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Your search keyword '"Lan, Hui‐Yao"' showing total 28 results
Start Over Author "Lan, Hui‐Yao" Publisher wiley
28 results on '"Lan, Hui‐Yao"'

1. Hematopoietic Transcription Factor RUNX1 is Essential for Promoting Macrophage–Myofibroblast Transition in Non‐Small‐Cell Lung Carcinoma (Adv. Sci. 1/2024)

Author

Tang, Philip Chiu‐Tsun, primary, Chan, Max Kam‐Kwan, additional, Chung, Jeff Yat‐Fai, additional, Chan, Alex Siu‐Wing, additional, Zhang, Dongmei, additional, Li, Chunjie, additional, Leung, Kam‐Tong, additional, Ng, Calvin Sze‐Hang, additional, Wu, Yi, additional, To, Ka‐Fai, additional, Lan, Hui‐Yao, additional, and Tang, Patrick Ming‐Kuen, additional

Published
2024
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2. Hematopoietic Transcription Factor RUNX1 is Essential for Promoting Macrophage–Myofibroblast Transition in Non‐Small‐Cell Lung Carcinoma

Author

Tang, Philip Chiu‐Tsun, primary, Chan, Max Kam‐Kwan, additional, Chung, Jeff Yat‐Fai, additional, Chan, Alex Siu‐Wing, additional, Zhang, Dongmei, additional, Li, Chunjie, additional, Leung, Kam‐Tong, additional, Ng, Calvin Sze‐Hang, additional, Wu, Yi, additional, To, Ka‐Fai, additional, Lan, Hui‐Yao, additional, and Tang, Patrick Ming‐Kuen, additional

Published
2023
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5. Smad3 Promotes Cancer‐Associated Fibroblasts Generation via Macrophage–Myofibroblast Transition (Adv. Sci. 1/2022)

Author

Tang, Philip Chiu‐Tsun, primary, Chung, Jeff Yat‐Fai, additional, Xue, Vivian Wei‐wen, additional, Xiao, Jun, additional, Meng, Xiao‐Ming, additional, Huang, Xiao‐Ru, additional, Zhou, Shuang, additional, Chan, Alex Siu‐Wing, additional, Tsang, Anna Chi‐Man, additional, Cheng, Alfred Sze‐Lok, additional, Lee, Tin‐Lap, additional, Leung, Kam‐Tong, additional, Lam, Eric W.‐F., additional, To, Ka‐Fai, additional, Tang, Patrick Ming‐Kuen, additional, and Lan, Hui‐Yao, additional

Published
2022
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6. Smad3 Promotes Cancer‐Associated Fibroblasts Generation via Macrophage–Myofibroblast Transition

Author

Tang, Philip Chiu‐Tsun, primary, Chung, Jeff Yat‐Fai, additional, Xue, Vivian Wei‐wen, additional, Xiao, Jun, additional, Meng, Xiao‐Ming, additional, Huang, Xiao‐Ru, additional, Zhou, Shuang, additional, Chan, Alex Siu‐Wing, additional, Tsang, Anna Chi‐Man, additional, Cheng, Alfred Sze‐Lok, additional, Lee, Tin‐Lap, additional, Leung, Kam‐Tong, additional, Lam, Eric W.‐F., additional, To, Ka‐Fai, additional, Tang, Patrick Ming‐Kuen, additional, and Lan, Hui‐Yao, additional

Published
2021
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7. AANG: A natural compound formula for overcoming multidrug resistance via synergistic rebalancing the TGF‐β/Smad signalling in hepatocellular carcinoma

Author

Chung, Jeff Yat‐Fai, primary, Chan, Max Kam‐Kwan, additional, Tang, Philip Chiu‐Tsun, additional, Chan, Alex Siu‐Wing, additional, Chung, Justin Shing‐Yin, additional, Meng, Xiao‐Ming, additional, To, Ka‐Fai, additional, Lan, Hui‐Yao, additional, Leung, Kam‐Tong, additional, and Tang, Patrick Ming‐Kuen, additional

Published
2021
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11. BAY61‐3606 protects kidney from acute ischemia/reperfusion injury through inhibiting spleen tyrosine kinase and suppressing inflammatory macrophage response

