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Your search keyword '"Li, Xiao-Lin"' showing total 30 results
Start Over Author "Li, Xiao-Lin" Publisher wiley
30 results on '"Li, Xiao-Lin"'

3. Bicyclol Alleviates Atherosclerosis by Manipulating Gut Microbiota (Small 9/2022)

Author

Li, Xiao‐Lin, primary, Cui, Jin‐Jin, additional, Zheng, Wen‐Sheng, additional, Zhang, Jin‐Lan, additional, Li, Rui, additional, Ma, Xiao‐Lei, additional, Lin, Miao, additional, Guo, Hui‐Hui, additional, Li, Cong, additional, Yu, Xiao‐You, additional, Du, Peng, additional, Zhao, Li‐Min, additional, He, Shuwang, additional, Lan, Pei, additional, Jiang, Jian‐Dong, additional, Che, Yongsheng, additional, and Wang, Lu‐Lu, additional

Published
2022
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4. Dual‐Stimuli‐Responsive Gut Microbiota‐Targeting Berberine‐CS/PT‐NPs Improved Metabolic Status in Obese Hamsters

Author

Guo, Hui‐Hui, primary, Ma, Chen, additional, Zheng, Wen‐Sheng, additional, Luo, Yang, additional, Li, Cong, additional, Li, Xiao‐Lin, additional, Ma, Xiao‐Lei, additional, Feng, Chen‐Lin, additional, Zhang, Ting‐Ting, additional, Han, Yan‐Xing, additional, Luo, Zhi‐Gang, additional, Zhan, Yun, additional, Li, Rui, additional, Wang, Lu‐Lu, additional, and Jiang, Jian‐Dong, additional

Published
2020
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7. Dual‐Stimuli‐Responsive Gut Microbiota‐Targeting Berberine‐CS/PT‐NPs Improved Metabolic Status in Obese Hamsters

Author

Guo, Hui‐Hui, primary, Ma, Chen, additional, Zheng, Wen‐Sheng, additional, Luo, Yang, additional, Li, Cong, additional, Li, Xiao‐Lin, additional, Ma, Xiao‐Lei, additional, Feng, Chen‐Lin, additional, Zhang, Ting‐Ting, additional, Han, Yan‐Xing, additional, Luo, Zhi‐Gang, additional, Zhan, Yun, additional, Li, Rui, additional, Wang, Lu‐Lu, additional, and Jiang, Jian‐Dong, additional

Published
2019
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29. Improvement of oxidative stress status by lipoprotein apheresis in Chinese patients with familial hypercholesterolemia.

Author

Wen J, Dong Q, Liu G, Gao Y, Li XL, Jin JL, Li JJ, and Guo YL

Subjects
Adolescent, Adult, Aged, Asian People, Child, Female, Humans, Hyperlipoproteinemia Type II blood, Lipids blood, Male, Middle Aged, Treatment Outcome, Young Adult, Blood Component Removal methods, Hyperlipoproteinemia Type II therapy, Oxidative Stress
Abstract

Background and Aims: Familial hypercholesterolemia (FH) characterized by severe high blood cholesterol levels usually presents an imbalance of systemic oxidative stress (OS). Lipoprotein apheresis (LA), which is the most effective therapy to reduce cholesterol levels, remains unclear in altering OS and scarce in Chinese patient studies. Our study aims to assess the impact of LA on OS status in Chinese patients with FH., Methods: About 31 patients (22 males, age: 12-69 years) with FH and receiving LA treatment were consecutive enrolled. Free oxygen radicals test (FORT) and free oxygen radicals defense (FORD) values were determined using the free oxygen radical monitor and kit immediately before and after LA, while blood samples were collected to measure plasma lipid levels and hs-CRP by conventional methods. Data were analyzed by paired t test or rank sum test and Spearman-rho correlation analysis., Results: Besides plasma lipid levels, the OS status showed that FORTs were significantly decreased and FORD values significantly enhanced immediately after LA treatment compared with before (both P < .01). In addition, the correlation analysis showed that the removal rates (△%) of TC were positively related to the increased rates (△%) of FORD value (ρ = 0.513, P = .003); LDL-C to FORD (ρ = 0.39, P = .03); Lp(a) to FORD (ρ = 0.473, P = .007); and non-HDL-C to FORD (ρ = 0.46, P = .009). However, no significant difference in hsCRP was found., Conclusions: The present study indicated, besides effectively lowering plasma lipid levels, LA could significantly improve OS status in Chinese patients with FH., (© 2019 The Authors. Journal of Clinical Laboratory Analysis Published by Wiley Periodicals, Inc.)

Published
2020
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30. Novel findings in relation to multiple anti-atherosclerotic effects of XueZhiKang in humans.

Author

Xu RX, Zhang Y, Guo YL, Ma CY, Yao YH, Li S, Li XL, Qing P, Gao Y, Wu NQ, Zhu CG, Liu G, Dong Q, Sun J, and Li JJ

Abstract

Background: Previous studies have clearly demonstrated that XueZhiKang (XZK), an extract of cholestin, can decrease low-density lipoprotein cholesterol (LDL-C) and cardiovascular events. However, the mechanism of the effects of XZK on atherosclerosis (AS) in humans has been reported less frequently. In the present study, we investigated the impact of XZK on lipoprotein subfractions, oxidized LDL (oxLDL), and interleukin-6 (IL-6)., Methods: From October 2015 to July 2016, 40 subjects were enrolled in this study. Of them, 20 subjects with dyslipidemia received XZK 1200 mg/day for 8 weeks (XZK group); 20 additional healthy subjects who did not receive therapy acted as controls. The plasma lipoprotein subfractions, oxLDL, and IL-6 were examined at baseline and again at 8 weeks., Results: Data showed that XZK could significantly decrease not only plasma LDL-C levels (87.26 ± 24.45 vs . 123.34 ± 23.99, P  < 0.001), total cholesterol (4.14 ± 0.87 vs . 5.08 ± 1.03, P  < 0.001), triglycerides (0.95 ± 0.38 vs . 1.55 ± 0.61, P  < 0.05), and apolipoprotein B (1.70 ± 0.35 vs . 1.81 ± 0.72, P  < 0.05), but also oxLDL (36.36 ± 5.31 vs . 49.20 ± 15.01, P  < 0.05) and IL-6 (8.50 ± 7.40 vs . 10.40 ± 9.49, P  < 0.05). At the same time, XZK reduced the concentration of small LDL-C (1.78 ± 2.17 vs . 6.33 ± 7.78, P  < 0.05) and the percentage of the small LDL subfraction (1.09 ± 1.12 vs . 3.07 ± 3.09, P  < 0.05)., Conclusions: Treatment with 1200 mg/day XZK for 8 weeks significantly decreased the atherogenic small LDL subfraction and reduced oxidative stress and inflammatory markers, in addition to affecting the lipid profile, suggesting multiple beneficial effects in coronary artery disease.

Published
2017
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