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Your search keyword '"Hilker, Rüdiger"' showing total 18 results
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18 results on '"Hilker, Rüdiger"'

1. Manual MRI morphometry in Parkinsonian syndromes

Author

Möller, Leona, Kassubek, Jan, Möller, Franz, Schnitzler, Alfons, Oertel, Wolfgang H, Knake, Susanne, Huppertz, Hans-Jürgen, Höglinger, Günter U, Südmeyer, Martin, Hilker, Rüdiger, Hattingen, Elke, Egger, Karl, Amtage, Florian, Pinkhardt, Elmar H, Respondek, Gesine, and Stamelou, Maria

Subjects
Adult, Aged, 80 and over, Male, Reproducibility of Results, Middle Aged, diagnostic imaging [Multiple System Atrophy], diagnostic imaging [Parkinsonian Disorders], Magnetic Resonance Imaging, physiopathology [Multiple System Atrophy], ROC Curve, Case-Control Studies, physiopathology [Parkinsonian Disorders], diagnostic imaging [Parkinson Disease], Humans, Female, ddc:610, diagnostic imaging [Supranuclear Palsy, Progressive], diagnostic imaging [Brain], Aged
Abstract

Manual MRI morphometry in Parkinsonian syndromes.

Published
2017

2. Manual MRI morphometry in Parkinsonian syndromes

Author

Möller, Leona, primary, Kassubek, Jan, additional, Südmeyer, Martin, additional, Hilker, Rüdiger, additional, Hattingen, Elke, additional, Egger, Karl, additional, Amtage, Florian, additional, Pinkhardt, Elmar H., additional, Respondek, Gesine, additional, Stamelou, Maria, additional, Möller, Franz, additional, Schnitzler, Alfons, additional, Oertel, Wolfgang H., additional, Knake, Susanne, additional, Huppertz, Hans-Jürgen, additional, and Höglinger, Günter U., additional

Published
2017
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3. Differentiation of neurodegenerative parkinsonian syndromes by volumetric magnetic resonance imaging analysis and support vector machine classification

Author

Huppertz, Hans-Jürgen, primary, Möller, Leona, additional, Südmeyer, Martin, additional, Hilker, Rüdiger, additional, Hattingen, Elke, additional, Egger, Karl, additional, Amtage, Florian, additional, Respondek, Gesine, additional, Stamelou, Maria, additional, Schnitzler, Alfons, additional, Pinkhardt, Elmar H., additional, Oertel, Wolfgang H., additional, Knake, Susanne, additional, Kassubek, Jan, additional, and Höglinger, Günter U., additional

Published
2016
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6. Is improvement in the quality of life after subthalamic nucleus stimulation in Parkinson's disease predictable?

Author

Daniels, Christine, primary, Krack, Paul, additional, Volkmann, Jens, additional, Raethjen, Jan, additional, Pinsker, Markus O., additional, Kloss, Manja, additional, Tronnier, Volker, additional, Schnitzler, Alfons, additional, Wojtecki, Lars, additional, Bötzel, Kai, additional, Danek, Adrian, additional, Hilker, Rüdiger, additional, Sturm, Volker, additional, Kupsch, Andreas, additional, Karner, Elfriede, additional, Deuschl, Günther, additional, and Witt, Karsten, additional

Published
2011
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7. Dysphagia in symptomatic palatal tremor

Author

van de Loo, Simone, primary, Somasundaram, Sriramya, additional, Wagner, Marlies, additional, Singer, Oliver C., additional, Steinmetz, Helmuth, additional, and Hilker, Rüdiger, additional

Published
2010
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8. Risk factors for executive dysfunction after subthalamic nucleus stimulation in Parkinson's disease

Author

Daniels, Christine, primary, Krack, Paul, additional, Volkmann, Jens, additional, Pinsker, Markus O., additional, Krause, Martin, additional, Tronnier, Volker, additional, Kloss, Manja, additional, Schnitzler, Alfons, additional, Wojtecki, Lars, additional, Bötzel, Kai, additional, Danek, Adrian, additional, Hilker, Rüdiger, additional, Sturm, Volker, additional, Kupsch, Andreas, additional, Karner, Elfriede, additional, Deuschl, Günther, additional, and Witt, Karsten, additional

