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Predicting Fetal Prognosis by Assessing Fetal and Maternal Blood Flow Patterns in Pregnancies with Fetal Growth Restriction Introduction. Fetal growth restriction (FGR) is associated with prematurity and a number of complications, as well as long-term impact on metabolic or cardiac function in adults. Aim of the Study. To study the prognostic value of staging maternal and fetal Doppler blood flow velocities in women with FGR; and evaluate prenatal characteristics as possible risk factors for severe vascular abnormalities. Materials and methods. 70 singleton pregnancies complicated by FGR were included in prospective follow-up study. Blood flow velocities in the uterine (UtA), umbilical (AU), middle cerebral (ACM) arteries and ductus venosus (DV) were measured. FGR neonates grouped as follows: I) normal blood velocity waveforms; II) abnormal UtA velocimetry and/or presence of early diastolic "notch"; III) abnormal AU without signs of "brain sparing"; IV) abnormal AU and ACM pulsatility index (PI) and V) AU absent or reversed end diastolic flow and an abnormal DV. Prenatal risk factors and perinatal outcome were assessed in relation to these Doppler blood flow patterns and compared with Fisher exact and Pearson c2 test. Results. There was a strong correlation between the severity of grouping and birth weight (p

TRAP sequence-is a rare, serious malformation with reported incidence 0.3 in 10.000 pregnancies. The prognoses is lethal for the recipient, whereas perinatal mortality and malformation risks are up to 50 % and 10% in pumping twin. We present three cases of TRAP sequence diagnosed and followed at our institution from August to October 2011. Outcome of TRAP sequence depends on the time of diagnoses, treatment modality and timely delivery.