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6 results on '"Harris, S. C."'

5. Initial experience of clinical pharmacology and clinical pharmacy interactions in a clinical pharmacokinetics consultation service.

Author

Taylor JW, McLean AJ, Leonard RG, Ludden TM, Clibon U, du Souich BP, Harris SC, Lalka D, Talbert RL, Vicuna N, Walton CA, and McNay JL

Subjects
Drug Administration Schedule, Drug-Related Side Effects and Adverse Reactions, Evaluation Studies as Topic, Hospital Bed Capacity, 500 and over, Hospitals, Veterans, Humans, Kinetics, Texas, Drug Information Services statistics & numerical data, Information Services statistics & numerical data, Pharmaceutical Preparations metabolism, Pharmacy Service, Hospital statistics & numerical data, Referral and Consultation
Published
1979
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6. Xanthogranulomatous pyelonephritis: a pathological, clinical and aetiological analysis of 87 cases.

Author

Parsons MA, Harris SC, Longstaff AJ, and Grainger RG

Subjects
Adolescent, Adult, Aged, Biopsy, Diagnosis, Differential, Female, Granuloma diagnosis, Granuloma etiology, Humans, Kidney Neoplasms complications, Male, Middle Aged, Pyelonephritis diagnosis, Pyelonephritis etiology, Urinary Calculi complications, Urinary Tract Infections complications, Urination Disorders complications, Xanthomatosis diagnosis, Xanthomatosis etiology, Granuloma pathology, Pyelonephritis pathology, Xanthomatosis pathology
Abstract

Analysis of 87 cases of xanthogranulomatous pyelonephritis ( XPN ) from 1958 to 1983 (14 males, 73 females, ages 13-85) revealed an incidence of 1.4 cases/100 000 population per annum which is apparently increasing. Clinical, radiological and pathological investigations demonstrated universal urinary obstruction (77.5 per cent calculi, 17.5 per cent pelviureteric junction obstruction) and pathogenic organisms such as E. coli or Proteus were cultured from the urine in 72 per cent of cases. Rare complications included sinuses or fistulae to bowel. We believe that the combination of urinary obstruction and infection by organisms of low virulence initiate XPN , and that associated lipid is derived from renal pelvic adipose tissue. Problems of differential diagnosis are discussed in relation to the use of immunocytochemistry and electron microscopy.

Published
1983

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