1. Clinical response to sodium glucose co‐transporter 2 inhibitor ipragliflozin in a patient with metastatic renal cell carcinoma
- Author
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Keita Izumi, Yasumasa Iimura, Kiyoshi Hiruma, Tsuguhiro Touma, and Tetsuro Tsukamoto
- Subjects
diabetes mellitus ,renal cell carcinoma ,sodium glucose transporter 2 inhibitor ,Diseases of the genitourinary system. Urology ,RC870-923 - Abstract
Introduction Sodium glucose co‐transporter 2 inhibitors constitute a new class of antidiabetic medication. Sodium glucose co‐transporter 2 inhibitors have been shown to exert anticancer effects. However, the clinical value of these drugs as anticancer agents is yet to be evaluated. Case presentation A 72‐year‐old man presented to our hospital with frequent cough and dyspnea. Contrast‐enhanced computed tomography revealed renal cell carcinoma cT3bN0M1. Ipragliflozin, a sodium glucose co‐transporter 2 inhibitor, treatment was initiated to control blood glucose levels. Two years after diagnosis, computed tomography revealed remarkable tumor regression without any systemic therapy other than ipragliflozin. Conclusion Sodium glucose co‐transporter 2 inhibitors are potentially applicable as anticancer agents among patients with metastatic renal cell carcinoma.
- Published
- 2019
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