Search

Geological records of mountain glacier fluctuations provide useful evidence for tracing the magnitude and rate of past temperature change. In this study, we present air temperature reconstructions for the last glacial termination in New Zealand derived using snowline reconstructions and numerical glacier modelling. We target the Arthur's Pass moraines in the Otira River catchment, which have previously been dated to the Lateglacial using cosmogenic 10Be. Recalculation of these exposure ages using a locally calibrated 10Be production rate indicates that these moraines formed ca. 16–14 ka. Our glacier modelling experiments and snowline reconstructions exhibit good agreement and show that the Arthur's Pass moraines formed in a climate that was 2.2–3.5 °C colder than present. Combining our results with other, proximal glacier records shows that ice in this catchment retreated ca. 50 km from the coastal plain to the main divide during the interval 17–15 ka, in response to a temperature increase of at least ca. 3 °C. Over half of this retreat occurred after the glacier had withdrawn from an overdeepened basin. Thus, we conclude that temperature increase was the primary driver of widespread and rapid glacier retreat in New Zealand at the onset of the last glacial termination.

Dexmedetomidine has established a firm position in the armamentarium of anesthesia pharmacology. However, it is still a relatively new drug and its application is based on early evidence that is intriguing but far from conclusive. Based on experience with previous cure-alls, anesthesia clinicians and researchers must insist on more information and formulate appropriate science that will allow us to truly understand the role of this dexmedetomidine in our specialty—as wonder drug or also-ran.

Net accumulation measurements from two glaciers located on opposite sides of the New Zealand Southern Alps were used to explore processes controlling spatial variability. The degree of variability, as measured by the spatial variogram, differed in each of the three successive years, but the lowest variance occurred on both glaciers in March 2008, after a hot and dry summer. Strong relationships between net accumulation and elevation within the accumulation area were only found on Franz Josef Glacier (FJG), despite this being the primary control used in glacier mass balance modelling. Interaction between wind and topography was found to be important to the distribution of net accumulation on both glaciers. The crevasse stratigraphy method is an ideal way to gain good spatial coverage of net accumulation, and particularly suited to glaciers with high annual precipitation. Copyright © 2010 John Wiley & Sons, Ltd.

The earliest or patch stage of mycosis fungoides may present diagnostic difficulty both clinically and pathologically. The present study of the polymerase chain reaction (PCR) as a diagnostic tool in early mycosis fungoides was therefore undertaken, using a rapid PCR method for the detection of gamma- and beta-chain T-cell receptor (TCR) gene rearrangements in routine formalin-fixed, paraffin-embedded histological sections. Forty-two biopsies were studied from 26 patients with mycosis fungoides. Twenty-three skin biopsies with a clinicopathological diagnosis of early, or patch stage, mycosis fungoides were investigated. Of these, 18 (78 per cent) showed TCR-gamma or both beta- and gamma-chain TCR gene rearrangements. TCR gene rearrangements were shown in seven of the 14 plaque stage lesions (50 per cent) and also in the single case of tumour stage disease. Where gene rearrangements were identified, these were identical in all biopsies from an individual patient, irrespective of the site of the lesion, the disease stage, or the time lapse between the biopsies. The PCR is therefore a highly sensitive technique, which can be performed on routine pathological material, in cases where the diagnosis of early mycosis fungoides cannot be made with certainty on conventional histopathological and immunohistochemical grounds.