Published
2010
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13. Lewy body Parkinson's disease in a large pedigree with 77Parkin mutation carriers

Author

Pramstaller, Peter P., primary, Schlossmacher, Michael G., additional, Jacques, Thomas S., additional, Scaravilli, Francesco, additional, Eskelson, Cordula, additional, Pepivani, Imelda, additional, Hedrich, Katja, additional, Adel, Susanna, additional, Gonzales-McNeal, Melissa, additional, Hilker, Rüdiger, additional, Kramer, Patricia L., additional, and Klein, Christine, additional

Published
2005
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17. Diffusion tensor imaging of white matter involvement in essential tremor.

Author

Klein JC, Lorenz B, Kang JS, Baudrexel S, Seifried C, van de Loo S, Steinmetz H, Deichmann R, and Hilker R

Subjects
Adult, Aged, Anisotropy, Female, Humans, Male, Middle Aged, Brain pathology, Brain Mapping methods, Diffusion Tensor Imaging, Essential Tremor pathology
Abstract

This study set out to determine whether there is white matter involvement in essential tremor (ET), the most common movement disorder. We collected diffusion MRI and analysed differences in fractional anisotropy (FA) and mean diffusivity (MD) between ET patients and control subjects as markers of white matter integrity. We used both classical ROI-based statistics and whole-brain analysis techniques, including voxel-wise analysis with SPM5 and tract-based spatial statistics (TBSS). Using region of interest (ROI) analysis, we found increased MD bilaterally in the inferior cerebellar peduncles (ICP) and reduced FA in the right-sided ICP of ET patients. Whole-brain analyses with TBSS detected increased MD distributed in both motor and nonmotor white matter fibers of ET patients predominantly in the left parietal white matter, while there were no significant FA differences in these areas between ET patients and controls. Voxel-wise analysis with SPM detected significant increase of MD congruent with the highest probability of difference as detected by TBSS. VBM analysis of T1 images did not detect significant differences in either gray or white matter density between our study groups. In summary, we found evidence for changes in white matter MRI properties in ET. The circumscript pathology of the ICP corroborates the pathogenetic concept of the cerebellum and its projections as key structures for tremor generation in ET. Moreover, increased diffusivity in white matter structures of both hemispheres suggests widespread alterations of fiber integrity in motor and nonmotor networks in ET patients. The underlying cause of the DTI changes observed remains to be elucidated.

Published
2011
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18. Rapid single-scan T2*-mapping using exponential excitation pulses and image-based correction for linear background gradients.

Author

Baudrexel S, Volz S, Preibisch C, Klein JC, Steinmetz H, Hilker R, and Deichmann R

Subjects
Female, Humans, Male, Middle Aged, Reproducibility of Results, Sensitivity and Specificity, Algorithms, Artifacts, Brain anatomy & histology, Image Enhancement methods, Image Interpretation, Computer-Assisted methods
Abstract

A method for fast quantitative T(2)* mapping based on multiple gradient-echo (multi-GE) imaging with correction for static magnetic field inhomogeneities is described, using an exponential excitation pulse. Field gradient maps are obtained from the phase information and modulus data are subsequently corrected, allowing for simple monoexponential T(2)* fitting. Echoes with long echo times suffering from major signal losses due to field inhomogeneities are excluded from the analysis. The acquisition time for a matrix size of 256 x 256, 1 mm in-plane resolution, and 2 mm slice thickness amounts to 15 s per slice. An additional correction for in-plane field gradients further improves accuracy. Phantom experiments show that the method provides accurate T(2)* values for field gradients up to 200 microT/m; for gradients up to 300 microT/m errors do not exceed 15%. In vivo T(2)* values acquired on healthy volunteers at 3T are in excellent agreement with results from the literature., ((c) 2009 Wiley-Liss, Inc.)

Published
2009
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