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Your search keyword '"Douglas Mans"' showing total 2 results
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2 results on '"Douglas Mans"'

1. ChemInform Abstract: Synthesis of Fused Dihydropyrano(furano)pyridines via [4 + 2]-Cycloaddition of 5-Alkenoxy Substituted Oxazoles

Author

Steven N. Goodman, Joseph Sisko, Hao Yin, and Douglas Mans

Subjects
chemistry.chemical_classification, chemistry.chemical_compound, chemistry, Organic chemistry, General Medicine, Cycloaddition, Oxazole, Amino acid
Abstract

A three-step procedure to access fused pyridines has been developed utilizing inexpensive amino acids and alkenols to form the key oxazole precursors. Yields are good to excellent and provide a rapid and inexpensive route to a range of pharmacologically and biologically valuable fused pyridines with difficult to access substitution patterns.

Published
2012
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2. ChemInform Abstract: An Expedient Synthesis of cis/trans-1,3-Disubstituted Cyclobutanols

Author

Joseph Sisko, Stacy A. O'Neill-Slawecki, Justin Morin, Stacie Calad, and Douglas Mans

Subjects
chemistry.chemical_classification, chemistry, medicine, General Medicine, Vinyl ether, Medicinal chemistry, Cis–trans isomerism, Cycloaddition, Alkyl, medicine.drug
Abstract

3-Alkoxycyclobutanones such as (IV) are obtained from [2 + 2] cycloaddition of alkyl vinyl ether and chloroketene followed by hydrogenolytic dechlorination.

Published
2011
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