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Molluscum contagiosum (MC) is common skin infection caused by molluscum virus. Growth of MC inside melanocytic lesion is extremely rare. We present the case of MC in common melanocytic nevus and the first case of MC in superficial spreading malignant melanoma. Complete destruction of melanocytes and melanoma cells occurred on the site of MC infection. MC virus might be considered as a future candidate for viral oncolysis in cutaneous melanoma patients with advanced disease.

Acanthosis nigricans (AN) is a disorder often accompanied by internal malignancy in adult patients, but in children it is usually benign. Generalized forms of AN, especially in childhood, are extremely rare. We report a 5-year-old boy with a 3-year history of AN who had generalized roughness and hyperpigmentation, numerous skin wrinkles, disseminated skin tags, tripe palms, and intensive pruritus. No clinical evidence of internal disorders, notably of an endocrinologic or neoplastic nature, have been detected thus far.