Author

Tan, Rui‐zhi, primary, Li, Jian‐chun, additional, Liu, Jian, additional, Lei, Xian‐ying, additional, Zhong, Xia, additional, Wang, Chen, additional, Yan, Ying, additional, Linda Ye, Lingyu, additional, Darrel Duan, Dayue, additional, Lan, Hui‐yao, additional, and Wang, Li, additional

Published
2020
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13. Macrophage migration inhibitory factor promotes renal injury induced by ischemic reperfusion

Author

Li, Jin H, primary, Tang, Ying, additional, Lv, Jun, additional, Wang, Xiao H., additional, Yang, Hui, additional, Tang, Patrick M. K., additional, Huang, Xiao R., additional, He, Zhi J., additional, Zhou, Zi J, additional, Huang, Qiu Y., additional, Klug, Jörg, additional, Meinhardt, Andreas, additional, Fingerle‐Rowson, Günter, additional, Xu, An P., additional, Zheng, Zhi H., additional, and Lan, Hui Yao, additional

Published
2019
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19. Renoprotective effect of berberine on type 2 diabetic nephropathy in rats

Author

Sun, Si‐Fan, primary, Zhao, Ting‐Ting, additional, Zhang, Hao‐Jun, additional, Huang, Xiao‐Ru, additional, Zhang, Wei‐Ku, additional, Zhang, Lei, additional, Yan, Mei‐Hua, additional, Dong, Xi, additional, Wang, Hua, additional, Wen, Yu‐Min, additional, Pan, Xin‐Ping, additional, Lan, Hui Yao, additional, and Li, Ping, additional

Published
2015
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25. Deregulation of E-cadherin-catenin complex in precancerous lesions of gastric adenocarcinoma

Author

CHAN, ANNIE ON-ON, primary, WONG, BENJAMIN CHUN-YU, additional, LAN, HUI-YAO, additional, LOKE, SHEE-LOONG, additional, CHAN, WAI-KONG, additional, HUI, WAI-MO, additional, YUEN, YUI-HUNG, additional, NG, IRENE, additional, HOU, LAURENCE, additional, WONG, WAI-MAN, additional, YUEN, MAN-FUNG, additional, LUK, JOHN MOON-CHING, additional, and LAM, SHIU-KUM, additional

Published
2003
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28. Quercetin protects against cisplatin-induced acute kidney injury by inhibiting Mincle/Syk/NF-κB signaling maintained macrophage inflammation.

Author

Tan RZ, Wang C, Deng C, Zhong X, Yan Y, Luo Y, Lan HY, He T, and Wang L

Subjects
Animals, Antioxidants pharmacology, Disease Models, Animal, Humans, Male, Mice, Quercetin pharmacology, Acute Kidney Injury chemically induced, Acute Kidney Injury drug therapy, Antioxidants therapeutic use, Cisplatin adverse effects, Inflammation drug therapy
Abstract

Acute kidney injury (AKI) with high incidence and mortality is the main cause of chronic kidney disease. Previous studies have indicated that quercetin, an abundant flavonoid in plants, exhibited renoprotective role in AKI. However, the underlying mechanism is largely unknown. In this study, we try to explore whether quercetin protects against AKI by inhibiting macrophage inflammation via regulation of Mincle/Syk/NF-κB signaling. The results demonstrated that quercetin can significantly inhibit expression and secretion of IL-1β, IL-6, and TNF-α in LPS-induced bone marrow-derived macrophages (BMDMs) and reduce activity of Mincle/Syk/NF-κB signaling in vitro. We also found that quercetin can strongly reduce the concentration of serum creatinine, BUN, IL-1β, IL-6, and TNF-α in cisplatin-induced AKI model. Furthermore, quercetin down-regulated protein levels of Mincle, phosphorylated Syk and NF-κB in kidney macrophages of AKI, as well as inhibited M1, up-regulated M2 macrophage activity. Notably, the down-regulation of LPS-induced inflammation by quercetin was reversed after adding TDB (an agonist of Mincle) in BMDMs, suggesting that quercetin suppresses macrophage inflammation may mainly through inhibiting Mincle and its downstream signaling. In summary, these findings clarified a new mechanism of quercetin improving AKI-induced kidney inflammation and injury, which provides a new drug option for the clinical treatment of AKI., (© 2019 John Wiley & Sons, Ltd.)

Published
2020
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