1. Histopathological Differences of the Pedicle Artery in Commonly Used Free Flaps: The Influence of Age, Gender, and Side.
- Author
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Ghassemi A, Köhlen D, Braunschweig T, Modabber A, Prescher A, and Nanhekhan L
- Subjects
- Age Factors, Aged, Aged, 80 and over, Atherosclerosis pathology, Cadaver, Calcinosis pathology, Epigastric Arteries pathology, Female, Fibula blood supply, Humans, Iliac Artery pathology, Male, Middle Aged, Necrosis, Plaque, Atherosclerotic pathology, Radial Artery pathology, Scapula blood supply, Sex Factors, Tunica Intima pathology, Tunica Media pathology, Arteries pathology, Free Tissue Flaps blood supply
- Abstract
Purpose: The increasing use of vascularized free flaps has increased the demand for a specified flap selection. This study investigated histologic differences in the arterial wall of the pedicle for commonly used free flaps and the effect of age, gender, and anatomic side on these differences., Materials and Methods: Light microscopic examinations of vessel walls were performed on 245 specimens of the nourishing artery of commonly used free vascularized flaps in preserved cadavers. The peroneal artery (PA), radial artery (RA), inferior epigastric artery (IEA), deep circumflex iliac artery (DCIA), and circumflex scapular artery (CSA) were examined. Differences of histologic changes in the arterial wall and the effect of age, gender, and body side were investigated., Results: All examined vessel specimens (age range, 62 to 98 yr; mean age, 83 yr; 15 female and 12 male) displayed mostly Class II changes. PA showed the greatest atherosclerotic changes, followed by the RA, IEA, DCIA, and CSA. Age had a meaningful effect on PA and RA. Anatomic side was important for PA and DCIA, whereas gender had a minor influence on vessel condition., Conclusion: The vessel wall of different flaps showed different atherosclerotic changes depending on age, anatomic side, and gender. These differences should be considered in flap selection., (Copyright © 2016 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.)
- Published
- 2016
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