1. Synthetic Enzyme‐Catalyzed CO 2 Fixation Reactions
- Author
-
Godwin A. Aleku, George W. Roberts, David Leys, and Gabriel R. Titchiner
- Subjects
biology ,Artificial enzyme ,Chemistry ,General Chemical Engineering ,Carbon fixation ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Combinatorial chemistry ,0104 chemical sciences ,Catalysis ,Organic molecules ,Chemical production ,Fixation (surgical) ,General Energy ,Carboxylation ,Biocatalysis ,biology.protein ,Environmental Chemistry ,General Materials Science ,0210 nano-technology - Abstract
In recent years, (de)carboxylases that catalyze reversible (de)carboxylation have been targeted for application as carboxylation catalysts. This has led to the development of proof-of-concept (bio)synthetic CO2 fixation routes for chemical production. However, further progress towards industrial application has been hampered by the thermodynamic constraint that accompanies fixing CO2 to organic molecules. In this Review, biocatalytic carboxylation methods are discussed with emphases on the diverse strategies devised to alleviate the inherent thermodynamic constraints and their application in synthetic CO2 -fixation cascades.
- Published
- 2021
- Full Text
- View/download PDF