1. Cortical reorganization in linear nevus sebaceous syndrome: a multimodality neuroimaging study.
- Author
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Levy-Reis I, Casasanto DJ, Gonzalez JB, Alsop DC, Glosser G, Maldjan JA, French J, and Detre JA
- Subjects
- Adult, Brain abnormalities, Contrast Media, Electroencephalography, Epilepsy diagnosis, Humans, Image Enhancement, Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy, Male, Seizures diagnosis, Tomography, Emission-Computed, Tomography, Emission-Computed, Single-Photon, Brain Diseases diagnosis, Cerebral Cortex pathology, Diagnostic Imaging, Neurocutaneous Syndromes diagnosis, Nevus diagnosis
- Abstract
The authors report the findings of multimodal structural, functional, and metabolic imaging in a patient with linear nevus sebaceous syndrome, intractable seizures, and right megalencephaly. Despite nearly continuous paroxysmal electrical activity from the megalencephalic region, imaging studies suggested nonfunctional tissue in this region with reorganization of cortical function to the unaffected ipsilateral hemisphere. Hemispherectomy has been successfully performed in previous patients; however, it could have led to marked left hemiparesis with significant functional morbidity in this patient because of ipsilateral reorganization of the primary motor cortex.
- Published
- 2000
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