of any lesion and render the appropriate management, clear and accurate definitions are paramount. For benign cysts and tumors of the oral maxillofacial region, an accurate depiction of these lesions needs to be elucidated to provide both the treating surgeon and the patient with a clear understanding of the course of treatment and the outcome., (Copyright © 2012 Elsevier Inc. All rights reserved.)

Purpose: To study the epidemiology of oral soft tissue lesions in New Zealand from 2002 to 2006 and to determine the concordance between the clinical diagnosis and the definitive histopathologic diagnosis achieved by general dental practitioners and by specialists., Materials and Methods: The details from biopsy referrals and the corresponding histopathologic reports of oral soft tissue lesions were recorded into a statistical software package, and the concordance between the clinical diagnosis and histopathologic diagnosis was determined for all the lesions., Results: Most biopsies were benign lesions, and both clinician groups achieved a high diagnostic concordance for these lesions. However, when considering all lesion types, the overall concordance for both groups was a moderate 50.6%, with little difference between specialists and general dental practitioners, although specialists were more accurate in diagnosing a malignant or premalignant lesion., Conclusions: The clinical and histopathologic concordance achieved by oral health practitioners in New Zealand appears to be moderate., (Copyright © 2011 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.)

Purpose: The present study was undertaken to evaluate mucoceles in the oral cavity of pediatric patients, including the clinical characteristics, treatment, and progress of the lesions., Patients and Methods: A retrospective study was performed from the medical records of patients (0-14 years old) treated for oral mucoceles between 1998 and 2008 in a reference children's hospital. All subjects with mucoceles on lips, mouth, buccal mucosa, and palate were included. The following data were recorded: age, gender, history of trauma, location, size, progression, time before diagnosis, treatment, histologic type, follow-up time, and recurrence., Results: A total of 89 patients (mean age, 6.1 years) participated in this study. There were 89 mucoceles: 4 were congenital; 79.8% were located on the lower lip; and 69% were larger than 5 mm in diameter. Average progression time was 5.7 months (range, 1-24 months). It was observed that older patients developed more mucoceles on the tongue and lips and younger patients developed more mucoceles on the buccal mucosa and palate. The lesions of 39 subjects resolved spontaneously; 50 were removed but 4 reappeared afterward. Histologically, all lesions were extravasation mucoceles., Conclusion: Mucoceles were more commonly located on the lower lip; 43.8% resolved spontaneously and 8% of the surgically removed mucoceles reappeared., (Copyright © 2010 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.)

A 37-year-old woman presented with acute right lower abdominal pain. Intraoperatively, the appendix was enlarged and distended. The lumen of the appendix was tightly filled with pearl-like globules, diagnostic of myxoglobulosis, a rare variant of mucocele of the appendix. A carcinoid of 2.0 cm diameter was found in the proximal region of the appendix. The appendiceal mucosa showed hyperplastic-adenomatous changes. A pseudodiverticulum interpreted as evidence of increased intraluminal pressure was detected. The latter may be an adjunct to the proximal partial obstruction of the appendiceal lumen by the carcinoid in the development of the spheroids of myxoglobulosis.

Allergic fungal sinusitis has been known to pathologists for two decades. During this time, multiple articles have stressed that the condition continues to be underdiagnosed. This is true, but it can also be overdiagnosed. This means that series of cases used for clinical studies usually are "contaminated" with cases that are misdiagnosed. Because the condition is often quite problematic to control, determination of the best treatment regimens is important. This will be dependent on clinical studies including only correctly diagnosed cases for study. This article discusses the steps toward making the correct diagnosis.

Mucous cell proliferation in a periapical radicular cyst from a patient with a family history of colonic malignancies and multiple sebaceous neoplasms of the skin, so-called Muir-Torre syndrome, is reported. Such goblet cell hyperplasia has not been previously reported to be associated with any known syndrome. We believe the finding of mucous cell hyperplasia in an odontogenic cyst may not simply be coincidental, but should raise suspicion of paraneoplastic potential and warrant further evaluation for possible occult neoplastic disease.

The canalicular adenoma is an uncommon, benign salivary gland neoplasm that usually occurs in or near the upper lip of elderly patients. A histologic study of 49 tumors revealed that they are often multifocal, may infiltrate their capsule, and are occasionally unencapsulated. Based on these findings, the method of treatment, as well as a differential diagnosis of minor salivary gland lesions, is discussed.