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Your search keyword '"Dosquet, Christine"' showing total 15 results
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15 results on '"Dosquet, Christine"'

1. Autologous 111 Indium‐oxinate‐labelled platelet sequestration study in patients with immune thrombocytopenia treated by thrombopoietin receptor‐agonists

Author

Mahevas, Matthieu, primary, Van Eeckhoudt, Sandrine, additional, Moulis, Guillaume, additional, Limal, Nicolas, additional, Languille, Laetitia, additional, Bierling, Philippe, additional, Dossier, Antoine, additional, Duriez, Frédéric, additional, Galicier, Lionel, additional, Morin, Anne‐Sophie, additional, Tamburini, Jérôme, additional, Chaoui, Driss, additional, Bouscary, Didier, additional, Jijakli, Ahmad A. L., additional, Khellaf, Mehdi, additional, Vaida, Ioana, additional, Michel, Marc, additional, Vercellino, Laetitia, additional, Jaddi, Hind, additional, Yollant, Armelle, additional, Dosquet, Christine, additional, Godeau, Bertrand, additional, and Chomienne, Christine, additional

Published
2019
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3. Hind limb unloading, a model of spaceflight conditions, leads to decreased B lymphopoiesis similar to aging

Author

Lescale, Chloe, primary, Schenten, Veronique, additional, Djeghloul, Dounia, additional, Bennabi, Meriem, additional, Gaignier, Fanny, additional, Vandamme, Katleen, additional, Strazielle, Catherine, additional, Kuzniak, Isabelle, additional, Petite, Herve, additional, Dosquet, Christine, additional, Frippiat, Jean‐Pol, additional, and Goodhardt, Michele, additional

Published
2014
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4. Efficacy and safety of pegylated‐interferon α‐2a in myelofibrosis: a study by the FIM and GEM French cooperative groups

Author

Ianotto, Jean‐Christophe, primary, Boyer‐Perrard, Françoise, additional, Gyan, Emmanuel, additional, Laribi, Kamel, additional, Cony‐Makhoul, Pascale, additional, Demory, Jean‐Loup, additional, De Renzis, Benoit, additional, Dosquet, Christine, additional, Rey, Jerome, additional, Roy, Lydia, additional, Dupriez, Brigitte, additional, Knoops, Laurent, additional, Legros, Laurence, additional, Malou, Mohamed, additional, Hutin, Pascal, additional, Ranta, Dana, additional, Schoenwald, Michele, additional, Andreoli, Annalisa, additional, Abgrall, Jean‐François, additional, and Kiladjian, Jean‐Jacques, additional

Published
2013
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5. Age-related changes in human hematopoietic stem/progenitor cells

Author

Kuranda, Klaudia, primary, Vargaftig, Jacques, additional, de la Rochere, Philippe, additional, Dosquet, Christine, additional, Charron, Dominique, additional, Bardin, Florence, additional, Tonnelle, Cecile, additional, Bonnet, Dominique, additional, and Goodhardt, Michele, additional

Published
2011
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8. Mutations in exon 12 of JAK2 are mainly found in JAK2 V617F-negative polycythaemia vera patients

Author

Kouroupi, Eirini, primary, Zoi, Katerina, additional, Parquet, Nathalie, additional, Zoi, Christine, additional, Kiladjian, Jean-Jacques, additional, Grigoraki, Vassiliki, additional, Vainchenker, William, additional, Lellouche, Franck, additional, Marzac, Christophe, additional, Schlageter, Marie-Hélène, additional, Dosquet, Christine, additional, Scott, Linda M., additional, Fenaux, Pierre, additional, Loukopoulos, Dimitris, additional, Chomienne, Christine, additional, and Cassinat, Bruno, additional

Published
2008
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10. ABO-mismatched marrow processing for transplantation: results of 114 procedures and analysis of immediate adverse events and hematopoietic recovery

Author

Larghero, Jerome, primary, Rea, Delphine, additional, Esperou, Helene, additional, Biscay, Nicole, additional, Maurer, Marie-Noelle, additional, Lacassagne, Marie-Noelle, additional, Ternaux, Brigitte, additional, Traineau, Richard, additional, Yakouben, Karima, additional, Dosquet, Christine, additional, Socie, Gerard, additional, Gluckman, Eliane, additional, Benbunan, Marc, additional, and Marolleau, Jean-Pierre, additional

Published
2006
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15. VEGF and VEGFR-1 are coexpressed by epithelial and stromal cells of renal cell carcinoma.

Author

Rivet J, Mourah S, Murata H, Mounier N, Pisonero H, Mongiat-Artus P, Teillac P, Calvo F, Janin A, and Dosquet C

Subjects
Adult, Aged, Aged, 80 and over, Carcinoma, Renal Cell pathology, Epithelial Cells chemistry, Female, Fluorescent Antibody Technique, Humans, Keratins analysis, Keratins genetics, Kidney Neoplasms pathology, Male, Microdissection, Middle Aged, RNA, Messenger analysis, Reverse Transcriptase Polymerase Chain Reaction, Stromal Cells chemistry, Vascular Endothelial Growth Factor A genetics, Vascular Endothelial Growth Factor Receptor-1 genetics, Vascular Endothelial Growth Factor Receptor-2 analysis, Vascular Endothelial Growth Factor Receptor-2 genetics, Carcinoma, Renal Cell chemistry, Kidney Neoplasms chemistry, Vascular Endothelial Growth Factor A analysis, Vascular Endothelial Growth Factor Receptor-1 analysis
Abstract

Background: Tumor angiogenesis is a dynamic process that plays a major role in cancer progression. Vascular endothelial growth factor (VEGF) and its receptors play a pivotal role in angiogenesis. The expression of VEGF and its receptors VEGFR-1 and VEGFR-2 in renal cell carcinoma (RCC) was investigated in the perspective of anti-VEGF treatments., Methods: Total VEGF protein levels were quantified by enzyme-linked immunosorbent assay (ELISA) in tumor tissue samples from surgical specimens of 65 patients with clear cell RCC. At the cellular level the VEGF isoforms VEGFR-1 and VEGFR-2 mRNA were quantified by real-time quantitative reverse-transcriptase polymerase chain reaction (RT-PCR) in laser-microdissected tumoral epithelial as stromal cells and in corresponding normal tissue compartments. Colocalization of VEGF and VEGFR-1 proteins was studied by triple immunofluorescent labeling., Results: Protein VEGF in cytosolic extracts was significantly higher in tumoral than in nontumoral tissue (P< .0001). Event-free survival was significantly longer for patients with cytosolic VEGF lower than the cutoff (75th percentile of VEGF protein levels, P= .02). In laser-microdissected epithelial cells, VEGF(121) and VEGFR-1 mRNA expressions were higher in RCC than in corresponding nontumoral kidney (P= .007 and P= .002, respectively); they were also higher in stromal cells of RCC compared with nontumoral kidney (P= .02 and P= .003, respectively). There was no differential VEGFR-2 expression in epithelial or in stromal cells of tumoral or nontumoral kidney. By immunofluorescent labeling VEGF and VEGFR-1 colocalized on RCC tumor epithelial and stromal cells., Conclusions: Combined laser microdissection and quantitative RT-PCR, as triple immunofluorescent labeling, underlined the preferential expression of the most soluble VEGF isoform, VEGF(121), and its receptor VEGFR-1, but not VEGFR-2, in epithelial and stromal cells of RCC.

Published
2008
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